본문 바로가기
KERD
논문KCI 등재

The Effect of Temperament on the Association Between Pre-treatment Anxiety and Chemotherapy-Related Symptoms in Patients With Breast Cancer

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류정신과학

초록

Objective Pre-treatment anxiety (PA) before chemotherapy increases complaints of chemotherapy-related symptoms (CRS). The results on the association have been inconsistent, and the effect of temperament remains unclear. We aimed to determine whether PA is a risk factor for CRS and the effect of differing temperaments on CRS.Methods This prospective study comprised 176 breast cancer patients awaiting adjuvant chemotherapy post-surgery. We assessed CRS, PA, and temperament using the MD Anderson Symptom Inventory (MDASI), the Hospital Anxiety and Depression Scale, and the short form of the Temperament and Character Inventory-Revised, respectively. The MDASI was re-administered three weeks after the first chemo-cycle.Results PA showed weak positive correlation with several CRS after the first cycle; no CRS was significantly associated with PA when pre-treatment depressive symptoms and baseline CRS were adjusted in multiple regression analysis. Moderation model analysis indicated that the PA effect on several CRS, including pain, insomnia, anorexia, dry mouth, and vomiting, was moderated by harm avoidance (HA) but not by other temperament dimensions. In particular, PA was positively associated with CRS in patients with low HA.Conclusion The results in patients with low HA indicate that more attention to PA in patients with confident and optimistic temperaments is necessary.

Abstract

Objective Pre-treatment anxiety (PA) before chemotherapy increases complaints of chemotherapy-related symptoms (CRS). The results on the association have been inconsistent, and the effect of temperament remains unclear. We aimed to determine whether PA is a risk factor for CRS and the effect of differing temperaments on CRS.Methods This prospective study comprised 176 breast cancer patients awaiting adjuvant chemotherapy post-surgery. We assessed CRS, PA, and temperament using the MD Anderson Symptom Inventory (MDASI), the Hospital Anxiety and Depression Scale, and the short form of the Temperament and Character Inventory-Revised, respectively. The MDASI was re-administered three weeks after the first chemo-cycle.Results PA showed weak positive correlation with several CRS after the first cycle; no CRS was significantly associated with PA when pre-treatment depressive symptoms and baseline CRS were adjusted in multiple regression analysis. Moderation model analysis indicated that the PA effect on several CRS, including pain, insomnia, anorexia, dry mouth, and vomiting, was moderated by harm avoidance (HA) but not by other temperament dimensions. In particular, PA was positively associated with CRS in patients with low HA.Conclusion The results in patients with low HA indicate that more attention to PA in patients with confident and optimistic temperaments is necessary.

참고문헌 (40)

  1. Fernández-Ortega P, "Chemotherapy-induced nausea and vomiting in clinical practice: impact on patients’ quality of life", Support Care Cancer, 20, pp.3141~3148 (2012)
  2. Partridge AH, "Adherence and persistence with oral adjuvant chemotherapy in older women with early-stage breast cancer in CALGB 49907: adherence companion study 60104", J Clin Oncol, 28, pp.2418~2422 (2010)
  3. Griffin AM, "On the receiving end. V: patient perceptions of the side effects of cancer chemotherapy in 1993", Ann Oncol, 7, pp.189~195 (1996)
  4. Hoang HTX, "New-onset insomnia among cancer patients undergoing chemotherapy:prevalence, risk factors, and its correlation with other symptoms", Sleep Breath, 24, pp.241~251 (2020)
  5. Ho SY, "A longitudinal study of depression, fatigue, and sleep disturbances as a symptom cluster in women with breast cancer", J Pain Symptom Manage, 49, pp.707~715 (2015)
  6. Ancoli-Israel S, "The relationship between fatigue and sleep in cancer patients: a review", Eur J Cancer Care (Engl), 10, pp.245~255 (2001)
  7. Schneider A, "Trajectories and predictors of state and trait anxiety in patients receiving chemotherapy for breast and colorectal cancer: results from a longitudinal study", Eur J Oncol Nurs, 24, pp.1~7 (2016)
  8. Jacobsen PB, "Anticipatory anxiety in women receiving chemotherapy for breast cancer", Health Psychol, 12, pp.469~475 (1993)
  9. Watson M, "Psychological factors predicting nausea and vomiting in breast cancer patients on chemotherapy", Eur J Cancer, 34, pp.831~837 (1998)
  10. Molassiotis A, "Pretreatment factors predicting the development of postchemotherapy nausea and vomiting in Chinese breast cancer patients", Support Care Cancer, 10, pp.139~145 (2002)
  11. Grassi L, "Role of psychosocial variables on chemotherapy-induced nausea and vomiting and health-related quality of life among cancer patients: a European study", Psychother Psychosom, 84, pp.339~347 (2015)
  12. Whitford HS, "When expectations predict experience: the influence of psychological factors on chemotherapy toxicities", J Pain Symptom Manage, 43, pp.1036~1050 (2012)
  13. Lockefeer JP, "What is the relationship between trait anxiety and depressive symptoms, fatigue, and low sleep quality following breast cancer surgery?", Psychooncology, 22, pp.1127~1133 (2013)
  14. Van Esch L, "Trait anxiety predicts disease-specific health status in early-stage breast cancer patients", Qual Life Res, 20, pp.865~873 (2011)
  15. Molassiotis A, "Development and preliminary validation of a risk prediction model for chemotherapy-related nausea and vomiting", Support Care Cancer, 21, pp.2759~2767 (2013)
  16. Yun YH, "Validation study of the Korean version of the M. D. Anderson Symptom Inventory", J Pain Symptom Manage, 31, pp.345~352 (2006)
  17. Mendoza TR, "The validity and utility of the M. D. Anderson Symptom Inventory in patients with breast cancer: evidence from the symptom outcomes and practice patterns data from the eastern cooperative oncology group", Clin Breast Cancer, 13, pp.325~334 (2013)
  18. Kautio AL, "Amitriptyline in the treatment of chemotherapy-induced neuropathic symptoms", J Pain Symptom Manage, 35, pp.31~39 (2008)
  19. Zigmond AS, "The hospital anxiety and depression scale", Acta Psychiatr Scand, 67, pp.361~370 (1983)
  20. Oh SM, "A comparison of normal, depressed and anxious groups: a study on the standardization of the hospital anxiety and depressed scale for Koreans", J Korean Neuropsychiatr Assoc, 38, pp.289~296 (1999)
  21. Bjelland I, "The validity of the hospital anxiety and depression scale: an updated literature review", J Psychosom Res, 52, pp.69~77 (2002)
  22. Cloninger CR, "The temperament and character inventory (TCI): a guide to its development and use", Washington University, ~ (1994)
  23. Goth K, "Das Temperament und Charakter Inventar Kurzversion für Erwachsene - TCI R Kurz", JW Goethe University, ~ (2003)
  24. Cloninger CR, "A psychobiological model of temperament and character", Arch Gen Psychiatry, 50, pp.975~990 (1993)
  25. Heath AC, "Testing a model for the genetic structure of personality: a comparison of the personality systems of Cloninger and Eysenck", J Pers Soc Psychol, 66, pp.762~775 (1994)
  26. Marchesi C, "Effect of pharmacological treatment on temperament and character in panic disorder", Psychiatry Res, 158, pp.147~154 (2008)
  27. Boz C, "Effect of serotonergic antidepressant therapy on temperament and character scales in patients with chronic tension-type headache", Psychiatry Clin Neurosci, 61, pp.534~542 (2007)
  28. Hirano S, "Evaluating the state dependency of the temperament and character inventory dimensions in patients with major depression: a methodological contribution", J Affect Disord, 69, pp.31~38 (2002)
  29. Peirson AR, "The relationship between personality and mood: comparison of the BDI and the TCI", Pers Individ Differ, 30, pp.391~399 (2001)
  30. Hayes AF, "Introduction to mediation, moderation, and conditional process analysis: a regression-based approach" (2013), Guilford Press
  31. Aiken LS, "Multiple regression: testing and interpreting interactions" (1991), Sage
  32. Dranitsaris G, "The development of a prediction tool to identify cancer patients at high risk for chemotherapy-induced nausea and vomiting", Ann Oncol, 28, pp.1260~1267 (2017)
  33. Cloninger CR, "A unified biosocial theory of personality and its role in the development of anxiety states", Psychiatr Dev, 4, pp.167~226 (1986)
  34. Clarke P, "Prepared for the worst: readiness to acquire threat bias and susceptibility to elevate trait anxiety", Emotion, 8, pp.47~57 (2008)
  35. Wirtz PW, "Anxiety effects on disaster precautionary behaviors: a multi-path cognitive model", J Health Psychol, 24, pp.1401~1411 (2019)
  36. Van Der Pligt J, "Perceived risk and vulnerability as predictors of precautionary behaviour", Br J Health Psychol, 3, pp.1~14 (1998)
  37. Schwarzer R, "Optimism, vulnerability, and self-beliefs as health-related cognitions: a systematic overview", Psychol Health, 9, pp.161~180 (1994)
  38. Jovančević A, "Optimism-pessimism, conspiracy theories and general trust as factors contributing to COVID-19 related behavior - A cross-cultural study", Pers Individ Dif, 167, pp.110216~ (2020)
  39. Min BB, "Temperament and character inventory-family manual" (2007), Maumsarang
  40. Ream E, "The role of information in patients’ adaptation to chemotherapy and radiotherapy: a review of the literature", Eur J Cancer Care (Engl), 5, pp.132~138 (1996)

관련 논문AI추천

스트레스, 불안, 우울 및 인격특성이 항암화학요법 시행 중인 유방암 환자들의 오심, 구역, 구토에 미치는 영향문병인, 반유화, 백남선, 임우성, 임원정, 최희연대한신경정신의학회 · 신경정신의학2013 · 제52권 제5호Avoidant Insecure Attachment as a Predictive Factor for Psychological Distress in Patients with Early Breast Cancer: A Preliminary 1-Year Follow-Up StudyHyo-Deog Rim, Jungmin Woo, Sang-Shin Lee, Seung-Hee Won대한신경정신의학회 · PSYCHIATRY INVESTIGATION2018 · 제15권 제8호Anxiety and Depression as Predictive Factors for Quality of Life in Patients with Advanced Gastrointestinal Cancer권지현, 김승택, 김현경, 정정화, 주가원, 한혜숙대한종양간호학회 · Asian Oncology Nursing2016 · 제16권 제4호Insomnia, Anxiety, and Depression in Patients First Diagnosed With Female CancerHo Dham, Kim Soo In, Kim Sung-Youn, Kim Sun-Young, Lim Weon-Jeong대한신경정신의학회 · PSYCHIATRY INVESTIGATION2021 · 제18권 제8호Psychometric Properties of Assessment Tools for Depression, Anxiety, Distress, and Psychological Problems in Breast Cancer Patients: A Systematic ReviewKang Taewoo, Kim Kyoung-Eun, Moon Eunsoo, Park Heeseung대한신경정신의학회 · PSYCHIATRY INVESTIGATION2023 · 제20권 제5호Anxiety and Depression of the Patients with Hematological Malignancies during Hospitalization for Hematopoietic Stem Cell Transplantation엄유현, Byung-Sik Cho, Ho-Jun Seo, Jeong-Ho Chae, Tae-Suk Kim, Young-Gun Baek대한신경정신의학회 · PSYCHIATRY INVESTIGATION2019 · 제16권 제10호

이 간행물의 다른 논문 (10건)