Anxiety and Depression as Predictive Factors for Quality of Life in Patients with Advanced Gastrointestinal Cancer
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Purpose: The purpose of the present study was to assess factors associated with quality of life (QOL) and to determine whether anxiety and depression are predictive of QOL in patients with advanced gastrointestinal cancer at initial diagnosis and during the treatment process. Methods: One hundred and twenty patients with gastrointestinal cancer requiring palliative chemotherapy were enrolled. Results: At baseline, depression, performance status, and anxiety accounted for 55.0% (p<.001) of the variance in global health status score, depression accounted for 22.0% (p<.001) of the variance in functional scales score, and anxiety accounted for 19.0% (p<.001) of the variance in symptom scales score. At 3 months, depression, pain, and performance status accounted for 72.0% (p<.001) of the variance in global health status score, 76.0% (p<.001) of the variance in functional scales score, and 74.0% (p<.001) of the variance in symptom scales score. Conclusion: Anxiety and depression were significant predictive factors of QOL in patients with advanced gastrointestinal cancer. Depression and performance status were significant predictive factors of QOL at both baseline and 3 months, and anxiety and pain were significant predictive factors of QOL at baseline and 3 months, respectively.
Abstract
Purpose: The purpose of the present study was to assess factors associated with quality of life (QOL) and to determine whether anxiety and depression are predictive of QOL in patients with advanced gastrointestinal cancer at initial diagnosis and during the treatment process. Methods: One hundred and twenty patients with gastrointestinal cancer requiring palliative chemotherapy were enrolled. Results: At baseline, depression, performance status, and anxiety accounted for 55.0% (p<.001) of the variance in global health status score, depression accounted for 22.0% (p<.001) of the variance in functional scales score, and anxiety accounted for 19.0% (p<.001) of the variance in symptom scales score. At 3 months, depression, pain, and performance status accounted for 72.0% (p<.001) of the variance in global health status score, 76.0% (p<.001) of the variance in functional scales score, and 74.0% (p<.001) of the variance in symptom scales score. Conclusion: Anxiety and depression were significant predictive factors of QOL in patients with advanced gastrointestinal cancer. Depression and performance status were significant predictive factors of QOL at both baseline and 3 months, and anxiety and pain were significant predictive factors of QOL at baseline and 3 months, respectively.
참고문헌 (30)
- "Surveillance, epidemiology, and end results program"[URL]
- 오창모, "Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2013", Cancer Research and Treatment, 48(2), pp.436~450 (2016), 대한암학회
- 정규원, "Prediction of Cancer Incidence and Mortality in Korea, 2016", Cancer Research and Treatment, 48(2), pp.451~457 (2016), 대한암학회
- "Cancer Statistics in Korea"[URL]
- Polanski J, "Quality of life of patients with lung cancer", Onco Targets Ther, 9, pp.1023~1028 (2016)
- van Nieuwenhuizen AJ, "The association between health related quality of life and survival in patients with head and neck cancer : a systematic review", Oral Oncol, 51(1), pp.1~11 (2015)
- Svensson H, "Healthrelated quality of life as prognostic factor for response, progression-free survival, and survival in women with metastatic breast cancer", Med Oncol, 29(2), pp.432~438 (2012)
- Temel JS, "Early palliative care for patients with metastatic non-small-cell lung cancer", N Engl J Med, 363(8), pp.733~742 (2010)
- Pirl WF, "Depression and survival in metastatic non-small-cell lung cancer : effects of early palliative care", J Clin Oncol, 30(12), pp.1310~1315 (2012)
- Giese-Davis J, "Decrease in depression symptoms is associated with longer survival in patients with metastatic breast cancer : a secondary analysis", J Clin Oncol, 29(4), pp.413~420 (2011)
- Pinquart M, "Depression and cancer mortality : a metaanalysis", Psychol Med, 40(11), pp.1797~1810 (2010)
- Gil F, "First anxiety, afterwards depression : psychological distress in cancer patients at diagnosis and after medical treatment", Stress Health, 28(5), pp.362~367 (2012)
- Annunziata MA, "Psychological distress and needs of cancer patients : a prospective comparison between the diagnostic and the therapeutic phase", Support Care Cancer, 19(2), pp.291~295 (2010)
- Andersen BL, "American Society of Clinical Oncology. Screening, assessment, and care of anxiety and depressive symptoms in adults with cancer: an American Society of Clinical Oncology guideline adaptation", J Clin Oncol, 32(15), pp.1605~1619 (2014)
- Bužgová R, "Assessing anxiety and depression with respect to the quality of life in cancer inpatients receiving palliative care", Eur J Oncol Nurs, 19(6), pp.667~672 (2015)
- Montazeri A, "Quality of life data as prognostic indicators of survival in cancer patients : an overview of the literature from 1982 to 2008", Health Qual Life Outcomes, 7, pp.102~ (2009)
- Slovacek L, "Quality of life and depression among metastatic breast cancer patients", Med Oncol, 27(3), pp.958~959 (2010)
- Tavoli A, "Deression and quality of life in cancer patients with and without pain : the role of pain beliefs", BMC Cancer, 8, pp.177~ (2008)
- Matsushita T, "Psychological state, quality of life, and coping style in patients with digestive cancer", Gen Hosp Psychiatry, 27(2), pp.125~132 (2005)
- Alacacioglu A, "Quality of life, anxiety, and depression in Turkish colorectal cancer patients", Support Care Cancer, 18(4), pp.417~421 (2010)
- Oken MM, "Toxicity and response criteria of the Eastern Cooperative Oncology Group", Am J Clin Oncol, 5(6), pp.649~655 (1982)
- Yun YH, "Validation of the Korean version of the EORTC QLQ-C30", Qual Life Res, 13(4), pp.863~868 (2004)
- Fard JH, "Quality of life and its related factors among Iranian patients with metastatic gastrointestinal tract cancer : a cross-sectional study", Indian J Palliat Care, 20(3), pp.215~219 (2014)
- Oh SM, "A study on the standardization of the hospital anxiety and depression scale for Koreans-A comparison of normal, depressed and anxious groups", J Korean Neuropsychiatr Assoc, 38(2), pp.289~296 (1999)
- Shim EJ, "Distress and its correlates in Korean cancer patients : pilot use of the distress thermometer and the problem list", Psychooncology, 17(6), pp.548~555 (2008)
- Kim SJ, "Prevalence and associated factors of psychological distress among Korean cancer patients", Gen Hosp Psychiatry, 33(3), pp.246~252 (2011)
- Tsunoda A, "Anxiety, depression and quality of life in colorectal cancer patients", Int J Clin Oncol, 10(6), pp.411~417 (2005)
- van den Beuken-van Everdingen MH, "Prevalence of pain in patients with cancer : a systematic review of the past 40 years", Ann Oncol, 18(9), pp.1437~1449 (2007)
- Green CR, "Cancer-related chronic pain : examining quality of life in diverse cancer survivors", Cancer, 117(9), pp.1994~2003 (2011)
- Tachi T, "The impact of outpatient chemotherapy-related adverse events on the quality of life of breast cancer patients", PLoS One, 10(4), pp.e0124169~ (2015)
