메탄올 작업장 노출 평가에의 EU REACH 프로토콜 적용: Targeted Risk Assessment
The Application of an EU REACH Protocol to the Occupational Exposure Assessment of Methanol: Targeted Risk Assessment
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Background: The European Centre for Ecotoxicology and Toxicology of Chemicals’ Targeted Risk Assessment (ECETOC TRA) tool has been recognized by EU REACH as a preferred approach for calculating worker health risks from chemicals. Objectives: The applicability of the ECETOC TRA to occupational exposure estimation from industrial uses of methanol was studied by inputting surveyed and varied parameters for TRA estimation as well as through comparison with measured data. Methods: Information on uses of methanol was collected from seven working environment monitoring reports along with the measured exposure data. Input parameters for TRA estimation such as operating conditions (OCs), risk management measures (RMMs) and process categories (PROCs) were surveyed. To compare with measured exposures, parameters from the surveyed conditions of ventilation but no use of respiratory protection were applied. Results: PROCs 4, 5, 8a, 10, and 15 were assigned to ten uses of methanol. The uses include as a solvent for manufacturing sun cream, surfactants, dyestuffs, films and adhesives. Methanol was also used as a component in a release agent, hardening media and mold wash for cast products as well as a component of hard-coating solution and a viscosity-controlling agent for manufacturing glass lenses. PROC 8a and PROC 10 of a cast product manufacturer without LEV (local exhaust ventilation) and general ventilation as well as no respiratory protection resulted in the highest exposure to methanol. Assuming the identical worst OCs and RMMs for all uses, exposures from PROC 5, 8a, and 10 were the same and the highest followed by PROC 4 and 15. The estimation resulted in higher exposures in nine uses except one use where measured exposure approximated exposures without RMMs. Conclusions: The role of ECETOC TRA as a conservative exposure assessment tool was confirmed by comparison with measured data. Moreover, it can guide which RMMs should be applied for the safe use of methanol.
Abstract
Background: The European Centre for Ecotoxicology and Toxicology of Chemicals’ Targeted Risk Assessment (ECETOC TRA) tool has been recognized by EU REACH as a preferred approach for calculating worker health risks from chemicals. Objectives: The applicability of the ECETOC TRA to occupational exposure estimation from industrial uses of methanol was studied by inputting surveyed and varied parameters for TRA estimation as well as through comparison with measured data. Methods: Information on uses of methanol was collected from seven working environment monitoring reports along with the measured exposure data. Input parameters for TRA estimation such as operating conditions (OCs), risk management measures (RMMs) and process categories (PROCs) were surveyed. To compare with measured exposures, parameters from the surveyed conditions of ventilation but no use of respiratory protection were applied. Results: PROCs 4, 5, 8a, 10, and 15 were assigned to ten uses of methanol. The uses include as a solvent for manufacturing sun cream, surfactants, dyestuffs, films and adhesives. Methanol was also used as a component in a release agent, hardening media and mold wash for cast products as well as a component of hard-coating solution and a viscosity-controlling agent for manufacturing glass lenses. PROC 8a and PROC 10 of a cast product manufacturer without LEV (local exhaust ventilation) and general ventilation as well as no respiratory protection resulted in the highest exposure to methanol. Assuming the identical worst OCs and RMMs for all uses, exposures from PROC 5, 8a, and 10 were the same and the highest followed by PROC 4 and 15. The estimation resulted in higher exposures in nine uses except one use where measured exposure approximated exposures without RMMs. Conclusions: The role of ECETOC TRA as a conservative exposure assessment tool was confirmed by comparison with measured data. Moreover, it can guide which RMMs should be applied for the safe use of methanol.
참고문헌 (31)
- ECETOC TRA Version 3:Background and Rationale for the Improvements, "European Centre for Ecotoxicology and Toxicology of Chemicals", European Centre for Ecotoxicology and Toxicology of Chemicals, ~, pp.ECETOC Technical Report No. 114 (2012)
- European Centre for Ecotoxicology and Toxicology of Chemicals, "User Guide for the Integrated Tool TRAM Version 3.1", European Centre for Ecotoxicology and Toxicology of Chemicals, ~ (2017)
- Urbanus J, "The ECETOC-targeted risk assessment tool for worker exposure estimation in REACH registration dossiers of chemical substancescurrent developments", Int J Environ Res Public Health, 17(22), pp.8443~ (2020)
- Kupczewska-Dobecka M, "Evaluation of the TRA ECETOC model for inhalation workplace exposure to different organic solvents for selected process categories", Int J Occup Med Environ Health, 24(2), pp.208~217 (2011)
- 고원경, "작업환경측정과 노출평가 프로그램(ECETOC TRA) 비교에 따른 위해성 평가에 관한 연구", 대한안전경영과학회지, 15(3), pp.1~6 (2013), 대한안전경영과학회[DOI]
- 김기은, "공정 범주에 따른 ECETOC TRA 모델 평가로부터 도출한 한국 작업장 노출 평가 개선 방안", 한국환경보건학회지, 45(2), pp.173~185 (2019), 한국환경보건학회
- Spinazzè A, "Accuracy evaluation of three modelling tools for occupational exposure assessment", Ann Work Expo Health, 61(3), pp.284~298 (2017)
- Lee S, "Comparison of quantitative exposure models for occupational exposure to organic solvents in Korea", Ann Work Expo Health, 63(2), pp.197~217 (2019)
- Lee EG, "Evaluation of exposure assessment tools under REACH : Part I-tier 1tools", Ann Work Expo Health, 63(2), pp.218~229 (2019)
- Ishii S, "Evaluation of the ECETOC TRA model for workplace inhalation exposure to ethylbenzene in Japan", J Chem Health Saf, 24(1), pp.8~20 (2017)
- 문준식, "노출 모델의 화평법 적용성: ECETOC TRA와 Stoffenmanager Tier 1 노출 모델을 활용한 벤젠의 작업자 노출 평가", 한국환경보건학회지, 44(5), pp.460~467 (2018), 한국환경보건학회
- Spinazzè A, "How to obtain a reliable estimate of occupational exposure? Review and discussion of models' reliability", Int J Environ Res Public Health, 16(15), pp.2764~ (2019)
- Fransman W, "How accurate and reliable are exposure models?", Ann Work Expo Health, 61(8), pp.907~991 (2017)
- Guidance Document for the Preparation of Chemical Safety Report 2021 Ver.2, "National Institute of Environmental Research", National Institute of Environmental Research, ~, pp.NIER-GP2016-163 (2021)
- Study for the Evaluation Process of Chemical Safety Report Prepared under K-REACH (I), "Korea Institute of Industrial Technology", National Institute of Environmental Research, ~, pp.NIER-SP2018-164 (2019)
- "Act No. 3532. Occupational Safety and Health Act"[URL]
- Korea Occupational Safety and Health Agency, "KOSHA Guide A-117-2014. Technical Guideline to Methanol Exposure Measurements According to the Working Environment Monitoring System", Korea Occupational Safety and Health Agency, ~ (2014)
- "Targeted Risk Assessment"[URL]
- "Methanol Toxicological Summary"[URL]
- "Immediately Dangerous to Life or Health (IDLH) Values for Methyl Alcohol"[URL]
- Korea Occupational Safety and Health Agency, "KOSHA 2012-Instructional media-979. Guidance on Working Environment Monitoring System", Korea Occupational Safety and Health Agency, ~ (2012)
- Toray Advanced Materials Korea Inc, "Silicone release film and manufacturing method thereof", South Korea KR101522941B1. 2015 May 26, ~ (2015)
- Korea Occupational Safety and Health Agency, "Instruction Materials for Safety in a Casting and Forging Industry Sector", Korea Occupational Safety and Health Agency, ~ (2014)
- Korean Agency for Technology and Standards, "Standard Terms for a Metal Industry Sector", Korean Agency for Technology and Standards, ~ (2010)
- Gooch JW, "Encyclopedic Dictionary of Polymers", pp.697~ (2011), Springer
- "Parting Agents, Breakdown Agents, Adhesive Agents"[URL]
- 이환종, "3D프린팅 주형의 표면품질 향상을 위한 도형제 적용기술 연구", 한국생산제조학회지, 27(6), pp.485~491 (2018), 한국생산제조학회[DOI]
- Svidró JT, "The effect of different binder levels on the heat absorption capacity of moulding mixtures made by the phenolic urethane cold-box process", J Therm Anal Calorim, 130, pp.1769~1777 (2017)
- Lee JH, "A study on the hard coating of ophthalmic lens", Theories Appl Chem Eng, 12(1), pp.40~43 (2006)
- Kolon Industries, Inc, "Composition for hard coating and hard coating film including cured product of the same as the coating layer. South Korea KR101967146B1. 2019 Apr 9", ~ (2019)
- Addendum to ECETOC Targeted Risk Assessment Report No. 93, "European Centre for Ecotoxicology and Toxicology of Chemicals", European Centre for Ecotoxicology and Toxicology of Chemicals, 69~70, pp.ECETOC Technical Report No. 107 (2009)