Effects of gamma aminobutyric acid on performance, blood cell of broiler subjected to multi-stress environments
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective: Stress factors such as high temperatures, overcrowding, and diurnal temperature range exert profound negative effects on weight gain and productivity of broiler chickens. The potential of gamma aminobutyric acid (GABA) as an excitatory neurotransmitter was evaluated under various stress conditions in this study. Methods: The experiment was conducted under four different environmental conditions: normal, high temperature, overcrowded, and in an overcrowded-diurnal temperature range. The experimental groups were divided into (–) control group without stress, (+) control group with stress, and G50 group (GABA 50 mg/kg) with stress. Weight gain, feed intake, and feed conversion ratio were measured, and stress reduction was evaluated through hematologic analysis. Results: The effects of GABA on broilers in four experimental treatments were evaluated. GABA treated responded to environmental stress and improved productivity in all the experimental treatments. The magnitude of stress observed was highest at high temperature, followed by the overcrowded environment, and was least for the overcrowded-diurnal temperature range. Conclusion: Various stress factors in livestock rearing environment can reduce productivity and increase disease incidence and mortality rate. To address these challenges, GABA, an inhibitory neurotransmitter, was shown to reduce stress caused due to various environmental conditions and improve productivity.
Abstract
Objective: Stress factors such as high temperatures, overcrowding, and diurnal temperature range exert profound negative effects on weight gain and productivity of broiler chickens. The potential of gamma aminobutyric acid (GABA) as an excitatory neurotransmitter was evaluated under various stress conditions in this study. Methods: The experiment was conducted under four different environmental conditions: normal, high temperature, overcrowded, and in an overcrowded-diurnal temperature range. The experimental groups were divided into (–) control group without stress, (+) control group with stress, and G50 group (GABA 50 mg/kg) with stress. Weight gain, feed intake, and feed conversion ratio were measured, and stress reduction was evaluated through hematologic analysis. Results: The effects of GABA on broilers in four experimental treatments were evaluated. GABA treated responded to environmental stress and improved productivity in all the experimental treatments. The magnitude of stress observed was highest at high temperature, followed by the overcrowded environment, and was least for the overcrowded-diurnal temperature range. Conclusion: Various stress factors in livestock rearing environment can reduce productivity and increase disease incidence and mortality rate. To address these challenges, GABA, an inhibitory neurotransmitter, was shown to reduce stress caused due to various environmental conditions and improve productivity.
참고문헌 (24)
- Strawford ML, "The effect of simulated cold weather transport on core body temperature and behavior of broilers", Poult Sci, 90, pp.2415~2424 (2011)[DOI]
- Borges SA, "Dietary electrolyte balance for broiler chickens exposed to thermoneutral or heat-stress environments", Poult Sci, 82, pp.428~435 (2003)[DOI]
- Kang S, "An acute, rather than progressive, increase in temperature-humidity index has severe effects on mortality in laying hens", Front Vet Sci, 7, pp.568903~ (2020)[DOI]
- Barrett NW, "Effects of acute and chronic heat stress on the performance, egg quality, body temperature, and blood gas parameters of laying hens", Poult Sci, 98, pp.6684~6692 (2019)[DOI]
- Hashimoto K, "The role of glutamate on the action of antidepressants", Prog Neuropsychopharmacol Biol Psychiatry, 35, pp.1558~1568 (2011)[DOI]
- Bernard C, "What is GABAergic inhibition? How is it modified in epilepsy?", Epilepsy, 41, pp.S90~S5 (2000)[DOI]
- Elhussiny MZ, "Central GABAA receptor mediates taurine-induced hypothermia and possibly reduces food intake in thermo-neutral chicks and regulates plasma metabolites in heat-exposed chicks", J Therm Biol, 98, pp.102905~ (2021)[DOI]
- Hayakawa K, "Effect of a γ-aminobutyric acid-enriched dairy product on the blood pressure of spontaneously hypertensive and normotensive Wistar–Kyoto rats", Br J Nutr, 92, pp.411~417 (2004)[DOI]
- Inoue K, "Blood-pressure-lowering effect of a novel fermented milk containing γ-aminobutyric acid(GABA)in mild hypertensives", Eur J Clin Nutr, 57, pp.490~495 (2003)[DOI]
- DiMicco JA, "The dorsomedial hypothalamus : a new player in thermoregulation", Am J Physiol Regul Integr Comp Physiol, 292, pp.R47~R63 (2007)[DOI]
- Park KB, "Cloning, sequencing and expression of a novel glutamate decarboxylase gene from a newly isolated lactic acid bacterium, Lactobacillus brevis OPK-3", Bioresour Tehcnol, 98, pp.312~319 (2007)[DOI]
- Pandurang LT, "Overcrowding stress management in broiler chicken with herbal antistressor", Iranian J Appl Anim Sci, 1, pp.49~55 (2011)
- Yahav S, "Blood system response of chickens to changes in environmental temperature", Poult Sci, 76, pp.627~633 (1997)[DOI]
- Maciel TES, "Performance evaluation of the Sysmex® XE-2100D automated hematology analyzer", J Bras Patol Med Lab, 50, pp.26~35 (2014)[DOI]
- Sahin K, "Effects of chromium, and ascorbic acid supplementation on growth, carcass traits, serum metabolites, and antioxidant status of broiler chickens reared at a high ambient temperature(32 C)", Nutr Res, 23, pp.225~238 (2003)[DOI]
- Zaman Q, "Effect of varying dietary energy and protein on broiler performance in hot climate", Anim Feed Sci Technol, 146, pp.302~312 (2008)[DOI]
- Sands J, "Broilers in heat stress conditions : effects of dietary manganese proteinate or chromium picolinate supplementation", J Appl Poult Sci, 8, pp.280~287 (1999)[DOI]
- Yan L, "Dietary glutamine supplementation improves structure and function of intestine of juvenile Jian carp(Cyprinus carpio var. Jian)", Aquaculture, 256, pp.389~394 (2006)[DOI]
- Xie LJ, "Effect of heat stress on the expression of GABA receptor mRNA in the HPG axis of Wenchang chickens", Rev Bras Cienc Avic, 18, pp.277~282 (2016)[DOI]
- Jonaidi H, "GABAergic control of food intake in the meat-type chickens", Physiol Behav, 76, pp.465~468 (2002)[DOI]
- Dai SF, "Effects of dietary glutamine and gamma-aminobutyric acid on performance, carcass characteristics and serum parameters in broilers under circular heat stress", Anim Feed Sci Technol, 168, pp.51~60 (2011)[DOI]
- Xu Y, "Effect of chronic heat stress on some physiological and immunological parameters in different breed of broilers", Poult Sci, 97, pp.4073~4082 (2018)[DOI]
- Altan Ö, "Effects of heat stress on some blood parameters in broilers", Turk J Vet Anim Sci, 24, pp.145~148 (2000)
- Moraes V, "Effect of environmental temperature during the first week of brooding period on broiler chick body weight, viscera and bone development", Rev Bras Cienc Avic, 4, pp.1~8 (2002)[DOI]