Effects of Virtual Reality-Based Cognitive Training in the Elderly with and without Mild Cognitive Impairment
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초록
Objective This study aimed to introduce a 4-week long fully immersive virtual reality-based cognitive training (VRCT) program that could be applied for both a cognitively normal elderly population and patients with mild cognitive impairment (MCI). In addition, we attempted to investigate the neuropsychological effects of the VRCT program in each group.Methods A total of 56 participants, 31 in the MCI group and 25 in the cognitively normal elderly group, underwent eight sessions of VRCT for 4 weeks. In order to evaluate the effects of the VRCT, the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet was administered before and after the program. The program’ s safety was assessed using a simulator sickness questionnaire (SSQ), and availability was assessed using the presence questionnaire.Results After the eighth session of the VRCT program, cognitive improvement was observed in the ability to learn new information, visuospatial constructional ability, and frontal lobe function in both groups. At the baseline evaluation, based on the SSQ, the MCI group complained of disorientation and nausea significantly more than the cognitively normal elderly group did. However, both groups showed a reduction in discomfort as the VRCT program progressed.Conclusion We conclude that our VRCT program helps improve cognition in both the MCI group and cognitively normal elderly group. Therefore, the VRCT is expected to help improve cognitive function in elderly populations with and without MCI.
Abstract
Objective This study aimed to introduce a 4-week long fully immersive virtual reality-based cognitive training (VRCT) program that could be applied for both a cognitively normal elderly population and patients with mild cognitive impairment (MCI). In addition, we attempted to investigate the neuropsychological effects of the VRCT program in each group.Methods A total of 56 participants, 31 in the MCI group and 25 in the cognitively normal elderly group, underwent eight sessions of VRCT for 4 weeks. In order to evaluate the effects of the VRCT, the Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet was administered before and after the program. The program’ s safety was assessed using a simulator sickness questionnaire (SSQ), and availability was assessed using the presence questionnaire.Results After the eighth session of the VRCT program, cognitive improvement was observed in the ability to learn new information, visuospatial constructional ability, and frontal lobe function in both groups. At the baseline evaluation, based on the SSQ, the MCI group complained of disorientation and nausea significantly more than the cognitively normal elderly group did. However, both groups showed a reduction in discomfort as the VRCT program progressed.Conclusion We conclude that our VRCT program helps improve cognition in both the MCI group and cognitively normal elderly group. Therefore, the VRCT is expected to help improve cognitive function in elderly populations with and without MCI.
참고문헌 (32)
- Prince M, "The global prevalence of dementia : a systematic review and metaanalysis", Alzheimers Dement, 9, pp.63~75 (2013)
- Wimo A, "The worldwide economic impact of dementia 2010", Alzheimers Dement, 9, pp.1~11 (2013)
- Knopman DS, "Spectrum of cognition short of dementia : Framingham Heart Study and Mayo Clinic Study of Aging", Neurology, 85, pp.1712~1721 (2015)
- Petersen RC, "Mild cognitive impairment : transition between aging and Alzheimer’s disease", Neurologia, 15, pp.93~101 (2000)
- Muayqil T, "Systematic review and meta-analysis of combination therapy with cholinesterase inhibitors and memantine in Alzheimer’s disease and other dementias", Dement Geriatr Cogn Dis Extra, 2, pp.546~572 (2012)
- Yamaguchi H, "Overview of non-pharmacological intervention for dementia and principles of brain-activating rehabilitation", Psychogeriatrics, 10, pp.206~213 (2010)
- Hill NT, "Computerized cognitive training in older adults with mild cognitive impairment or dementia : a systematic review and meta-analysis", Am J Psychiatry, 174, pp.329~340 (2017)
- Mayeux R, "Treatment of Alzheimer’s disease", New Engl J Med, 341, pp.1670~1679 (1999)
- García-Betances RI, "Computerized neurocognitive interventions in the context of the brain training controversy", Rev Neurosci, 29, pp.55~69 (2017)
- Zygouris S, "A preliminary study on the feasibility of using a virtual reality cognitive training application for remote detection of mild cognitive impairment", J Alzheimers Dis, 56, pp.619~627 (2017)
- Ge S, "Technology-based cognitive training and rehabilitation interventions for individuals with mild cognitive impairment : a systematic review", BMC Geriatr, 18, pp.213~ (2018)
- Kim O, "The effectiveness of virtual reality for people with mild cognitive impairment or dementia : a meta-analysis", BMC Psychiatry, 19, pp.219~ (2019)
- Basak C, "Technology and Health", pp.215~235 (2018), Elsevier
- Petersen RC, "Mild cognitive impairment as a diagnostic entity", J Intern Med, 256, pp.183~194 (2004)
- 박정운, "경도인지장애 개선을 위한 VR 콘텐츠 개발 연구", 차세대컨버전스정보서비스기술논문지, 7(2), pp.149~162 (2018), 차세대컨버전스정보서비스학회[DOI]
- Kjeldskov J, "Interaction: Full and Partial Immersive Virtual Reality Displays", IRIS 24: Proceedings of the 24th Information Systems Research Seminar in Scandinavia, pp.587~600 (2001)
- Lee JH, "Development of the Korean Version of the Consortium to Establish a Registry for Alzheimer’s Disease Assessment Packet(CERAD-K)clinical and neuropsychological assessment batteries", J Gerontol B Psychol Sci Soc Sci, 57, pp.47~53 (2002)
- 김희진, "알츠하이머병 환자에서의 삶의 질 평가", 대한신경과학회지, 26(4), pp.308~313 (2008), 대한신경과학회
- Jung IK, "A study of standardization of Korean form of Geriatric Depression Scale(KGDS)", J Korean Geriatr Psychiatr, 1, pp.61~72 (1997)
- Kennedy RS, "Simulator sickness questionnaire : an enhanced method for quantifying simulator sickness", Int J Aviat Psychol, 3, pp.203~220 (1993)
- 오기성, "설문을 활용한 VR 콘텐츠의 사용자 경험 평가 연구", 디지털예술공학멀티미디어논문지, 5(2), pp.135~146 (2018), 차세대컨버전스정보서비스학회[DOI]
- Witmer BG, "Measuring presence in virtual environments : A presence questionnaire", Presence, 7, pp.225~240 (1998)
- Lombard M, "Measuring presence: the temple presence inventory", Proceedings of the 12th annual international workshop on presence, pp.1~15 (2009)
- Man DW, "Evaluation of a virtual reality-based memory training programme for Hong Kong Chinese older adults with questionable dementia : a pilot study", Int J Geriatr Psychiatry, 27, pp.513~520 (2012)
- Zając-Lamparska L, "Effects of virtual realitybased cognitive training in older adults living without and with mild dementia : a pretest–posttest design pilot study", BMC Res Notes, 12, pp.776~ (2019)
- Saredakis D, "Factors associated with virtual reality sickness in head-mounted displays : a systematic review and meta-analysis", Front Hum Neurosci, 14, pp.96~ (2020)
- Kennedy RS, "Virtual and Adaptive Environments: Applications, Implications, and Human Performance Issues", pp.247~278 (2003), CRC press
- Park GD, "Simulator sickness scores according to symptom susceptibility, age, and gender for an older driver assessment study", Proceedings of the human factors and ergonomics society annual meeting, 50, pp.2702~2706 (2006)
- Liu L, "VR for the elderly : quantitative and qualitative differences in performance with a driving simulator", Cyberpsychol Behav, 2, pp.567~576 (1999)
- Riva G, "Being There: Concepts, Effects and Measurements of User Presence in Synthetic Environments" (2003), IOS Press
- Grealy MA, "Improving cognitive function after brain injury : the use of exercise and virtual reality", Arch Phys Med Rehabil, 80, pp.661~667 (1999)
- Li H, "Cognitive intervention for persons with mild cognitive impairment : a meta-analysis", Ageing Res Rev, 10, pp.285~296 (2011)