국내산 개똥쑥 소수성 분획물의 항산화 활성 및 항주름 효과 탐색
Exploration of Antioxidant Activity and Anti-wrinkle Effect of Hydrophobic Fractions of Domestic Artemisia annua L.
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초록
Artemisia annua belongs to the plant family of Asteraceae and is an annual short-day plant. This plant is known for its various effects such as its anti-cancer, anti-antioxidant, anti-inflammatory, and cardiovascular disease therapies. However, the anti-wrinkle effect of the hydrophobic fraction extract has not been reported yet. In this study, the antioxidant activity and anti-wrinkle activity of the number of hydrophobic fractions of domestic Artemisia annua L is investigated. Three solvent extracts (hot water, 70% ethanol, and 100% methanol) of Artemisia annua L are prepared. In the evaluation results of Artemisia annua L. leaf, antioxidant and anti-wrinkle activities are uncovered. The 100% methanol extract shows the highest antioxidant activities and total phenolic and total flavonoid contents among them. Collagenase inhibition, ellstase inhibition, and hyaluronidase inhibition IC50 rate are 124, 200, and 324 ug/mL, respectively. Therefore, this plant would be a useful anti-wrinkle cosmetic material.
Abstract
Artemisia annua belongs to the plant family of Asteraceae and is an annual short-day plant. This plant is known for its various effects such as its anti-cancer, anti-antioxidant, anti-inflammatory, and cardiovascular disease therapies. However, the anti-wrinkle effect of the hydrophobic fraction extract has not been reported yet. In this study, the antioxidant activity and anti-wrinkle activity of the number of hydrophobic fractions of domestic Artemisia annua L is investigated. Three solvent extracts (hot water, 70% ethanol, and 100% methanol) of Artemisia annua L are prepared. In the evaluation results of Artemisia annua L. leaf, antioxidant and anti-wrinkle activities are uncovered. The 100% methanol extract shows the highest antioxidant activities and total phenolic and total flavonoid contents among them. Collagenase inhibition, ellstase inhibition, and hyaluronidase inhibition IC50 rate are 124, 200, and 324 ug/mL, respectively. Therefore, this plant would be a useful anti-wrinkle cosmetic material.
참고문헌 (16)
- Lodari, C., , Jpn. J. Breed, 39, pp.9~12 (1989)
- Li, L., , Front. Plant Sci, 8, pp.1~10 (2017)
- 류지현, "개똥쑥의 영양적 특성 및 생리활성", 한국식품영양과학회지, 40(2), pp.163~170 (2011), 한국식품영양과학회
- Tu, Y., , Nat. Med, 17, pp.17~ (2011)
- Charles, D. J., , Essent. Oil Res, 3, pp.33~39 (1991)
- 김경범, "국내 유통 중인 식용식물 추출물의 항산화효과", Applied Biological Chemistry, 49(4), pp.328~333 (2006), 한국응용생명화학회
- Park, E. J., , LWT-Food Sci. Technol, 43, pp.655~659 (2010)
- 이승욱, "울릉도산 산채류 추출물의 총 폴리페놀 함량 및 항산화 활성", 한국식품과학회지, 37(2), pp.233~240 (2005), 한국식품과학회
- 최소영, "멜라닌 세포에서 홍차 열수추출물의 멜라닌 합성 저해능과 작용기전", Applied Microscopy, 41(3), pp.169~177 (2011), 한국현미경학회
- Seok Hyun Eom, "Changes in Antioxidant Activity with Temperature and Time in Chrysanthemum indicum L. (Gamguk) Teas During Elution Processes in Hot Water", Food Science and Biotechnology, 17(2), pp.408~412 (2008), 한국식품과학회
- 곽윤진, "각종 약용 식물로부터 피부노화 억제 관련 elastase 저해물질의탐색 및 추출조건", 한국약용작물학회지, 13(6), pp.213~216 (2005), 한국약용작물학회
- Kornicka, K., , RSC Adv, 7, pp.24070~24084 (2017)
- 정인창, "쑥 분말이 첨가된 식빵의 물성 및 관능성", 동아시아식생활학회지, 16(3), pp.332~343 (2006), 동아시아식생활학회
- 최소라, "사철쑥의 항산화성과 항균성", 한국약용작물학회지, 16(2), pp.112~117 (2008), 한국약용작물학회
- Jeon, H., , Kor. J. Herbology, 18, pp.187~ (2003)
- Bo Young Sin, "Inhibition of Collagenase by Naturally-Occurring Flavonoids", Archives of Pharmacal Research, 28(10), pp.1152~1155 (2005), 대한약학회