전신홍반루푸스에서 면역억제제 치료 없이 발생한 크립토코쿠스 수막염
Cryptococcal Meningoencephalitis in a Systemic Lupus Erythematosus Patient without Immunosuppressants
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초록
저자들은 면역억제 치료를 받지 않고 있던 SLE 환자에서발생한 크립토코쿠스 수막뇌염을 보고한다. 본 증례를 통해면역억제 치료를 받지 않는 SLE 환자에서 비전형적 증상을동반한 두통을 호소할시 크립토코쿠스 수막염의 감별이 중요함을 보고하고자 한다.
Abstract
Cryptococcosis is an opportunistic infection that generally occurs in patients with cell-mediated immune dysfunction and involves the central nervous system. Infection is a major cause of morbidity and mortality in systemic lupus erythematosus (SLE) patients because of its innate immune dysfunction along with the administration of steroids and immunosuppressants. However, central nervous system cryptococcosis has rarely been reported in SLE patients. A timely diagnosis is critical because of its significant mortality and morbidity. Most cases of cryptococcal meningitis in SLE patients have been reported in those treated with steroids or immunosuppressants. We report on a SLE patient not on medication, who was diagnosed with cryptococcal meningoencephalitis.
참고문헌 (10)
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