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림프종에 의한 신생물딸림증후군으로 발현한 MOG항체양성척수병

MOG Antibody-Positive Myelopathy as a Paraneoplastic Manifestation of Lymphoma

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초록

Although myelin oligodendrocyte glycoprotein antibodyassociated disease (MOGAD) is an autoimmune demyelinating disease, it may occur as a paraneoplastic syndrome in rare instances. A 80yearold woman presented with paresthesia and weakness of four extremities for 10 days. Spine magnetic resonance imaging showed longitudinally extensive transverse myelitis. Laboratory tests revealed positive MOG antibodies. Both highdose intravenous methylprednisolone and plasma exchange were not effective and further evaluation showed lymphoma. Herein, we reported a case of MOGpositive paraneoplastic myelopathy with lymphoma.

Abstract

Although myelin oligodendrocyte glycoprotein antibodyassociated disease (MOGAD) is an autoimmune demyelinating disease, it may occur as a paraneoplastic syndrome in rare instances. A 80yearold woman presented with paresthesia and weakness of four extremities for 10 days. Spine magnetic resonance imaging showed longitudinally extensive transverse myelitis. Laboratory tests revealed positive MOG antibodies. Both highdose intravenous methylprednisolone and plasma exchange were not effective and further evaluation showed lymphoma. Herein, we reported a case of MOGpositive paraneoplastic myelopathy with lymphoma.

참고문헌 (10)

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