Lactobacillus spp. 의 항산화 효과 및 활성산소에 대한 내성
Antioxidant activity and Tolerance to reactive oxygen species of Lactobacillus spp.
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초록
본 연구에서는 4종류의 Lactobacillus spp.의 항산화 효과와 활성산소에 대한 내성을 측정하였다. 그 결과 L. casei KCTC 3260의 항산화 효과가 intact cell에서 36.9%, cell lysate에서 79.8%로서 높은 항산화 효과를 나타내었다. 또한 1mM 농도의 hydrogen peroxide에서 생존성에 직접적으로 영향을 받지 않는 등 활성산소에 대해서 높은 내성을 나타내었다. 또한 높은 GPX 활성이 활성산소 하에서 L. casei KCTC 3260의 생존성에 중요한 역할을 하는 것으로 생각된다.
Abstract
The four Lactobacillus spp. were investigated for their antioxidant properties, including antioxidant activity, tolerance to reactive oxygen species, hydroxy radical scavenging activity and ferrous iron chelating activity. Also, activities of superoxide dismutase and glutathione peroxidase were investigated. From the results of this work, the intact cell and cell lysate of L. casei KCTC 3260 were exhibited highest antioxidant activity. L. casei KCTC 3260 also showed strong tolerance to reactive oxygen species. This strain showed highest glutathione peroxidase activity among the tested strains.
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