Glutamine-supplement Diet Maintains Growth Performance and Reduces Blood Corticosterone Level in Cage-reared Growing Chicks
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Supplementation with glutamine(Gln) has beneficial effects on intestinal and immune functions. Cage-reared chicks suffer from various stressors during early growth, but the effect of Glnsupplementation on growth performance and stress hormones is uncertain. We investigated theeffect of Gln on growth performance and blood corticosterone levels in Hyline chicks. Groupsof 3-day-old chicks were fed one of three diets: normal feed(CTL group), normal feedsupplemented with a low level of Gln, or normal feed supplemented with a high level of Gln. Growth and various physiological and biochemical parameters related to stress were assessed. Onday 30, after a 24-h fast, blood was analyzed for corticosterone and other parameters, includingglutamic oxaloacetic transaminase, gamma-glutamyl transpeptidase, total bilirubin, lactatedehydrogenase, total cholesterol, high-density lipoprotein cholesterol, blood urea nitrogen, bloodtotal protein, and inorganic phosphate. Growth performance was maintained in Gln supplementedgroups. The corticosterone level was decreased in the two groups receiving Gln supplementationcompared to the CTL, and all other humoral factors did not differ between the groups. Wesuggest that Gln supplementation is a safe and useful strategy for reducing the effects of stressin cage-reared chicks.
Abstract
Supplementation with glutamine(Gln) has beneficial effects on intestinal and immune functions. Cage-reared chicks suffer from various stressors during early growth, but the effect of Glnsupplementation on growth performance and stress hormones is uncertain. We investigated theeffect of Gln on growth performance and blood corticosterone levels in Hyline chicks. Groupsof 3-day-old chicks were fed one of three diets: normal feed(CTL group), normal feedsupplemented with a low level of Gln, or normal feed supplemented with a high level of Gln. Growth and various physiological and biochemical parameters related to stress were assessed. Onday 30, after a 24-h fast, blood was analyzed for corticosterone and other parameters, includingglutamic oxaloacetic transaminase, gamma-glutamyl transpeptidase, total bilirubin, lactatedehydrogenase, total cholesterol, high-density lipoprotein cholesterol, blood urea nitrogen, bloodtotal protein, and inorganic phosphate. Growth performance was maintained in Gln supplementedgroups. The corticosterone level was decreased in the two groups receiving Gln supplementationcompared to the CTL, and all other humoral factors did not differ between the groups. Wesuggest that Gln supplementation is a safe and useful strategy for reducing the effects of stressin cage-reared chicks.
참고문헌 (43)
- Baccan GC, "Stress and immunological phagocytosis: possible nongenomic action of corticosterone", Life Sci., 75, pp.1357~1368 (2004)[DOI]
- Borsoi A, "Effects of cold stress and Salmonella Heidelberg infection on bacterial load and immunity of chickens", Avian Pathol., 44, pp.490~497 (2015)[DOI]
- Bowtell JL, "Effect of oral glutamine on whole body carbohydrate storage during recovery from exhaustive exercise", J. Appl. Physiol., 86, pp.1770~1777 (1999)[DOI]
- Brantsaeter M, "Exposure to Increased Environmental Complexity during Rearing Reduces Fearfulness and Increases Use of Three-Dimensional Space in Laying Hens(Gallus gallus domesticus)", Front. Vet. Sci., 3, pp.14~ (2016)
- Campbell JW, "Metabolic compartmentation of vertebrate glutamine synthetase: putative mitochondrial targeting signal in avian liver glutamine synthetase", Mol. Bio. Evol., 9, pp.787~805 (1992)
- Carey JB, "Effects of pullet-stocking density on performance of laying hens", Poult. Sci., 66, pp.1283~1287 (1987)[DOI]
- Cheng HW, "Chronic social stress differentially regulates neuroendocrine responses in laying hens: II. Genetic basis of adrenal responses under three different social conditions", Psychoneuroendocrinology, 29, pp.961~971 (2004)[DOI]
- 최양호, "가금 생산에서 스트레스의 관리", 한국가금학회지, 34(4), pp.295~300 (2007), 한국가금학회
- Dennis RA, "Immune function and muscle adaptations to resistance exercise in older adults: Study protocol for a randomized controlled trial of a nutritional supplement", Trials, 16, pp.121~ (2015)[DOI]
- Duan Y, "Cholesterol deregulation induced by chronic corticosterone(CORT) stress in pectoralis major of broiler chickens", Comp. Biochem. Physiol. Mol. Integr. Physiol., 176, pp.59~64 (2014)[DOI]
- El-Gohary FA, "Environmental augmentation with bacteriophage prevents colibacillosis in broiler chickens", Poult. Sci., 93, pp.2788~2792 (2014)[DOI]
- Fraisse F, "Corticosterone and fear behaviour in white and brown caged laying hens", Br. Poult. Sci., 47, pp.110~119 (2006)[DOI]
- Fu W, "Comparative proteomic analysis of the breast muscle response to chronic corticosterone administration in broiler chickens showing long or short tonic immobility", Poult. Sci., 93, pp.784~793 (2014)[DOI]
- Gawronski JD, "Microtiter assay for glutamine synthetase biosynthetic activity using inorganic phosphate detection", Anal. Biochem., 327, pp.114~118 (2004)[DOI]
- Gomes AV, "Overcrowding stress decreases macrophage activity and increases Salmonella Enteritidis invasion in broiler chickens", Avian Pathol., 43, pp.82~90 (2014)[DOI]
- Harrison GJ, "Clinical avian medicine. Avian Medicine Online by Harrison's Bird Foods" (2006)
- Hertz L, "Acute and chronic effects of antidepressant drugs on beta-adrenergic function in astrocytes in primary cultures: an indication of glial involvement in affective disorders?", J. Neurosci. Res., 9, pp.173~182 (1983)[DOI]
- Huang Y, "Glutamine directly downregulates glutamine synthetase protein levles in mouse C2C12 skeletal muscle myotubes", J. Nutr., 137, pp.1357~1362 (2007)[DOI]
- Joo Y, "Chronic immobilization stress induces anxiety- and depression-like behaviors and decreases transthyretin in the mouse cortex", Neurosci. Lett., 461, pp.121~125 (2009)[DOI]
- Jung S, "Decreased levels of RGS4 in the paraventricular nucleus facilitate GABAergic inhibition during the acute stress response", Biochem. Biophys. Res. Commun., 472, pp.276~280 (2016)[DOI]
- 김경화, "The GABAB receptor associates with regulators of G-protein signaling 4 protein in the mouse prefrontal cortex and hypothalamus", BMB Reports, 47(6), pp.324~329 (2014), 생화학분자생물학회
- Kim J, "Differential abundance of egg white proteins in laying hens treated with corticosterone", J. Agric. Food Chem., 62, pp.12346~12359 (2014)[DOI]
- Lay DC Jr, "Hen welfare in different housing systems", Poult. Sci., 90, pp.278~294 (2011)[DOI]
- Lee Y, "Glutamine deficiency in the prefrontal cortex increases depressive-like behaviours in male mice", J. Psychiatry Neurosci., 38, pp.183~191 (2013)[DOI]
- Limami AM, "Genetic and physiological analysis of germination efficiency in maize in relation to nitrogen metabolism reveals the importance of cytosolic glutamine synthetase", Plant Physiol., 130, pp.1860~1870 (2002)[DOI]
- Lin H, "Oxidative stress induced by corticosterone administration in broiler chickens(Gallus gallus domesticus) 2. Shortterm effect", Com. Biochem. Physiol. B Biochem. Mol. Biol., 139, pp.745~751 (2004)[DOI]
- Maruyama K, "Is L-glutamic acid nutritionally a dispensable amino acid for the young chick?", Poult. Sci., 55, pp.45~60 (1976)[DOI]
- Meijer GA, "Free amino acids in plasma and muscle of high yielding dairy cows in early lactation", J. Dairy Sci., 78, pp.1131~1141 (1995)[DOI]
- Park JY, "Characterization of Clostridium perfringens isolates obtained from 2010 to 2012 from chickens with necrotic enteritis in Korea", Poult. Sci., 94, pp.1158~1164 (2015)[DOI]
- Patejunas G, "Tissue-specific regulation of avian glutamine synthetase expression during development and in response to glucocorticoid hormones", Mol. Cell Biol., 7, pp.1070~1077 (1987)[DOI]
- Rettenbacher S, "Corticosterone in chicken eggs", Ann. N. Y. Acad. Sci., 1046, pp.193~203 (2005)[DOI]
- Santos AC, "Intravenous Glutamine Administration Modulates TNF-alpha", IL-10 Ratio and Attenuates NFkB Phosphorylation in a Protein Malnutrition Model, 2016, pp.39, 1883~1891
- Sapolsky RM, "How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions", Endocrine Rev., 21, pp.55~89 (2000)
- Sasaguri K, "Stress-induced galectin-1 influences immune tolerance in the spleen and thymus by modulating CD45 immunoreactive lymphocytes", J. Physiol. Sci., 67, pp.489~496 (2016)
- Shini S, "Effects of stress, mimicked by administration of corticosterone in drinking water, on the expression of chicken cytokine and chemokine genes in lymphocytes", Stress, 12, pp.388~399 (2009)[DOI]
- Simi S, "Zymosan-induced immune challenge modifies the stress response of hypoxic air-breathing fish(Anabas testudineus Bloch): Evidence for reversed patterns of cortisol and thyroid hormone interaction, differential ion transporter functions and non-specific immune response", Gen. Comp. Endocrinol., 251, pp.94~108 (2016)
- 손시환, "계사 사육 형태가 산란계의 생산성과 스트레스 반응에 미치는 영향", 한국가금학회지, 38(4), pp.305~313 (2011), 한국가금학회
- Son H, "Type 1 diabetes alters astrocytic properties related with neurotransmitter supply, causing abnormal neuronal activities", Brain Res., 1602, pp.32~43 (2015)[DOI]
- Sun X, "Effects of heat stress on the gene expression of nutrient transporters in the jejunum of broiler chickens(Gallus gallus domesticus)", Int. J. Biometeorol., 59, pp.127~135 (2015)[DOI]
- Watford M, "Glutamine and glutamate: Nonessential or essential amino acids?", Animal Nutrition, 1, pp.119~122 (2015)[DOI]
- Willems E, "Reduced protein availability by albumen removal during chicken embryogenesis decreases body weight and induces hormonal changes", Exp. Physiol., 100, pp.1298~1308 (2015)[DOI]
- Young LS, "Patients receiving glutamine-supplemented intravenous feedings report an improvement in mood", JPEN J. Parenter. Enteral Nutr., 17, pp.422~427 (1993)[DOI]