노인들의 장기간 유산소 운동 참여가 면역물질 변화에 미치는 영향
The effects of long-term aerobic training on immune system in older adult
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오상덕. 노인들의 장기간 유산소 운동 참여가 면역물질 변화에 미치는 영향. 운동과학, 14(1): 77-86, 2005. 본 연구는 6개월 이상 운동 참여에 따른 면역 효과를 제시하기 위해 연령(중년, 노인)과 운동참여 여부(비교군, 훈련군)에 따른 면역물질을 비교하였다. 또한 노인집단에서 비교군과 훈련군을 대상으로 일시적 운동자극(최대하 운동)에 의한 면역물질(호중구, 단핵구, CD4, CD8, NK-세포, IL-2, IFN-γ)의 변화를 분석하였다. 그 결과, 연령과 운동참여에 따른 안정시 호중구, 단핵구, CD4, CD8 수준은 유의한 차이가 없었지만, NK-세포, IL-2, IFN-γ은 비교군에 비해 훈련군에서 유의하게 높은 수준을 보였다. 한편 최대하 운동에 따른 비교군과 훈련군의 면역반응은 대부분의 항목에서 훈련군에 비해 비교군에서 운동 후 회복기(운동 후 60분)에 유의한 감소를 보였다. 결론적으로 노화 과정에서 장기간 유산소 운동 참여는 안정시 면역물질(NK-세포, IL-2, IFN-γ) 수준의 향상에 영향을 미칠 수 있다.
Abstract
Oh, S.D. The effects of long-term aerobic training on immune system in older adult. Exercise Science. 14(1): 77-86. 2005. The purpose of this study was to examine the effects of long-term aerobic training and sub-exercise treatment on the changes of neutrophils, monocyte, CD4, CD8, natural killer-cell(NK-cell), interleukin (IL-2), and interferone-r(IFN-r) concentration in older adult. Level of blood NK-cell, IL-2, IFN-γ significantly increased in training than control group. Also, level of blood neutrophils, monocyte, CD4, NK-cell, and IL-2 following sub-exercise were significantly increased at post-0 and decreased at post-60 min in control than training group. In conclusion, long-term aerobic training induced positive effects on the changes of immune system in the older adult. Also, the effect of long-term aerobic training was to play in defending of declined immune system caused by sub-exercise treatment.
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