Effects of pH and Light Irradiation on Coenzyme Q10 Production Using Rhodobacter sphaeroides
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To increase the level of CoQ10 production in mass culture, the effects of pH and light irradiation on CoQ10 production by Rhodobacter sphaeroides were investigated in a 1-L bioreactor. CoQ10 production was growth-associated, and the highest production of CoQ10 (1.69 mg/g dry cell) was obtained under uncontrolled pH; this production was 1.7 times higher than that obtained at controlled pH 7. Therefore, pH was a key factor affecting CoQ10 production. The effect of light irradiation on CoQ10 production was negligible. This result offers an advantage for mass production of CoQ10.
Abstract
To increase the level of CoQ10 production in mass culture, the effects of pH and light irradiation on CoQ10 production by Rhodobacter sphaeroides were investigated in a 1-L bioreactor. CoQ10 production was growth-associated, and the highest production of CoQ10 (1.69 mg/g dry cell) was obtained under uncontrolled pH; this production was 1.7 times higher than that obtained at controlled pH 7. Therefore, pH was a key factor affecting CoQ10 production. The effect of light irradiation on CoQ10 production was negligible. This result offers an advantage for mass production of CoQ10.
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