Effects of Home Based Serious Game Training (Brain Talk™) in the Elderly With Mild Cognitive Impairment: Randomized, a Single-Blind, Controlled Trial
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Mild cognitive impairment (MCI) increases with aging society. Serious games may be effective in improving cognitive function in patients with MCI; however, research on their effects remains insufficient. This study aimed to confirm the efficacy and safety of cognitive rehabilitation training using a serious game (Brain Talk™) for the elderly with MCI. Twenty- four elderly individuals with MCI were randomized into study and control groups. The study group received 12 training sessions (30 min/session, 3 times/week), whereas the control group did not receive training. Blinded evaluations were conducted before and after the training and four weeks after the training. The primar y outcome measures were the Korean Mini-Mental State Examination (K-MMSE) and K-MoCA (Korean Montreal Cognitive Assessment). Secondar y outcome measures were the Semantic Verbal Fluency Task (SVFT), Trail-Making Test-B, and 2-back test. In the study group, the K-MMSE, K-MoCA, and SVFT scores after finishing the training and 4 weeks after training showed a significant increase; however, there was no significant change in the control group. No significant differences were obser ved between the two groups. Cognitive function significantly improved in the study group after training. Home-based serious games are considered helpful in improving cognitive function
Abstract
Mild cognitive impairment (MCI) increases with aging society. Serious games may be effective in improving cognitive function in patients with MCI; however, research on their effects remains insufficient. This study aimed to confirm the efficacy and safety of cognitive rehabilitation training using a serious game (Brain Talk™) for the elderly with MCI. Twenty- four elderly individuals with MCI were randomized into study and control groups. The study group received 12 training sessions (30 min/session, 3 times/week), whereas the control group did not receive training. Blinded evaluations were conducted before and after the training and four weeks after the training. The primar y outcome measures were the Korean Mini-Mental State Examination (K-MMSE) and K-MoCA (Korean Montreal Cognitive Assessment). Secondar y outcome measures were the Semantic Verbal Fluency Task (SVFT), Trail-Making Test-B, and 2-back test. In the study group, the K-MMSE, K-MoCA, and SVFT scores after finishing the training and 4 weeks after training showed a significant increase; however, there was no significant change in the control group. No significant differences were obser ved between the two groups. Cognitive function significantly improved in the study group after training. Home-based serious games are considered helpful in improving cognitive function
참고문헌 (40)
- Salthouse TA, "Selective review of cognitive aging", J Int Neuropsychol Soc, 16, pp.754~760 (2010)
- United Nations, "World population prospects 2019: highlights", pp.125~ (2019), United Nations, Department for Economic Social Affairs
- Petersen RC, "Mild cognitive impairment : transition between aging and Alzheimer’s disease", Neurologia, 15, pp.93~101 (2000)
- Gauthier S, "International Psychogeriatric Association Expert Conference on mild cognitive impairment. Mild cognitive impairment", Lancet, 367, pp.1262~1270 (2006)
- Geslani DM, "Mild cognitive impairment : an operational definition and its conversion rate to Alzheimer’s disease", Dement Geriatr Cogn Disord, 19, pp.383~389 (2005)
- Schaller S, "The main cost drivers in dementia : a systematic review", Int J Geriatr Psychiatry, 30, pp.111~129 (2015)
- Livingston G, "Dementia prevention, intervention, and care", Lancet, 390, pp.2673~2734 (2017)
- Manera V, "Recommendations for the use of serious games in neurodegenerative disorders : 2016 Delphi Panel", Front Psychol, 8, pp.1243~ (2017)
- Manera V, "‘Kitchen and cooking, ’ a serious game for mild cognitive impairment and Alzheimer’s disease : a pilot study", Front Aging Neurosci, 7, pp.24~ (2015)
- Tong T, "A serious game for clinical assessment of cognitive status : validation study", JMIR Serious Games, 4, pp.e7~ (2016)
- Petersen RC, "Mild cognitive impairment : clinical characterization and outcome", Arch Neurol, 56, pp.303~308 (1999)
- Kang Y, "A validity study on the Korean Mini-Mental State Examination(K-MMSE)in dementia patients", J Korean Neurol Assoc, 15, pp.300~308 (1997)
- Lee JY, "Brief screening for mild cognitive impairment in elderly outpatient clinic : validation of the Korean version of the Montreal Cognitive Assessment", J Geriatr Psychiatry Neurol, 21, pp.104~110 (2008)
- 강연욱, "혈관성 인지장애 선별검사로서 Korean-Montreal Cognitive Assessment(K-MoCA)의 신뢰도, 타당도 및 규준 연구", Korean Journal of Clinical Psychology, 28(2), pp.549~562 (2009), 한국임상심리학회[DOI]
- Bertola L, "Graph analysis of verbal fluency test discriminate between patients with Alzheimer’s disease, mild cognitive impairment and normal elderly controls", Front Aging Neurosci, 6, pp.185~ (2014)
- Woods SP, "Action(verb)fluency : test-retest reliability, normative standards, and construct validity", J Int Neuropsychol Soc, 11, pp.408~415 (2005)
- Arbuthnott K, "Trail making test, part B as a measure of executive control : validation using a set-switching paradigm", J Clin Exp Neuropsychol, 22, pp.518~528 (2000)
- Kane MJ, "Working memory, attention control, and the N-back task : a question of construct validity", J Exp Psychol Learn Mem Cogn, 33, pp.615~622 (2007)
- Akhtar S, "Are people with mild cognitive impairment aware of the benefits of errorless learning?", Neuropsychol Rehabil, 16, pp.329~346 (2006)
- Schreiber M, "Cognitive plasticity in people at risk for dementia : optimising the testing-the-limits-approach", Aging Ment Health, 11, pp.75~81 (2007)
- Contreras-Somoza LM, "Usability and user experience of cognitive intervention technologies for elderly people with MCI or dementia : a systematic review", Front Psychol, 12, pp.636116~ (2021)
- Brum PS, "Cognitive training in older adults with Mild Cognitive Impairment : Impact on cognitive and functional performance", Dement Neuropsychol, 3, pp.124~131 (2009)
- Barnes DE, "Computer-based cognitive training for mild cognitive impairment : results from a pilot randomized, controlled trial", Alzheimer Dis Assoc Disord, 23, pp.205~210 (2009)
- Lee GJ, "A comparison of the effects between 2 computerized cognitive training programs, Bettercog and COMCOG, on elderly patients with MCI and mild dementia : A single-blind randomized controlled study", Medicine(Baltimore), 97, pp.e13007~ (2018)
- 한혜원, "기능성 게임의 개념적 정의와 유형", 인문콘텐츠, (19), pp.219~236 (2010), 인문콘텐츠학회
- Shahmoradi L, "A systematic review on serious games in attention rehabilitation and their effects", Behav Neurol, 2022, pp.2017975~ (2022)
- Wang R, "A systematic review of serious games in training health care professionals", Simul Healthc, 11, pp.41~51 (2016)
- Ning H, "A review on serious games for dementia care in ageing societies", IEEE J Transl Eng Health Med, 8, pp.1400411~ (2020)
- Abd-Alrazaq A, "The effectiveness and safety of serious games for improving cognitive abilities among elderly people with cognitive impairment : systematic review and meta-analysis", JMIR Serious Games, 10, pp.e34592~ (2022)
- Lau SY, "A framework and immersive serious game for mild cognitive impairment", Multimedia Tools Appl, 80, pp.31183~31237 (2021)
- Dietlein C, "Feasibility and effects of serious games for people with dementia : a systematic review and recommendations for future research", Gerontechnology(Valkenswaard), 17, pp.1~17 (2018)
- Ferreira-Brito F, "Are video games effective to promote cognition and everyday functional capacity in mild cognitive impairment", dementia patients? A meta-analysis of randomized controlled trials, 2021, pp.84, 329~341
- Zhao Y, "Effectiveness of exergaming in improving cognitive and physical function in people with mild cognitive impairment or dementia : systematic review", JMIR Serious Games, 8, pp.e16841~ (2020)
- 양영순, "Improvement of Cognitive Function after Computer-Based Cognitive Training in Early Stage of Alzheimer’s Dementia", Dementia and Neurocognitive Disorders(대한치매학회지), 16(1), pp.7~11 (2017), 대한치매학회[DOI]
- Thapa N, "The effect of a virtual reality-based intervention program on cognition in older adults with mild cognitive impairment : a randomized control trial", J Clin Med, 9, pp.1283~ (2020)
- Jahouh M, "Impact of an intervention with Wii video games on the autonomy of activities of daily living and psychological–cognitive components in the institutionalized elderly", Int J Environ Res Public Health, 18, pp.1570~ (2021)
- Robert P, "Efficacy of a web app for cognitive training(MeMo)regarding cognitive and behavioral performance in people with neurocognitive disorders : randomized controlled trial", J Med Internet Res, 22, pp.e17167~ (2020)
- Savulich G, "Cognitive training using a novel memory game on an iPad in patients with amnestic mild cognitive impairment(aMCI)", Int J Neuropsychopharmacol, 20, pp.624~633 (2017)
- Berlucchi G, "Brain plasticity and cognitive neurorehabilitation", Neuropsychol Rehabil, 21, pp.560~578 (2011)
- Irazoki E, "Technologies for cognitive training and cognitive rehabilitation for people with mild cognitive impairment and dementia. A systematic review", Front Psychol, 11, pp.648~ (2020)
