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일부 농촌여성들의 골다공증 유병률과 그 관련요인

The Prevalence of Osteoporosis and Its Related Factors among Some Rural Women

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본 연구는 지역사회 주민들을 대상으로 정량적 초음파법으로 진단한 골다공증의 유병률을 파악하고 관련요인을 규명하여 농촌지역 주민들에 대한 골다공증의 예방 교육 자료로 개발과 동시에 향후 전향적인 골다공증 연구에 대한 기초 자료를 제공하기 위하여 수행되어졌다. 본 연구에서는 전라남도 나주시 봉황면에 거주하는 40~70세 남녀주민을 대상자로 하여 2006년 1월부터 45일간 질병관리본부·유전체 역학 연구사업 일환으로 시행된 건강검진에 응한 986명중 남성 390명을 제외한 596명의 여성을 최종연구대상으로 하였으며 골다공증 관련요인을 분석할 때는 골감소증(-2.5<골밀도(T-score)<-1.0)으로 판정된 여성 208명을 제외한 388명을 대상으로 하였다. 전체 조사대상자들의 골다공증 유병률은 19.0%였으며, 골다공증 유병여부를 종속변수로 한 다중로지스틱 회귀분석 결과 교육수준이 무학인 여성에 비해 초졸 여성의 비차비는 0.34 (95%신뢰구간 0.16~ 0.73)이었고 비만도가 25 kg/m2이하인 여성에 비해 비만도가 25 kg/m2 이상인 경우의 비차비는 0.32 (95%신뢰구간 0.15-0.70)이었으며 초경연령이 15세 이하인 여성보다 20세 이후로 초경을 늦게 경험한 여성의 비차비는 4.73 (95%신뢰구간 1.27~17.7)이었다. 결론적으로 골다공증은 연구대상자의 사회경제적 상태, 건강행태, 체격상태, 초경연령 등이 관련인자이었으며 예방조치를 위한 위험인자를 규명하기 위해서는 지속적인 연구가 필요하였다.

Abstract

Objectives: This study was conducted to find the prevalence of osteoporosis and its related factors among rural women as basic data to develope educational materials to prevent and for longitudinal observatory study. Methods: Toward 596 40~70 year old women living in Bongwhang Township, Naju City, Chollanamdo, examinations including quantitative ultrasound (QUS) bone densitometry, questionnaire survey for life-style, anthropologic measurements and blood tests were performed for 45 days from January 9th, 2006. Osteoporosis was defined as T score -2.5 or below and T score -1.0 or above was nominated as normal group. Odds ratios (OR) with 95% confidence interval of osteoporosis group versus normal group were calculated by potential risk factors. Multiple logistic regression analysis was performed to find significant and dependent related factors. Results: The prevalence of osteoporosis among the subjects was 19.0%. The multiple logistic regression analysis showed that the OR of osteoporosis among elementary educated group compared to non-educated group was 0.34 (95%CI: 0.16~0.73). The OR of osteoporosis among subjects whose body mass index (BMI) were 25 kg/m2 or more against lower than 25 kg/m2 was 0.32 (95%CI: 0.15~0.70). The OR of osteoporosis among subjects who had started menarche later than 20 years old as compared to subjects who had started menarche before 15 years old was 4.73 (95%CI: 1.27~17.7). Conclusions: Late menarche age was the risk factor toward osteoporosis, while high education and high BMI were the protective factors against osteoporosis in study population.

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