메토트렉세이트 중단 이후 발생한무증상-류마티스수막염
Asymptomatic Rheumatoid Meningoencephalitis Presented After Discontinuation of Methotrexate
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Rheumatoid meningoencephalitis is a rare, but severe complication of rheumatoid arthritis (RA). A 64-year-old womanwith the history of RA presented with abnormal behaviors and memory impairments since stopping methotrexate due asymptomatic meningitis before 1 month. Brain MRI still demonstrated leptomeningeal enhancement in rightfronto-temporal area, compared with the previous. Brain biopsy revealed multiple yellowish suppurative streaks dura, and microscopically lymphoplasmic infiltrations and fibroid necrosis surrounded by granuloma. Soon afterbeginning treatment with corticosteroid and methotrexate, her symptoms improved.
Abstract
Rheumatoid meningoencephalitis is a rare, but severe complication of rheumatoid arthritis (RA). A 64-year-old womanwith the history of RA presented with abnormal behaviors and memory impairments since stopping methotrexate due asymptomatic meningitis before 1 month. Brain MRI still demonstrated leptomeningeal enhancement in rightfronto-temporal area, compared with the previous. Brain biopsy revealed multiple yellowish suppurative streaks dura, and microscopically lymphoplasmic infiltrations and fibroid necrosis surrounded by granuloma. Soon afterbeginning treatment with corticosteroid and methotrexate, her symptoms improved.
참고문헌 (9)
- Bathon JM, "Inflammatory central nervous system involvement in rheumatoid arthritis", Semin Arthritis Rheum, 18, pp.258~266 (1989)
- 이기정, "류마티스수막염: 신경계 증상과 병리 소견", 대한신경과학회지, 30(4), pp.301~304 (2012), 대한신경과학회
- Koide R, "Rheumatoid leptomeningitis: Rare complication of rheumatoid arthritis", Clin Rheumatol, 28, pp.1117~1119 (2009)
- Servioli MJ, "Rheumatoid meningitis", Front Neurol, 2, pp.84~ (2011)
- Huys AC, "Rheumatoid meningitis occurring during adalimumab and methotrexate treatment", Joint Bone Spine, 79, pp.90~92 (2012)
- Cianfoni A, "Rheumatoid leptomeningitis: Magnetic resonance imaging and pathologic findings--a case report", J Neuroimaging, 20, pp.192~194 (2010)
- Kato T, "Rheumatoid meningitis: An autopsy report and review of the literature", Clin Rheumatol, 22, pp.475~480 (2003)
- Chou RC, "Successful treatment of rheumatoid meningitis with cyclophosphamide but not infliximab", Ann Rheum Dis, 65, pp.1114~1116 (2006)
- Krysl D, "Chronic repetitive nonprogressive epilepsia partialis continua due to rheumatoid meningitis", Seizure, 22, pp.80~82 (2013)