The Validity and Reliability of a Screening Questionnaire for Parkinson’s Disease in a Community
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Objectives: Parkinson’s disease is one of the most common neurodegenerative diseases in the elderly population. In order to estimate the prevalence of Parkinson’s disease in the community, the application of a good screening tool is essential. We evaluated the validity and reliability of a Parkinson’s disease screening questionnaire and propose an alternative measure to improve its validity for use in community surveys. Methods: We designed the study in a three-phase approach consisting of a screening questionnaire, neurologic examination, and confirmatory examination. A repeated survey was administered to patients with disease detected in the community and on 150 subjects. We examined internal consistency using Cronbach’s alpha test, test-retest reliability using the kappa statistic, and validity using sensitivity, specificity, and ROC curves. Unadjusted odds ratios were utilized for the estimation of weights for each questionnaire item. Results: The Cronbach’s alpha of the questionnaire was 0.708. The kappa statistic for test-retest reliability was good to generally fair in most of the items. When newly proposed weighting scores were used, the optimum cut-off value was 7/8. When cut-off value was 5/6 for surveying prevalence in a community, the sensitivity was 0.98, and the specificity was 0.61, with simultaneous improvement in reliability. Conclusions: We recommend 5/6 as the ideal cut-off value for the survey of PD prevalence in community. This questionnaire designed for the Korean community could help future epidemiologic studies of PD.
Abstract
Objectives: Parkinson’s disease is one of the most common neurodegenerative diseases in the elderly population. In order to estimate the prevalence of Parkinson’s disease in the community, the application of a good screening tool is essential. We evaluated the validity and reliability of a Parkinson’s disease screening questionnaire and propose an alternative measure to improve its validity for use in community surveys. Methods: We designed the study in a three-phase approach consisting of a screening questionnaire, neurologic examination, and confirmatory examination. A repeated survey was administered to patients with disease detected in the community and on 150 subjects. We examined internal consistency using Cronbach’s alpha test, test-retest reliability using the kappa statistic, and validity using sensitivity, specificity, and ROC curves. Unadjusted odds ratios were utilized for the estimation of weights for each questionnaire item. Results: The Cronbach’s alpha of the questionnaire was 0.708. The kappa statistic for test-retest reliability was good to generally fair in most of the items. When newly proposed weighting scores were used, the optimum cut-off value was 7/8. When cut-off value was 5/6 for surveying prevalence in a community, the sensitivity was 0.98, and the specificity was 0.61, with simultaneous improvement in reliability. Conclusions: We recommend 5/6 as the ideal cut-off value for the survey of PD prevalence in community. This questionnaire designed for the Korean community could help future epidemiologic studies of PD.
참고문헌 (24)
- Bower JH, "Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990", Neurology, 52(6), pp.1214~1220 (1999)
- Taylor CA, "Environmental, medical, and family history risk factors for Parkinson’s disease: A New England-based case control study", Am J Med Genet, 88(6), pp.742~749 (1999)
- Morgante L, "Prevalence of Parkinson’s disease and other types of parkinsonism: A door-to-door survey in three Sicilian municipalities", The Sicilian Neuro- Epidemiologic Study (SNES) Group. Neurology, 42(10), pp.1901~1907 (1992)
- Wang SJ, "Parkinson’s disease in Kin-Hu, Kinmen: A community survey by neurologists", Neuroepidemiology, 13(1), pp.69~74 (1994)
- MacDonald BK, "The incidence and lifetime prevalence of neurological disorders in a prospective community-based study in the UK", pp.665~676 (2000), Brain
- Newman EJ, "Geographical difference in Parkinson’s disease prevalence within West Scotland", Mov Disord, 3, pp.401~406 (2009)
- von Campenhausen S, "Prevalence and incidence of Parkinson’s disease in Europe", Eur Neuropsychopharmacol, 15(4), pp.473~490 (2005)
- Seo WK, "Prevalence of Parkinson’s disease in Korea", J Clin Neurosci, 14(12), pp.1155~1157 (2007)
- "Korea Centers for Disease Prevention and Control"[URL]
- Park J, "A retrospective cohort study of Parkinson’s disease in Korean shipbuilders", Neurotoxicology, 27(3), pp.445~449 (2006)
- Tanner CM, "Goetz CG. A brief screening questionnaire for parkinsonism", Ann Neurol, 28, pp.267~268 (1990)
- Duarte J, "Screening Parkinson’s disease: A validated questionnaire of high specificity and sensitivity", Mov Disord, 10(5), pp.643~649 (1995)
- Mutch WJ, "A screening and alerting questionnaire for parkinsonism", Neuroepidemiology, 10(3), pp.150~156 (1991)
- 주진형, "두 가지 한글판 간이정신상태평가(Mini-Mental State Examination)의 비교 : MMSE-KC와 K-MMSE", 신경정신의학, 44(1), pp.98~104 (2005), 대한신경정신의학회
- 양동원, "Korean Dementia Screeing Questionnaire (KDSQ)의 개발과 타당도 및 신뢰도의 평가", 대한신경과학회지, 20(2), pp.135~141 (2002), 대한신경과학회
- Taylor KS, "Screening for undiagnosed parkinsonism in people aged 65 years and over in the community", Parkinsonism Related Disord, 12(2), pp.79~85 (2006)
- Viera AJ, "Understanding interobserver agreement: The kappa statistic", Fam Med, 37(5), pp.360~363 (2005)
- Landis JR, "The measurement of observer agreement for categorical data", Biometrics, 33(1), pp.159~174 (1977)
- Yip CW, "Test-retest repeatability of assessing environmental and lifestyle factors in Parkinson’s disease", Mov Disord, 23(7), pp.1032~1036 (2008)
- Sarangmath N, "Validity of a modified Parkinson’s disease screening questionnaire in India: Effects of literacy of participants and medical training of screeners and implications for screening efforts in developing countries", Mov Disord, 20(12), pp.1550~1556 (2005)
- Chan DK, "Validating a screening questionnaire for parkinsonism in Australia", J Neurol Neurosurg Psychiatry, 69(1), pp.117~120 (2000)
- Racette BA, "A rapid method for mass screening for parkinsonism", Neurotoxicology, 27(3), pp.357~361 (2006)
- Nicoletti A, "A screening instrument for a Sicilian neuroepidemiological survey in the elderly", Arch Gerontol Geriatr, 38(1), pp.37~44 (2004)
- Racette BA, "Evaluation of a screening questionnaire for genetic studies of Parkinson’s disease", Am J Med Genet, 88(5), pp.539~543 (1999)