고자장 3T MRI 장비에서 동물영상을 위한 솔레노이드 RF 코일 개발
Development of Solenoid RF Coil for Animal Imaging in 3T High Magnetic Field MRI
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목적 : 본 연구는 3 T MRI 장비에 적합한 동물영상용 솔레노이드 (solenoid) 코일을 개발하고 최적화한 후, 실제 동물모델에 대한 영상을 획득하는 것을 목표로 수행되었다. 대상 및 방법 : 솔레노이드 코일은 반경 4 cm, 길이 10 cm의 아크릴 구조물에 너비 2 cm, 두께 0.05 cm, 길이 10 cm의 구리테잎으로 3번 감긴 형태로 제작하였고, 구리테잎을 감을 때는 실린더 축과 수직이 되도록 감았으며 테잎간의 간격은 2 cm로 하였다. 축전지 (capacitor)는 2-100 pF사이의 용량을 이용하였고, 코일은 수신 전용으로서 디자인되었다. 결과 : 개발된 솔레노이드 코일의 신호대 잡음비 (Signal to Noise Ratio; SNR)는 CuSO4 수용액 팬텀(CuSO4; 0.7 g/L)에서 985, 쥐 (rat)를 이용한 동물실험에서 995이었고, Qfactor는 unload된 경우 203-206, load된 경우 84-89정도로 측정되었다. 솔레노이드 코일을 이용하여 획득한 영상은 상대적으로 해상도 (resolution)가 높았으며, 코일 시뮬레이션 (simulation)을 통해서 얻은 RF field의 균질성 (homogeneity) 또한 매우 우수하였다. 결론 : 본 연구를 통하여 고자장 3T MRI 장비에서 쥐와 같은 작은 동물의 영상을 획득할 때 솔레노이드 코일을 사용하면 보다 향상된 영상의 대조도, 해상도, 선명도를 얻을 수 있는 가능성을 확인 할 수 있었다.
Abstract
Purpose : The purpose of the present study was to develop and optimize solenoid coil for animal- model in 3 T MRI system and investigate and compare with the birdcage coil concerning the image quality with the various parameters such as SNR and Q-factor. Materials and Methods : Solenoid coil for animal-model was made on the acryl structure (diameter 4 cm, length 10 cm) 3 times-winding cooper tape of width 2 cm , thickness 0.05 cm and length 10 cm with 2 cm interval between winded tapes. Capacitors from 2 pF to 100 pF were used, and the solenoid coil was designed for receiver only coil. Results : SNR of the developed solenoid was 985 in CuSO4 0.7 g/L and 995 in rat experiment. Q-factor was 84-89 in unloaded condition and 203-206 in loaded condition. Conclusion : The resolution of the image obtained from solenoid was relatively higher than that of the conventional birdcage coil. In addition, the homogeneity of RF field by coil simulation was significantly excellent. The present study demonstrated that the solenoid coil could be useful to obtain small animal images with better contrast, resolution, visibility than images from birdcage.
참고문헌 (23)
- Susann B, "High-field diffusiontensor imaging of mouse brain in vivo using single-shotSTEAM MRI", 30, pp.112~117 (2007)
- Routley NR, "The HALO system--a light weightportable imaging system", 22, pp.1145~1151 (2004)
- Busse H, "Advanced approach for intraoperative MRI guid-ance and potential benefit for neurosurgical applications", 24, pp.140~151 (2006)
- "High resolution black-blood MRI of the carotid vessel wall using phased-array coils at 1.5 and 3 Tesla", 12(12), pp.1521~1526 (2005)
- "Low-frequency quadrature mode birdcage resonator", 5, pp.33~37 (1997)
- "The develop-ment and optimization of high spatial resolution MRI for imag-ing the oesophagus using an external surface coil", 79, pp.873~879 (2006)
- "Inductively coupled RF coilsfor examinations of small animals and objects in standard w-hole-body MR scanners", 30(6), pp.1241~1245 (2003)
- "An inverse method to designRF coil arrays optimized for SENSE imaging", 51, pp.6457~6469 (2006)
- "Manganese-enhanced 3D MRI of established anddisrupted synaptic activity in the developing insect brain in vi-vo", 158, pp.50~55 (2006)
- "A sole-noid-like coil producing transverse RF fields for MR imaging", 127, pp.73~79 (1997)
- "3T MR Imaging The Pros and Cons", 25, pp.1455~1456 (2004)
- "Evaluation of the RF field uniformityof a double-tuned 31P", 1H birdcage RF coil for spin-echo M-RI, pp.2005, 22[DOI]
- "Intravenous infusion ofimmortalized human mesenchymal stem cells protects againstinjury in a cerebral ischemia model in adult rat", 199(1), pp.55~56 (2006)
- "B0homogeneity throughout the monkey brain is strongly im-proved in the sphinx position as compared to the supine posi-tion", 23, pp.408~412 (2006)
- "Electromagnetic analysis and design in magneticresonance imaging. 1st ed", pp.140~141 (1999), Illinois: CRC press,
- "Does high-field MRimaging have an influence on the classification of patients withclinically isolated syndromes according to current diagnosticMR imaging criteria for multiple sclerosis?", 27, pp.1794~1798 (2005)
- "An efficient designfor birdcage probes, dedicated to small-animal imaging experi-ments", 17, pp.363~371 (2004)
- "Practical design of a 4 Tesla double-tuned RF surfacecoil for interleaved 1H and 23Na MRI of rat brain", 181, pp.203~211 (2006)
- "High-resolutionblack-blood MRI of the carotid vessel wall using phased-arraycoils at 1.5 and 3 Tesla", 12, pp.1521~1526 (2005)
- "Micro-strip RF surface coil de-sign for extremely high-field MRI and spectroscopy", 46, pp.443~450 (2001)
- "Development of an agar phantom adaptablefor simulation of various tissues in the range", pp.221~226
- "Anatomic relation-ship of the oculomotor nuclear medial longitudinal fasciculusin the midbrain", 18, pp.111~113 (1997)
- "Solenoidal microcoil design_Part IIOptimizing winding parameters for maximum signal-to-noiseperformance", 133, pp.190~210 (2001)