명상 임상시험의 국제적 동향 분석 : WHO ICTRP 레지스트리를 중심으로
Global Trends in Meditation Clinical Trials Based on WHO ICTRP
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Objectives : Meditation-based interventions are increasingly recognized as evidence-informed approaches in clinical medicine. However, a comprehensive global analysis of meditation-related clinical trials remains scarce. This study presents the first systematic characterization of meditation trials registered in the World Health Organization International Clinical Trials Registry Platform(WHO ICTRP), aiming to map global trends, cultural and methodological patterns, delivery formats, and international collaboration structures. Methods : A systematic search was conducted via the WHO ICTRP Advanced Search interface on July 6, 2025. After a screening process, trials were analyzed for temporal trends, health conditions, meditation types, program durations, delivery methods, primary outcomes and collaboration networks. Results : From 354 initial trials, 291 meditation-related clinical trials from 27 countries (2006-2025) were analyzed. Annual registrations showed accelerated growth after 2017, peaking at 59 trials in 2024. Mindfulness-based interventions dominated (50.52%), followed by yoga-based approaches (26.12%). Healthy individuals were the most studied population(28.52%), with cancer(9.97%), gynecological conditions (8.59%), and neurological disorders(7.90%) being the most frequent disease categories. Among trials with specified delivery methods, face-to-face delivery was most common(43.05%), though online/virtual approaches showed increasing trends over time. Medium-term programs(5-12 weeks) were most prevalent(57.54%). Cross-sectional analysis of primary outcomes revealed that mental health indicators were predominantly used in healthy populations, while disease-specific measures were prioritized in corresponding patient groups. International collaboration revealed two distinct ecosystems with a US-centered Western network contrasting with independent research traditions in India, China, and Iran. Conclusion : Meditation clinical trials demonstrate rapid growth and expanding therapeutic applications beyond mental health into preventive health promotion and diverse medical conditions. The field shows dual characteristics of evidence-based medical integration and cultural diversity in research approaches. These findings provide essential baseline data for future meditation research prioritization and clinical policy development.
Abstract
Objectives : Meditation-based interventions are increasingly recognized as evidence-informed approaches in clinical medicine. However, a comprehensive global analysis of meditation-related clinical trials remains scarce. This study presents the first systematic characterization of meditation trials registered in the World Health Organization International Clinical Trials Registry Platform(WHO ICTRP), aiming to map global trends, cultural and methodological patterns, delivery formats, and international collaboration structures. Methods : A systematic search was conducted via the WHO ICTRP Advanced Search interface on July 6, 2025. After a screening process, trials were analyzed for temporal trends, health conditions, meditation types, program durations, delivery methods, primary outcomes and collaboration networks. Results : From 354 initial trials, 291 meditation-related clinical trials from 27 countries (2006-2025) were analyzed. Annual registrations showed accelerated growth after 2017, peaking at 59 trials in 2024. Mindfulness-based interventions dominated (50.52%), followed by yoga-based approaches (26.12%). Healthy individuals were the most studied population(28.52%), with cancer(9.97%), gynecological conditions (8.59%), and neurological disorders(7.90%) being the most frequent disease categories. Among trials with specified delivery methods, face-to-face delivery was most common(43.05%), though online/virtual approaches showed increasing trends over time. Medium-term programs(5-12 weeks) were most prevalent(57.54%). Cross-sectional analysis of primary outcomes revealed that mental health indicators were predominantly used in healthy populations, while disease-specific measures were prioritized in corresponding patient groups. International collaboration revealed two distinct ecosystems with a US-centered Western network contrasting with independent research traditions in India, China, and Iran. Conclusion : Meditation clinical trials demonstrate rapid growth and expanding therapeutic applications beyond mental health into preventive health promotion and diverse medical conditions. The field shows dual characteristics of evidence-based medical integration and cultural diversity in research approaches. These findings provide essential baseline data for future meditation research prioritization and clinical policy development.