지역사회 주민을 대상으로 한 천식과 골다공증과의 연관성
The Association of Asthma and Osteoporosis in the Residents of the Local Community
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본 연구는 천식과 골다공증유병유무와의 관련 성을 알아봄으로써 골다공증의 예방 및 관리의 기초 자료로 제공하기 위해 시도되었다. 연구의 기초 자료는 ‘2008년 지역사회건강조사’ 를 이용 하였다. 조사 시기는 2008년 9월부터 2008년 11 월 까지였고, 충남의 7개 군 및 대전시 서구에 거주하는 19세 이상 주민 6,348명을 대상으로 하 였다. 이 중 천식이 있다고 응답한 203명 및 골 다공증이 있다고 대답한 465명의 특성을 질병이 없는 군의 특성과 비교하였다. 천식 유병유무와 골다공증 유병유무와는 유의한 상관관계가 있었 고, 천식대상자 중에서 천식치료여부와 골다공증 유병유무와도 유의한 상관관계가 있었다. 추가로 좀 더 광범위한 연구 분석과 추적조사가 필요하 리라 사료된다.
Abstract
Objectives: Corticosteroids, usually as an inhaled form, are usually used to treat narrowed airway in the treatment of asthma. However, the use of corticosteroid commonly associated with the development of osteoporosis. In this study, we studied the association of asthma and osteoporosis in the residents of the local community. Methods: As a part of the Local Community Health Study Chungnam 2008, the residents are surveyed with the formal questionnaire. We analyzed the association between asthma and osteoporosis data with the questionnaire. Results: We analyzed total 6,348 data from the residents in Chungnam province. Of them, 203(3.2%) were asthma patients and 465(7.3%) were osteoporosis patients. Patients with asthma have more advanced age(p<0.001), higher incidence of hypertension(p<0.001) and diabetes(p=0.001), lower incidence of exercise (p=0.002) and economic activity(p<0.001). Patients with osteoporosis have more advanced age (p<0.001), female predominance(p<0.001), higher incidence of hypertension (p<0.001), diabetes(p=0.001), and fractures (p<0.001), lower incidence of exercise (p=0.002) and economic activity (p<0.001). In total population, asthma is associated with the increased incidence of osteoporosis, especially in patients treated with anti-asthmatic medications. Conclusions: Through this study, we demonstrated the presence of asthma is closely associated with the increased incidence of osteoporosis, especially in patients treated with anti-asthmatic medications. Therefore, further and broad study will be needed to evaluate the association of asthma and the types of anti-asthmatic medications in the development of osteoporosis.
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