Effect of palmitoleic acid on the differentiation of bovine skeletal muscle satellite cells
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We hypothesized that the unsaturated fatty acid palmitoleic acid (POA) could promote the expression of adipogenic/lipogenic genes in bovine skeletal muscle satellite cells (BSCs). The BSCs were cultured in a growth medium containing 10% fetal bovine serum. When the cells reached 80%–90% confluence, we used the differentiation medium with 5% horse serum for differentiation for 96 h. The differentiation medium contained 50 μM, 100 μM and 200 μM POA. Control BSC were cultured only in differentiation media. Compared with the control BSC, the POA BSC significantly up-regulated the expression of paired box 3 (Pax3) and paired box 7 (Pax7) and down-regulated myogenin gene expression (p < 0.01), which indicates a depression in muscle fiber development. However, all POA treatments up-regulated the expression of the adipocyte transcription factors peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer-binding protein alpha and beta (C/EBP α and C/EBP β), and other genes (p < 0.01) and increased the expression of PAT-family proteins and the concentration of adiponectin in the media. These results indicate that POA can convert part of BSCs into adipocytes.
Abstract
We hypothesized that the unsaturated fatty acid palmitoleic acid (POA) could promote the expression of adipogenic/lipogenic genes in bovine skeletal muscle satellite cells (BSCs). The BSCs were cultured in a growth medium containing 10% fetal bovine serum. When the cells reached 80%–90% confluence, we used the differentiation medium with 5% horse serum for differentiation for 96 h. The differentiation medium contained 50 μM, 100 μM and 200 μM POA. Control BSC were cultured only in differentiation media. Compared with the control BSC, the POA BSC significantly up-regulated the expression of paired box 3 (Pax3) and paired box 7 (Pax7) and down-regulated myogenin gene expression (p < 0.01), which indicates a depression in muscle fiber development. However, all POA treatments up-regulated the expression of the adipocyte transcription factors peroxisome proliferator-activated receptor γ (PPARγ), CCAAT/enhancer-binding protein alpha and beta (C/EBP α and C/EBP β), and other genes (p < 0.01) and increased the expression of PAT-family proteins and the concentration of adiponectin in the media. These results indicate that POA can convert part of BSCs into adipocytes.
참고문헌 (50)
- M.M. Ladeira, "Review: Nutrigenomics of marbling and fatty acid profile in ruminant meat", Animal, 12, pp.s282~s294 (2018), Elsevier BV[DOI]
- Baik M, "Triennial Growth and Development Symposium: molecular mechanisms related to bovine intramuscular fat deposition in the longissimus muscle", J Anim Sci, 95, pp.2284~2303 (2017)
- Chen J, "The fractal dimension research of chinese and american beef marbling standards images", Proceedings of the International Conference on Computer & Computing Technologies in Agriculture (2012)
- J.F. Hocquette, "Intramuscular fat content in meat-producing animals: development, genetic and nutritional control, and identification of putative markers", Animal, 4(2), pp.303~319 (2010), Elsevier BV[DOI]
- N. Mach, "Burdizzo pre-pubertal castration effects on performance, behaviour, carcass characteristics, and meat quality of Holstein bulls fed high-concentrate diets", Meat Science, 81(2), pp.329~334 (2009), Elsevier BV[DOI]
- M.A. Brooks, "CASE STUDY:Carcass and meat characteristics and M. longissimus thoracis histology of beef from calf-fed and yearling-fed Angus steers", The Professional Animal Scientist, 27(4), pp.385~393 (2011), American Registry of Professional Animal Scientists[DOI]
- W. G. MOODY, "A Quantitative and Morphological Study of Bovine Longissimus Fat Cells", Journal of Food Science, 33(1), pp.47~52 (1968), Wiley[DOI]
- Smith SB, "Marbling: management of cattle to maximize the deposition of intramuscular adipose tissue", Proceedings of the Plains Nutrition Council Spring Conference (2007)
- A. J. Garmyn, "Estimation of relationships between mineral concentration and fatty acid composition of longissimus muscle and beef palatability traits", Journal of Animal Science, 89(9), pp.2849~2858 (2011), Oxford University Press (OUP)[DOI]
- Charlotte A. Collins, "Stem Cell Function, Self-Renewal, and Behavioral Heterogeneity of Cells from the Adult Muscle Satellite Cell Niche", Cell, 122(2), pp.289~301 (2005), Elsevier BV[DOI]
- Gabi Shefer, "Skeletal muscle satellite cells can spontaneously enter an alternative mesenchymal pathway", Journal of Cell Science, 117(22), pp.5393~5404 (2004), The Company of Biologists[DOI]
- Marie Csete, "Oxygen-mediated regulation of skeletal muscle satellite cell proliferation and adipogenesis in culture", Journal of Cellular Physiology, 189(2), pp.189~196 (2001), Wiley[DOI]
- Lydia Teboul, "Thiazolidinediones and Fatty Acids Convert Myogenic Cells into Adipose-like Cells", Journal of Biological Chemistry, 270(47), pp.28183~28187 (1995), Elsevier BV[DOI]
- Xiang Z Li, "Oleic acid in the absence of a PPARγ agonist increases adipogenic gene expression in bovine muscle satellite cells1", Journal of Animal Science, 97(10), pp.4114~4123 (2019), Oxford University Press (OUP)[DOI]
- David L. Satory, "Conjugated Linoleic Acid Inhibits Proliferation but Stimulates Lipid Filling of Murine 3T3-L1 Preadipocytes", The Journal of Nutrition, 129(1), pp.92~97 (1999), Oxford University Press (OUP)[DOI]
- Manuel J. Deutsch, "Digital image analysis approach for lipid droplet size quantitation of Oil Red O-stained cultured cells", Analytical Biochemistry, 445, pp.87~89 (2014), Elsevier BV[DOI]
- Sung-Ho Kook, "Satellite Cells Isolated from Adult Hanwoo Muscle Can Proliferate and Differentiate into Myoblasts and Adipose-like Cells", Molecules and Cells, 22(2), pp.239~245 (2006), 한국분자세포생물학회
- Jiahui Xu, "Fatty acids promote bovine skeletal muscle satellite cell differentiation by regulating ELOVL3 expression", Cell and Tissue Research, 373(2), pp.499~508 (2018), Springer Science and Business Media LLC[DOI]
- I Cassar-Malek, "Regulation of bovine satellite cell proliferation and differentiation by insulin and triiodothyronine", Domestic Animal Endocrinology, 17(4), pp.373~388 (1999), Elsevier BV[DOI]
- Patrick Seale, "A new look at the origin, function, and “stem-cell” status of muscle satellite cells", Developmental Biology, 218(2), pp.115~124 (2000), Elsevier BV[DOI]
- Rowland H. Han, "Simulation of triacylglycerol ion profiles: bioinformatics for interpretation of triacylglycerol biosynthesis", Journal of Lipid Research, 54(4), pp.1023~1032 (2013), Elsevier BV[DOI]
- Seong H. Choi, "Co-culture of bovine muscle satellite cells with preadipocytes increases PPARγ and C", EBPβ gene expression in differentiated myoblasts and increases GPR43 gene expression in adipocytes, 2013, pp.24(3), 539~543[DOI]
- S. H. Choi, "AMPKα, C", EBPβ, CPT1β, GPR43, PPARγ, and SCD Gene Expression in Single- and Co-cultured Bovine Satellite Cells and Intramuscular Preadipocytes Treated with Palmitic, Stearic, Oleic, and Linoleic Acid, 2015, pp.28(3), 411~419[DOI]
- Peter Tontonoz, "Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor γ", Current Opinion in Genetics & Development, 5(5), pp.571~576 (1995), Elsevier BV[DOI]
- Anthony N. Hollenberg, "Functional Antagonism between CCAAT", Enhancer Binding Protein-α and Peroxisome Proliferator-activated Receptor-γ on the Leptin Promoter, 1997, pp.272(8), 5283~5290[DOI]
- A. K. G. Kadegowda, "Inhibition of Stearoyl-CoA Desaturase 1 Reduces Lipogenesis in Primary Bovine Adipocytes", Lipids, 48(10), pp.967~976 (2013), Wiley[DOI]
- Eunha Kim, "Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro", European Journal of Pharmacology, 672(1-3), pp.38~44 (2011), Elsevier BV[DOI]
- D. Grahame Hardie, "The AMP-Activated Protein Kinase. Fuel Gauge of the Mammalian Cell?", European Journal of Biochemistry, 246(2), pp.259~273 (1997), Wiley[DOI]
- Silvia Bijland, "Role of AMP-activated protein kinase in adipose tissue metabolism and inflammation", Clinical Science, 124(8), pp.491~507 (2013), Portland Press Ltd.[DOI]
- Sonia Fernández-Veledo, "Role of energy- and nutrient-sensing kinases AMP-activated protein kinase (AMPK)and mammalian target of rapamycin (mTOR) in adipocyte differentiation", IUBMB Life, 65(7), pp.572~583 (2013), Wiley[DOI]
- H. Zong, "AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation", Proceedings of the National Academy of Sciences, 99(25), pp.15983~15987 (2002), Proceedings of the National Academy of Sciences[DOI]
- Arend Bonen, "Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT", CD36, 2004, pp.18(10), 1144~1146[DOI]
- David E. Kelley, "Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss", American Journal of Physiology-Endocrinology and Metabolism, 277(6), pp.E1130~E1141 (1999), American Physiological Society[DOI]
- D. E. Kelley, "Effects of insulin on skeletal muscle glucose storage, oxidation, and glycolysis in humans", American Journal of Physiology-Endocrinology and Metabolism, 258(6), pp.E923~E929 (1990), American Physiological Society[DOI]
- Jean‐Aimé Simoneau, "Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss", The FASEB Journal, 13(14), pp.2051~2060 (1999), Wiley[DOI]
- K. Y. Chung, "Melengestrol acetate enhances adipogenic gene expression in cultured muscle-derived cells", Journal of Animal Science, 87(12), pp.3897~3904 (2009), Oxford University Press (OUP)[DOI]
- Abdou Rachid Thiam, "The biophysics and cell biology of lipid droplets", Nature Reviews Molecular Cell Biology, 14(12), pp.775~786 (2013), Springer Science and Business Media LLC[DOI]
- Perry E. Bickel, "PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores", Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1791(6), pp.419~440 (2009), Elsevier BV[DOI]
- A.S. Greenberg, "Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets", Journal of Biological Chemistry, 266(17), pp.11341~11346 (1991), Elsevier BV[DOI]
- Nathan E. Wolins, "A proposed model of fat packaging by exchangeable lipid droplet proteins", FEBS Letters, 580(23), pp.5484~5491 (2006), Wiley[DOI]
- H. W. Heid, "Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases", Cell and Tissue Research, 294(2), pp.309~321 (1998), Springer Science and Business Media LLC[DOI]
- D L Brasaemle, "Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein", Journal of Lipid Research, 38(11), pp.2249~2263 (1997), Elsevier BV[DOI]
- Minako Imamura, "ADRP stimulates lipid accumulation and lipid droplet formation in murine fibroblasts", American Journal of Physiology-Endocrinology and Metabolism, 283(4), pp.E775~E783 (2002), American Physiological Society[DOI]
- Peter J. Havel, "Update on adipocyte hormones: regulation of energy balance and carbohydrate", lipid metabolism, 2004, pp.53(suppl_1), S143~S151[DOI]
- P. Trayhurn, "Endocrine and signalling role of adipose tissue: new perspectives on fat", Acta Physiologica Scandinavica, 184(4), pp.285~293 (2005), Wiley[DOI]
- Anders H. Berg, "The adipocyte-secreted protein Acrp30 enhances hepatic insulin action", Nature Medicine, 7(8), pp.947~953 (2001), Springer Science and Business Media LLC[DOI]
- Noriyuki Ouchi, "Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin", Circulation, 100(25), pp.2473~2476 (1999), Ovid Technologies (Wolters Kluwer Health)[DOI]
- T. Yamauchi, "The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity", Nature Medicine, 7(8), pp.941~946 (2001), Springer Science and Business Media LLC[DOI]
- Valerie Christiaens, "CD36 promotes adipocyte differentiation and adipogenesis", Biochimica et Biophysica Acta (BBA) - General Subjects, 1820(7), pp.949~956 (2012), Elsevier BV[DOI]
- Joost J.F.P. Luiken, "Post-translational modifications of CD36 (SR-B2): Implications for regulation of myocellular fatty acid uptake", Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1862(12), pp.2253~2258 (2016), Elsevier BV[DOI]
