12주 걷기 운동이 폐경 후 비만 여성의 식욕조절 호르몬, 아디포카인 및 인슐린 저항성에 미치는 영향
Effects of 12-weeks walking exercise on appetite regulating hormone, adipokine and insulin resistance in postmenopausal obesity women
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본연구의 목적은 12주간의 걷기운동이 폐경 후 비만 여성의식욕조절 호르몬, 아디토카인 및 인슐린 저항성에 미치는 영향을 알아보는데 있다. 연구 대상자는 폐경 후 비만 여성 15명(체지방률; 30.8±1.6%, 체질량지수; 26.3±0.8)을 대상으로 하였으며, 운동 프로그램은 트레드밀 걷기 (하루 5 km, 6회/주, 12주)를 실시하였다. 연구 대상자는 운동 전·후 혈액을 채취하고, 혈중지질, 혈당, 인슐린, 렙틴, 그렐린, HOMA-IR, TNF-α을분석하였다. 그 결과 최대산소섭취량은 운동 후 유의하게 증가하였으며 (p<.05), 체지방률은 감소한 것으로 나타났다(p<0.05).혈당, 인슐린 및 HOMA-IR은 12주 5 km 걷기 후 유의하게 감소한 것으로 나타났다 (p<.05). 혈중 렙틴은 운동 후 유의하게 감소하였며 (p<.05), 혈중 그렐린은 12주 걷기 운동 후 유의하게 증가한 것으로 나타났다 (p<.05). 반면 TNF-α는 유의한 차이가 없는 것으로 나타났다. 이상 본 연 구결과를 종합해 보면, 폐경 후 비만 여성의 12주 5 km 걷기 운동은 체지방률감소와 함께 인슐린 저항성(혈당, 인슐린, HOMA-IR), 혈중 그렐린과 렙틴을 개선시키는데 효과가 있는 것을 알 수 있었다.
Abstract
The purpose of this study was to investigate the effects of 12-weeks walking exercise on appetite regulating hormone, adipokine and insulin resistance in postmenopausal obesity women. The 15 postmenopausal obesity women (%fat; 30.8±1.6%, BMI; 26.3±0.8) were volunteered for this study, and experimental exercise protocol was treadmill walking (5 km/day, 6 day/week, 12 weeks). Blood sample were drawn before and after 12 weeks exercise, and blood lipids, plasma glucose, insulin, leptin, ghrelin, HOMA-IR, TNF-α were measured. The maximal oxygen consumption was significantly increased after training (p<.05), and the %fat was significantly reduced after 12-weeks walking (p<.05). Plasma glucose, insulin levels and HOMA-IR were significantly reduced after 12-weeks 5 km walking (p<.05). Plasma leptin was significantly reduced after training (p<.05), and the plasma ghrelin levels was significantly increased after 12 weeks walking exercise (p<.05). TNF-α levels were not significantly changed after 12-weeks exercise. The results of this study indicate that 5 km walking exercise for 12 weeks significantly reduced %fat and attenuated insulin resistance. In addition, 5 km walking exercise of postmenopausal obesity women improved plasma leptin and ghrelin.
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