류마티스수막염: 신경계 증상과 병리 소견
Rheumatoid Meningitis: Neurologic Manifestation and Pathologic Findings
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Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man with the history of rheumatoid arthritis presented with intermittent left leg weakness, seizures and later developed fever and confusion. Brain MRI demonstrated leptomeningeal enhancement in right fronto-parietal area. Brain biopsy revealed multifocal suppurative inflammation. After aggressive immunosuppressive treatment, he had gradually recovered and the lesion was reduced on a follow-up MRI.
Abstract
Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man with the history of rheumatoid arthritis presented with intermittent left leg weakness, seizures and later developed fever and confusion. Brain MRI demonstrated leptomeningeal enhancement in right fronto-parietal area. Brain biopsy revealed multifocal suppurative inflammation. After aggressive immunosuppressive treatment, he had gradually recovered and the lesion was reduced on a follow-up MRI.
참고문헌 (9)
- Shimada K, "Diffuse chronic leptomeningitis with seropositive rheumatoid arthritis: report of a case successfully treated as rheumatoid leptomeningitis", Mod Rheumatol, 19, pp.556~562 (2009)
- Kurne A, "An unusual central nervous system involvement in rheumatoid arthritis: combination of pachymeningitis and cerebral vasculitis", Rheumatol Int, 29, pp.1349~1353 (2009)
- Matsushima M, "MRI and pathological findings of rheumatoid meningitis", J Clin Neurosci, 17, pp.129~132 (2010)
- Kim HY, "A case of rheumatoid meningitis: pathologic and magnetic resonance imaging findings", Neurol Sci, 32, pp.1191~1194 (2011)
- Ellman P, "Widespread serous membrane involvement by rheumatoid nodules", J Clin Pathol, 7, pp.239~244 (1954)
- Cellerini M, "MRI of cerebral rheumatoid pachymeningitis: report of two cases with follow-up", Neuroradiology, 43, pp.147~150 (2001)
- Kato T, "Rheumatoid meningitis: an autopsy report and review of the literature", Clin Rheumatol, 22, pp.475~480 (2003)
- Markenson JA, "Rheumatoid meningitis: a localized immune process", Ann Intern Med, 90, pp.786~789 (1979)
- Chou RC, "Successful treatment of rheumatoid meningitis with cyclophosphamide but not infliximab", Ann Rheum Dis, 65, pp.1114~1116 (2006)
