Validation of the Korean-Version of the Nonmotor Symptoms Scale for Parkinson’s Disease
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Background and Purpose Non-motor symptoms are common in Parkinson’s disease (PD),and are the primary cause of disability in many PD patients. Our aim in this study was to translate the origin non-motor symptoms scale for PD (NMSS), which was written in English, into Korean (K-NMSS), and to evaluate its reliability and validity for use with Korean-speaking patients with PD. Methods In total, 102 patients with PD from 9 movement disorders sections of university teaching hospitals in Korea were enrolled in this study. They were assessed using the K-NMSS,the Unified Parkinson’s Disease Rating Scale (UPDRS), the Korean version of the Mini-Mental Status Examination (K-MMSE), the Korean version of the Montgomery-Asberg Depression Rating Scale (K-MADS), the Epworth Sleepiness Scale (ESS), and Parkinson’s Disease Questionnaire 39 (PDQ39). Test-retest reliability was assessed over a time interval of 10-14 days in all but one patient. Results The K-NMSS was administered to 102 patients with PD. The internal consistency and reliability of this tool was 0.742 (mean Cronbach’s α-coefficient). The test-retest correlation reliability was 0.941 (Guttman split-half coefficient). There was a moderate correlation between the total K-NMSS score and the scores for UPDRS part I [Spearman’s rank correlation coefficient,(rS)=0.521, p<0.001] and UPDRS part II (rS=0.464, p=0.001), but there was only a weak correlation between the total K-NMSS score and the UPDRS part III score (rS=0.288, p=0.003). The total K-NMSS score was significantly correlated with the K-MADS (rS=0.594, p<0.001), KMMSE (rS=-0.291, p=0.003), and ESS (rS=0.348, p<0.001). The total K-NMSS score was also significantly and positively correlated with the PDQ39 score (rS=0.814, p<0.001). Conclusions The K-NMSS exhibited good reliability and validity for the assessment of nonmotor symptoms in Korean PD patients.
Abstract
Background and Purpose Non-motor symptoms are common in Parkinson’s disease (PD),and are the primary cause of disability in many PD patients. Our aim in this study was to translate the origin non-motor symptoms scale for PD (NMSS), which was written in English, into Korean (K-NMSS), and to evaluate its reliability and validity for use with Korean-speaking patients with PD. Methods In total, 102 patients with PD from 9 movement disorders sections of university teaching hospitals in Korea were enrolled in this study. They were assessed using the K-NMSS,the Unified Parkinson’s Disease Rating Scale (UPDRS), the Korean version of the Mini-Mental Status Examination (K-MMSE), the Korean version of the Montgomery-Asberg Depression Rating Scale (K-MADS), the Epworth Sleepiness Scale (ESS), and Parkinson’s Disease Questionnaire 39 (PDQ39). Test-retest reliability was assessed over a time interval of 10-14 days in all but one patient. Results The K-NMSS was administered to 102 patients with PD. The internal consistency and reliability of this tool was 0.742 (mean Cronbach’s α-coefficient). The test-retest correlation reliability was 0.941 (Guttman split-half coefficient). There was a moderate correlation between the total K-NMSS score and the scores for UPDRS part I [Spearman’s rank correlation coefficient,(rS)=0.521, p<0.001] and UPDRS part II (rS=0.464, p=0.001), but there was only a weak correlation between the total K-NMSS score and the UPDRS part III score (rS=0.288, p=0.003). The total K-NMSS score was significantly correlated with the K-MADS (rS=0.594, p<0.001), KMMSE (rS=-0.291, p=0.003), and ESS (rS=0.348, p<0.001). The total K-NMSS score was also significantly and positively correlated with the PDQ39 score (rS=0.814, p<0.001). Conclusions The K-NMSS exhibited good reliability and validity for the assessment of nonmotor symptoms in Korean PD patients.
참고문헌 (16)
- Chaudhuri KR, "The challenge of non-motor symptoms in Parkinson’s disease", Prog Brain Res, 184, pp.325~341 (2010)
- Martinez-Martin P, "The impact of non-motor symptoms on health-related quality of life of patients with Parkinson’s disease", Mov Disord, 26, pp.399~406 (2011)
- Chaudhuri KR, "The metric properties of a novel non-motor symptoms scale for Parkinson’s disease: Results from an international pilot study", Mov Disord, 22, pp.1901~1911 (2007)
- Hughes AJ, "The clinical features of Parkinson’s disease in 100 histologically proven cases", Adv Neurol, 60, pp.595~599 (1993)
- Langston JW, "Core assessment program for intracerebral transplantations (CAPIT)", Mov Disord, 7, pp.2~13 (1992)
- Hoehn MM, "Parkinsonism: onset, progression and mortality", Neurology, 17, pp.427~442 (1967)
- Movement Disorder Society Task Force on Rating Scales for Parkinson’s Disease, "The Unified Parkinson’s Disease Rating Scale (UPDRS): status and recommendations", Mov Disord, 18, pp.738~750 (2003)
- Kang Y, "A validity study on the Korean Mini-Mental State Examination (K-MMSE) in dementia patients", J Korean Neurol Assoc, 15, pp.300~308 (1997)
- 안용민, "한글판 Montgomery-Åsberg 우울증 평가 척도의 표준화 연구", 신경정신의학, 44(4), pp.466~476 (2005), 대한신경정신의학회
- Johns MW, "A new method for measuring daytime sleepiness: the Epworth sleepiness scale", Sleep, 14, pp.540~545 (1991)
- Peto V, "The development and validation of a short measure of functioning and well being for individuals with Parkinson’s disease", Qual Life Res, 4, pp.241~248 (1995)
- Wang G, "Validation of the Chinese non-motor symptoms scale for Parkinson’s disease: results from a Chinese pilot study", Clin Neurol Neurosurg, 11, pp.523~526 (2009)
- Santos JR, "Cronbach’s alpha: a tool for assessing the reliability of scales", J Ext, 37, pp.T2~T3 (1999)
- "Assessing health status and quality-of-life instruments: attributes and review criteria", Qual Life Res, 11, pp.193~205 (2002)
- Bayulkem K, "Nonmotor fluctuations in Parkinson’s disease: clinical spectrum and classification", J Neurol Sci, 289, pp.89~92 (2010)
- Poewe W, "Levodopa in the treatment of Parkinson’s disease: an old drug still going strong", Clin Interv Aging, 5, pp.229~238 (2010)