본문 바로가기
KERD
논문KCI 등재

류마티스수막염: 신경계 증상과 병리 소견

Rheumatoid Meningitis: Neurologic Manifestation and Pathologic Findings

0

조회

0

다운로드

1

인용

0

참고문헌

키워드

주제분류신경과학

초록

Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man with the history of rheumatoid arthritis presented with intermittent left leg weakness, seizures and later developed fever and confusion. Brain MRI demonstrated leptomeningeal enhancement in right fronto-parietal area. Brain biopsy revealed multifocal suppurative inflammation. After aggressive immunosuppressive treatment, he had gradually recovered and the lesion was reduced on a follow-up MRI.

Abstract

Rheumatoid meningitis, one of the most severe complications of rheumatoid arthritis, presents various symptoms such as headache, confusion, loss of consciousness, seizure, fever, and focal neurological deficits. A 63-year-old man with the history of rheumatoid arthritis presented with intermittent left leg weakness, seizures and later developed fever and confusion. Brain MRI demonstrated leptomeningeal enhancement in right fronto-parietal area. Brain biopsy revealed multifocal suppurative inflammation. After aggressive immunosuppressive treatment, he had gradually recovered and the lesion was reduced on a follow-up MRI.

참고문헌 (9)

  1. Shimada K, "Diffuse chronic leptomeningitis with seropositive rheumatoid arthritis: report of a case successfully treated as rheumatoid leptomeningitis", Mod Rheumatol, 19, pp.556~562 (2009)
  2. Kurne A, "An unusual central nervous system involvement in rheumatoid arthritis: combination of pachymeningitis and cerebral vasculitis", Rheumatol Int, 29, pp.1349~1353 (2009)
  3. Matsushima M, "MRI and pathological findings of rheumatoid meningitis", J Clin Neurosci, 17, pp.129~132 (2010)
  4. Kim HY, "A case of rheumatoid meningitis: pathologic and magnetic resonance imaging findings", Neurol Sci, 32, pp.1191~1194 (2011)
  5. Ellman P, "Widespread serous membrane involvement by rheumatoid nodules", J Clin Pathol, 7, pp.239~244 (1954)
  6. Cellerini M, "MRI of cerebral rheumatoid pachymeningitis: report of two cases with follow-up", Neuroradiology, 43, pp.147~150 (2001)
  7. Kato T, "Rheumatoid meningitis: an autopsy report and review of the literature", Clin Rheumatol, 22, pp.475~480 (2003)
  8. Markenson JA, "Rheumatoid meningitis: a localized immune process", Ann Intern Med, 90, pp.786~789 (1979)
  9. Chou RC, "Successful treatment of rheumatoid meningitis with cyclophosphamide but not infliximab", Ann Rheum Dis, 65, pp.1114~1116 (2006)

관련 논문AI추천

이 간행물의 다른 논문 (32건)