12주 걷기 운동이 공복시 혈당장애 여성의 인슐린 감수성에 미치는 영향
The effects of 12-week walking training on insulin sensitivity in postmenopausal female with impaired fasting glucose
2
조회
0
다운로드
8
인용
0
참고문헌
키워드
초록
12주 걷기 운동이 공복시 혈당장애 여성의 인슐린 감수성에 미치는 영향. 운동과학, 13(4): 435-444, 2004. 본 연구의 목적은 12주간의 규칙적인 신체활동이 공복시 혈당장애를 가진 폐경기 여성들의 인슐린 감수성에 미치는 영향을 알아보는 것이다. 자발적으로 참여한 피험자들중 공복시 혈당수준이 100 mg/dl 이상인 11명을 선별하여 연구를 실시하였다. 모든 피험자들은 12주간 주당 4일의 걷기 또는 빠르게 걷기 운동을 실시하였고 이들이 1일 걸은 거리를 매일 측정하여 기록하였다. 75-g 경구혈당부하검사와 최대산소섭취량, 신체계측, 혈중 지질, 그리고 HbA1c 수준은 운동전, 6주, 12주 운동후 측정하였다. 12주간의 운동으로 체중의 변화는 나타나지 않았으나 최대산소섭취량의 수준은 유의하게 증가한 것으로 나타났다(0-wk; 22.6±0.5 < 6-wk; 24.2±0.8 < 12-wk; 25.4 ±0.9 ㎖/㎏/min, p<.05). 경구혈당주하검사시 혈당과 인슐린, c-peptide 수준은 12주간 유의한 변화가 나타나지 않았다. 또한 혈중 지질의 수준도 유의한 변화가 나타나지 않았다. 그러나 HbA1c 수준은 유의하게 감소하였다 (0-wk; 6.0±0.1 < 6-wk; 5.65±0.1 < 12-wk; 5.6±0.1 % p<.05). 따라서 1일 20 km 미만의 걷기운동은 공복시 혈당장애를 가진 폐경기 여성의 HbA1c 수준에는 유의한 영향을 미치나 신체구성과 혈중지질 그리고 인슐린 감수성에 영향을 미치지는 못하는 것으로 사료된다.
Abstract
The effects of 12-week walking training on insulin sensitivity in postmenopausal female with impaired fasting glucose. Exercise Science, 13(4): 435-444, 2004. The purpose of this study was to examine the impacts of 12-week physical training on insulin sensitivity in postmenopausal female with impaired fasting glucose (IFG). 11- postmenopausal women were volunteered for this study and their fasting blood glucose levels were over 100 ㎎/㎗. All subjects were asked voluntarily to walk/fast walk 4 days of each week for 12 weeks on treadmill and the walk/fast walk distance were recorded. The 75 g oral glucose tolerance test (OGTT), VO₂max and blood sampling were performed at prior to training (0-wks), 6-week (6-wks) and 12-week (12-wks) after training. Blood lipids and HbA1c were measured from collected blood samples. VO₂max was significantly improved after 6-week (24.2±0.8 ㎖/㎏/min) and 12-week (25.4 ±0.9 ㎖/㎏/min) training compared to baseline (22.6±0.5 ㎖/㎏/min), respectively. Glucose, insulin and c-peptide responses in OGTT were not significantly different in 6-wks and 12-wks after training compared to 0-wks. The Plasma lipid profiles were not affected by training, but HbA1c in 6-wks (5.65±0.1 %) and 12-wks (5.6±0.1 %) were significantly different from 0-wks (6.0±0.1 %). Therefore, these data suggest that 12-week physical training in postmenopausal women with IFG may enhance the HbA1c level, but without the improvement of insulin sensitivity.
참고문헌 (26)
- "Effect of agingon response to exercise training in human skeletal muscle GHLUT-4 and insulin sensitivity", 86, pp.2019~2025 (1999)
- "Pathogenesis of NIDDM", pp.318~68 (1992)
- "Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men", 81, pp.318~25 (1996)
- "The insulin resistance- dyslipidemic syndrome of visceral obesity effect on patients' risk", 1, pp.6~ (1998)
- "Loss of abdominal fat and metabolic response to exercise training in obese women", pp.~67 (1991)
- "Exercise training, without weight loss,increases insulin sensitivity and postheparin plasma lipase activity in previously sedentary adults", 26, pp.557~62 (2003)
- "Prevention of type 2 diabetes mellitus by diet and physical exercise", (n-insulin- dependent), pp.891~34 8 (1991)
- "Estimation of the concentration of low-density lipoprotein cholesterol in plasma without use of preparative ultracentrifugation", pp.499~509 (1972)
- "Effects on glucose tolerance insulin secretion insulin-like growth factor 1 and its binding protein, IGFBP-1,in a randomized controlled diet and exercise study in healthy middle-aged men", 238, pp.121~1 30 (1995)
- "Effects of exercise on glucose tolerance and insulin resistance", pp.55~65 (1986)
- "Exercise training inceeases GLUT-4 concentration in previously sedentary middle-aged men" (1993)
- "Effect of exercise on insulin action and insulin secretion in aging", pp.~43 (1990)
- "Endurance exercise training reduces glucose-stimulated insulin levels in 60- to 70-year-old men and women", pp.~90 (1993)
- "Insulin resistance in aging is related to abdominal obesity", pp.273~81 (1993)
- "Effect of exercise training on glucose tolerance lipid and lipoprotein concentrations in middle-aged men with mild hypertriglyceridemia", pp.205~11 (1985)
- "Intensity and amount of physical activity in relation to insulin sensitivity the Insulin Resistance Atherosclerosis Study", 279, pp.669~74 (1998)
- "Aerobic circuit exercise training effect on adolescents with well-controlled insulin- dependent diabetes mellitus", 79(6), pp.652~7 (1998)
- "Abdominal obesity is associated with insulin resistance and reduced glycogen synthetase activity in skeletal muscle", pp.998~42 1005 (1993)
- "Contribution of obesity to insulin resistance in noninsulin- dependent diabetes mellitus", 80, pp.2464~9 (1995)
- "Changes in energy balance & body composition at menopause a controlled longitudinal study", 123, pp.673~5 (1995)
- "Effects of endurance training on glucose tolerance and plasma lipid levels in older men and women", pp.645~9 (1984)
- "Impact of Aerobic Exercise Training on Age-Related Changes in Insulin Sensitivity and Muscle Oxidative Capacity", 52, pp.1888~1896
- "Effects of the menopause transition on body fatness and body fat distribution", 6(f), pp.246~54 (1998)
- "Effect of physical training on the insulin resistance of aging", 256, pp.~6 (1989)
- "Policies and procedures of a cardiac rehabilitation program-Immediate to long term care" (1978), Lea & Febiger
- "Exercise training has little effect on HDL levels and metabolism in men with initially low HDL cholesterol", 137, pp.215~21 (1998)