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蔘蘇飮의 항알레르기 效果

Anti-allergic Effects of Shensuyin

이시형|신조영|이승언
대한한방내과학회 (The Society Of Korean Oriental Internal Medicine)|2005.03|대한한방내과학회지 (The Journal of Korean Oriental Internal Medicine)|제26권 제1호|pp. 1-15

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Abstract

Objective : Mast cells, a central component of all allergic disease, are distributed in the skin and the mucosa of gastrointestinal or respiratory tracts and there happen immediate hypersensitivity reaction resulting inflammatory process. Shensuyin(SSE) has been used for the treatment of headache, coughs and much phlegm, especially allergic rhinitis (hay fever) as a traditional medicine in Korea. Methods : The author examined the effects of Shensuyin (SSY) on mast cell-mediated anaphylactic-like reactions in a murine model. Results : SSY dose-dependently inhibited compound 48/80-induced systemic anaphylactic-like shock reaction and ear swelling response. When SSY was given as pre-treatment at concentrations ranging from 0.01 to 1 ㎎/㎖, the histamine release from rat peritoneal mast cells induced by compound 48/80. Mast cells can be activated through different receptors via cross-linkage of the high-affinity IgE receptor. SSY also inhibited passive cutaneous anaphylaxis by oral administration in a dose-dependent manner. Conclusion : These data provide that SSY may possess a strong anti-anaphylactic activity.

참고문헌 (28)

  1. "Anti-allergic effects of Samsoeum and Samsoeumgamibang", pp.2002~, Kyunghee univesity
  2. "Molecular aspects of allergy", 23, pp.413~62 (2002)
  3. "Allergen-induced histamine release in intact human skin in vivo assessed by skin microdialysis technique:characterization of factors influencing histamine releasability", 97, pp.672~9 (1996)
  4. "Inhibition of immediate type allergic reactions by the aqueous extract of Kum-Hwang-San International Journal of Immunophamacology", 20, pp.285~94 (1998)
  5. "Extracelluar ATP activates mast cells via a mechanism that is different from the activation induced by the cross-linking of Fe receptor", 156, pp.3970~9 (1996)
  6. "Effect of Kumhwang-san on anaphylactic reaction in a murine model", 21, pp.163~74 (1999)
  7. "Role of TGF-beta1 on the IgE-dependent anaphylaxis reaction", 162, pp.4960~5 (1999)
  8. "The receptor with high affinity for immunoglobulin E", 4, pp.419~70 (1986)
  9. "Structure-function relationships in the mast cell high affinity receptor for IgE Role of the cytoplasmic domains and of the beta subunit Journal of Biological Chemistry", pp.22613~20 (1991)
  10. "Tongkyutang inhibits mast cell-dependent allergic reactions and inflammatory cytokine secretion", 319, pp.35~41 (2002)
  11. "Supernormal histamine release and normal cytotoxic activity of beige rat mast cells with giant granules International Archives of Allergy and Immunology", pp.99~106 (1993)
  12. "Native heparin from rat peritoneal mast cells", 252, pp.518~21 (1977)
  13. "A method for fluorometric assay of histamine in tissues", 127, pp.182~6 (1959)
  14. "A new method for extraction of extravasated dye in the skin and the influence of fasting stress on passive cutaneous allergy in guinea pigs and rats", 22, pp.89~101 (1978)
  15. "Lavender oil inhibits immediate-type allergic reaction in mice and rats", 51, pp.221~6 (1999)
  16. "125I-fibrin deposition in IgE dependent immediate-type hypersensitivity reactions reaction in mouse skin:demonstration of the role of mast cells using genetically mast cell-deficient mice locally reconstituted with cultured mast cells", 139, pp.2605~14 (1987)
  17. "Direct activation of GTP-binding regulatory proteins", pp.260~2 (1990)
  18. "Interaction of substance P compound 48", 80 and mastoparan with α-subunit C-terminal of G protein, 1990, 355~8
  19. "Effect of Phlomis umbrosa root on mast cell-dependent immediate-type allergic reactions by anal therapy", 25, pp.73~85 (2003)
  20. "Compound 48", 80 activates mast cell phospholipase D via heterotrimeric GTP-binding proteins, 2000, pp.292, 122~30
  21. "Functional compartments in rat mast cells for cAMP and calcium on histamine release", 12, pp.343~50 (2000)
  22. "Intracellular calcium release induced by histamine releasers and its inhibition by some antiallergic drugs", 56, pp.464~9 (1986)
  23. "Mast cell recovery following chronic treatment with compound 48", 80, 1994, pp.105, 274~80
  24. "Inhibition of mast cell-dependent anaphylactic reactions by the pigment of polygonum tinctorium(Chung-Dae)in rats", 31(3), pp.361~5 (1998)
  25. "Suppression of immunoglobulin E-mediated anaphylactic reactions by Hwanglyun - Haedok-Tang water extracts", 61(2), pp.127~34 (1998)
  26. "Effects of Poncirus trifoliata on type Ⅰ hypersensitivity reaction", 25(1), pp.51~6 (1997)
  27. "Suppression of immunoglobulin E-mediated anaphylactic reactions by Alpinia oxyphylla in rats", 22(2), pp.267~77 (2000)
  28. "Effect of Korean folk medicine Chung-Dae-San on mast cell-dependent anaphylactic reaction", 64(1), pp.45~52 (1999)

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