컴퓨터 인지훈련프로그램 사용 후 인지기능의 효과성 분석
The Effect of Computer-Based Cognitive Training Program On Cognition
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초록
Background: Effective non-pharmacological cognitive program to prevent Alzheimer’s dementia or slow its progression are an urgent international priority. The effect of computer-based cognitive training program has not been demonstrated yet in dementia. The purpose of this study is to know whether the computer- based cognitive training improved cognitive abilities in patients with mild cognitive disorder and early stage of dementia. Methods: Totally 20 participants (14 with MCI and 6 with mild Alzhiemer dementia) participated in this study. To test the effectiveness of computer-based cognitive training programs to cognition, all patient were randomly allocated to an intervention group (n= 10) or a control group (n= 10) An intervention group received regularly computer-based cognitive training totally 20 times for 10 weeks. Neuropsychological examinations were conducted before and after this period. Results: After 10 weeks, intervention group showed a significant change in language of K-MMSE compared with baseline cognitive examinations. Also, there was improvement in attention (backward digit span), calculation, memory, and frontal function for the intervention group as compared with controls. Patients with mild cognitive disorder showed marked improvements in language and visuospatial capacity, while patients with dementia showed no or slight improvement in these fields. Conclusions: Computer-based cognitive training program might have beneficial effect on general cognitive function in both mild cognitive disorder and dementia. Especially, conspicuous effectiveness showed in patients with mild cognitive disorder.
Abstract
Background: Effective non-pharmacological cognitive program to prevent Alzheimer’s dementia or slow its progression are an urgent international priority. The effect of computer-based cognitive training program has not been demonstrated yet in dementia. The purpose of this study is to know whether the computer-based cognitive training improved cognitive abilities in patients with mild cognitive disorder and early stage of dementia. Methods: Totally 20 participants (14 with MCI and 6 with mild Alzhiemer dementia) participated in this study. To test the effectiveness of computer-based cognitive training programs to cognition, all patient were randomly allocated to an intervention group (n=10) or a control group (n=10) An intervention group received regularly computer-based cognitive training totally 20 times for 10 weeks. Neuropsychological examinations were conducted before and after this period. Results: After 10 weeks, intervention group showed a significant change in language of K-MMSE compared with baseline cognitive examinations. Also, there was improvement in attention (backward digit span), calculation, memory, and frontal function for the intervention group as compared with controls. Patients with mild cognitive disorder showed marked improvements in language and visuospatial capacity, while patients with dementia showed no or slight improvement in these fields. Conclusions: Computer-based cognitive training program might have beneficial effect on general cognitive function in both mild cognitive disorder and dementia. Especially, conspicuous effectiveness showed in patients with mild cognitive disorder.
참고문헌 (24)
- Wimo A, "The worldwide economic impact of dementia 2010", Alzheimers Dement, 9, pp.1~e13 (2013)
- Muayqil T, "Systematic review and meta-analysis of combination therapy with cholinesterase inhibitors and memantine in Alzheimer’s disease and other dementias", Dement Geriatr Cogn Dis Extra, 2, pp.546~572 (2012)
- Royall DR, "The cognitive correlates of functional status: a review from the Committee on Research of the American Neuropsychiatric Association", J Neuropsychiatry Clin Neurosci, 19, pp.249~265 (2007)
- Yamaguchi H, "Overview of non-pharmacological intervention for dementia and principles of brain-activating rehabilitation", Psychogeriatrics, 10, pp.206~213 (2010)
- Clare L, "Awareness in earlystage Alzheimer’s disease: relationship to outcome of cognitive rehabilitation", J Clin Exp Neuropsychol, 26, pp.215~226 (2004)
- Woolf CJ, "Neuronal plasticity: increasing the gain in pain", Science, 288, pp.1765~1769 (2000)
- Yu F, "Cognitive training for early-stage Alzheimer’s disease and dementia", J Gerontol Nurs, 35, pp.23~29 (2009)
- Zhuang JP, "The impact of human-computer interaction-based comprehensive training on the cognitive functions of cognitive impairment elderly individuals in a nursing home", J Alzheimers Dis, 36, pp.245~251 (2013)
- Glisky EL, "Long-term retention of computer learning by patients with memory disorders", Neuropsychologia, 26, pp.173~178 (1988)
- Palmese CA, "The rehabilitation of attention in individuals with mild traumatic brain injury, using the APT-II programme", Brain Inj, 14, pp.535~548 (2000)
- Petersen RC, "Current concepts in mild cognitive disorder", Arch Neurol, 58, pp.1985~1992 (2001)
- McKhann G DD, "Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer’s disease", Neurology, 34, pp.6~ (1984)
- 강연욱, "K-MMSE(Korean-Mini Mental State Examination)의 노인 규준 연구", 한국심리학회지:일반, 25(2), pp.1~12 (2006), 한국심리학회
- JC M, "Clinical dementia rating: a reliable and valid diagnostic and staging measure for dementia of the Alzheimer type", Int Psychogeriatr, 9, pp.4~ (1997)
- Kang YW, "Seoul neuropsychological screening battery" (2003), Human Brain Research & Consulting Co.
- Kim H, "Normative data on the Korean version of the Boston Naming Test", J Clin Exp Neuropsychol, 21, pp.127~133 (1999)
- Meyers KR, "Rey Complex Figure Test and recognition trial: professional manual" (1995), Psychological Assessment Resources
- Kang YW, "A normative study of the Korean version of Controlled Oral Word Association Test (COWAT) in the elderly", Kor J Clin Psychol, 19, pp.8~ (2000)
- Lee JH, "Efficiencies of Stroop Interference Indexes in Healthy Older Adults and Dementia Patients", Kor J Clin Psychol, 19, pp.12~ (2000)
- Hofmann M, "Computer-based cognitive training in Alzheimer’s disease patients", Ann N Y Acad Sci, 777, pp.249~254 (1996)
- Lee GY, "Evaluation of a computer-assisted errorless learning-based memory training program for patients with early Alzheimer’s disease in Hong Kong: a pilot study", Clin Interv Aging, 8, pp.623~633 (2013)
- Li H, "Cognitive intervention for persons with mild cognitive disorder: a meta-analysis", Ageing Res Rev, 10, pp.285~296 (2011)
- Jansen DA, "Identifying the attentional demands perceived by elderly people", Rehabil Nurs, 23, pp.12~20 (1998)
- Aguirre E, "Cognitive stimulation for dementia: a systematic review of the evidence of effectiveness from randomised controlled trials", Ageing Res Rev, 12, pp.253~262 (2013)
