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사료 내 Silymarin의 첨가가 흰다리새우(Litopenaeus vannamei)의 성장, 사료효율, 비특이적 면역력 및 항산화력에 미치는 영향

Effects of Dietary Silymarin on Growth Performance, Feed Utilization, Innate Immunity and Antioxidant Capacity of Pacific White Shrimp Litopenaeus vannamei

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초록

This study was conducted to evaluate the effects of dietary silymarin supplementation on the growth performance, feed utilization, innate immunity and antioxidant capacity of Pacific white shrimp Litopenaeus vannamei. Four experimental diets were formulated to contain 0, 0.025, 0.05 and 0.1% silymarin (designated as Con, S0025, S005 and S01, respectively). Triplicate groups of shrimp (initial body weight: 0.70 g) were fed each of the diets for 6 weeks. After the feeding trial, weight gain and specific growth rate were significantly higher in silymarin-supplemented groups compared to Con group. Dietary silymarin significantly enhanced protein efficiency ratio of S01 group and reduced feed conversion ratio of S005 and S01 groups. Phenoloxidase and anti-protease activities were significantly higher in S01 group compared to Con group. Glutathione peroxidase and catalase activities were significantly higher in silymarin-supplemented groups compared to those of Con group. The results of this study indicate that dietary silymarin could improve the growth performance, feed utilization, innate immunity and antioxidant capacity of Pacific white shrimp. The optimum level of silymarin in diet for Pacific white shrimp is suggested to be ≥0.025%.

Abstract

This study was conducted to evaluate the effects of dietary silymarin supplementation on the growth performance, feed utilization, innate immunity and antioxidant capacity of Pacific white shrimp Litopenaeus vannamei. Four experimental diets were formulated to contain 0, 0.025, 0.05 and 0.1% silymarin (designated as Con, S0025, S005 and S01, respectively). Triplicate groups of shrimp (initial body weight: 0.70 g) were fed each of the diets for 6 weeks. After the feeding trial, weight gain and specific growth rate were significantly higher in silymarin-supplemented groups compared to Con group. Dietary silymarin significantly enhanced protein efficiency ratio of S01 group and reduced feed conversion ratio of S005 and S01 groups. Phenoloxidase and anti-protease activities were significantly higher in S01 group compared to Con group. Glutathione peroxidase and catalase activities were significantly higher in silymarin-supplemented groups compared to those of Con group. The results of this study indicate that dietary silymarin could improve the growth performance, feed utilization, innate immunity and antioxidant capacity of Pacific white shrimp. The optimum level of silymarin in diet for Pacific white shrimp is suggested to be ≥0.025%.

참고문헌 (44)

  1. Abdel-Latif HM, "Milk thistle (Silybum marianum) extract improves growth, immunity, serum biochemical indices, antioxidant state, hepatic histoarchitecture, and intestinal histomorphometry of striped catfish, Pangasianodon hypophthalmus", Aquaculture, 562, pp.738761~ (2023)[DOI]
  2. Abenavoli L, "Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases", Phytother Res, 32, pp.2202~2213 (2018)[DOI]
  3. Ahmadi K, "Evaluation of the immunomodulatory effects of silymarin extract (Silybum marianum) on some immune parameters of rainbow trout, Oncorhynchus mykiss (Actinopterygii: Salmoniformes: Salmonidae)", Acta Ichthyol Piscat, 42, pp.113~120 (2012)[DOI]
  4. Official Methods of Analysis, "AOAC", Association of Official Analytical Chemists, ~ (2005)
  5. Arts IC, "Polyphenols and disease risk in epidemiologic studies", Am J Clin Nutr, 81, pp.317S~325S (2005)[DOI]
  6. Banaee M, "Effects of long-term silymarin oral supplementation on the blood biochemical profile of rainbow trout (Oncorhynchus mykiss)", Fish Physiol Biochem, 37, pp.885~896 (2011)[DOI]
  7. Chakraborty SB, "Application of phytochemicals as immunostimulant, antipathogenic and antistress agents in finfish culture", Rev Aquac, 3, pp.103~119 (2011)[DOI]
  8. Chandran MN, "Influence of polyherbal formulation (AquaImmu) as a potential growth promotor and immunomodulator in shrimp Penaeus monodon", Aquac Rep, 4, pp.143~149 (2016)[DOI]
  9. Chou CH, "Effect of silymarin on lipid and alcohol metabolism in mice following long-term alcohol consumption", J Food Biochem, 36, pp.369~377 (2012)[DOI]
  10. Citarasu T, "Herbal biomedicines: A new opportunity for aquaculture industry", Aquac Int, 18, pp.403~414 (2010)[DOI]
  11. Dwivedi PS, "System biology-based investigation of Silymarin to trace hepatoprotective effect", Comput Biol Med, 142, pp.105223~ (2022)[DOI]
  12. El-Desouky TA, "Effect of ozone gas on degradation of aflatoxin B1 and Aspergillus flavus fungal", J Environ Anal Toxicol, 2, pp.128~ (2012)[DOI]
  13. El-Garhy HA, "Silybin content and overexpression of chalcone synthase genes in Silybum marianum L. plants under abiotic elicitation", Plant Physiol Biochem, 108, pp.191~202 (2016)[DOI]
  14. Ellis AE, "Tech Fish Immunol", pp.95~99 (1990), SOS Publication
  15. "Statics for Fisheries and Aquaculture in the World" (2020)[URL]
  16. Folch J, "A simple method for the isolation and purification of total lipids from animal tissues", J Biol Chem, 226, pp.497~509 (1957)[DOI]
  17. Galindo C, "Physiological and biochemical variations during the molt cycle in juvenile Litopenaeus vannamei under laboratory conditions", J Crustac Biol, 29, pp.544~549 (2009)[DOI]
  18. Hassaan MS, "Effect of Silybum marianum seeds as a feed additive on growth performance, serum biochemical indices, antioxidant status, and gene expression of Nile tilapia, Oreochromis niloticus (L.) fingerlings", Aquaculture, 509, pp.178~187 (2019)[DOI]
  19. Hernández-López J, "Activation of the prophenoloxidase system of the brown shrimp Penaeus californiensis Holmes", Comp Biochem Physiol Part C Pharmacol Toxicol Endocrinol, 113, pp.61~66 (1996)[DOI]
  20. Inyang IR, "Effects of sublethal concentrations of diazinon on total protein and transaminase activities in Clarias gariepinus", Curr Res J Biol Sci, 2, pp.390~395 (2010)
  21. Jia R, "The protective effect of silymarin on the carbon tetrachloride (CCl4)-induced liver injury in common carp (Cyprinus carpio)", Vitro Cell Dev Biol Animal, 49, pp.155~161 (2013)[DOI]
  22. Khazaei R, "A review on the mechanisms of the effect of silymarin in milk thistle (Silybum marianum) on some laboratory animals", Vet Med Sci, 8, pp.289~301 (2022)[DOI]
  23. "Survey on the Status of Aquaculture" (2021)[URL]
  24. Lawhavinit OA, "Effects of ethanol tumeric (Curcuma longa Linn.) extract against shrimp pathogenic Vibrio spp. and on growth performance and immune status of white shrimp (Litopenaeus vannamei)", Kasetsart J Nat Sci, 45, pp.70~77 (2011)
  25. Li M, "Medicinal herbs and phytochemicals to combat pathogens in aquaculture", Aquac Int, 30, pp.1239~1259 (2022)[DOI]
  26. Luo R, "Induction of immunity substance in Penaeus chinensis by Chinese herbal medicine", Oceanol Limnol Sinica, 28, pp.577~585 (1997)
  27. Mercier L, "Metabolic and immune responses in Pacific whiteleg shrimp Litopenaeus vannamei exposed to a repeated handling stress", Aquaculture, 258, pp.633~640 (2006)[DOI]
  28. Muthukumar K, "Glutathione peroxidase3 of Saccharomyces cerevisiae protects phospholipids during cadmium-induced oxidative stress", Antonie Van Leeuwenhoek, 99, pp.761~771 (2011)[DOI]
  29. Nordberg J, "Reactive oxygen species, antioxidants, and the mammalian thioredoxin system", Free Radical Biol Med, 31, pp.1287~1312 (2001)[DOI]
  30. Olusola SE, "The potentials of medicinal plant extracts as bio-antimicrobials in aquaculture", Int J Med Aromat Plants, 3, pp.404~412 (2013)
  31. Paglia DE, "Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase", J Lab Clin Med, 70, pp.158~169 (1967)[DOI]
  32. Sanchez R, "Fish nutrition additives in SHK-1 cells: Protective effects of silymarin", Adv Biosci Biotechnol, 7, pp.55~62 (2016)[DOI]
  33. Schümann J, "Silibinin protects mice from T cell-dependent liver injury☆", J Hepatol, 39, pp.333~340 (2003)[DOI]
  34. Sivaram V, "Growth and immune response of juvenile greasy groupers (Epinephelus tauvina) fed with herbal antibacterial active principle supplemented diets against Vibrio harveyi infections", Aquaculture, 237, pp.9~20 (2004)[DOI]
  35. Tassanakajon A, "Discovery of immune molecules and their crucial functions in shrimp immunity", Fish Shellfish Immunol, 34, pp.954~967 (2013)[DOI]
  36. Vargas-Mendoza N, "Hepatoprotective effect of silymarin", World J Hepatol, 6, pp.144~149 (2014)[DOI]
  37. Verdouw H, "Ammonia determination based on indophenol formation with sodium salicylate", Water Res, 12, pp.399~402 (1978)[DOI]
  38. Wang J, "Effects of silymarin on growth performance, antioxidant capacity and immune response in turbot (Scophthalmus maximus L.)", J World Aquac Soc, 50, pp.1168~1181 (2019)[DOI]
  39. Wei L, "Dietary silymarin supplementation enhanced growth performance and improved intestinal apical junctional complex on juvenile grass carp (Ctenopharyngodon idella)", Aquaculture, 525, pp.735311~ (2020)[DOI]
  40. Wu JP, "Silymarin accelerates liver regeneration after partial hepatectomy", Evid-Based Complement Alternat Med, 2015, pp.603529~ (2015)[DOI]
  41. Xiao P, "Dietary silymarin supplementation promotes growth performance and improves lipid metabolism and health status in grass carp (Ctenopharyngodon idellus) fed diets with elevated lipid levels", Fish Physiol Biochem, 43, pp.245~263 (2017)[DOI]
  42. Yi D, "Effects of dietary silymarin supplementation on growth performance and oxidative status in Carassius auratus gibelio", J Animal Vet Adv, 11, pp.3399~3404 (2012)[DOI]
  43. Yin F, "Silibinin : A novel inhibitor of Aβ aggregation", Neurochem Int, 58, pp.399~403 (2011)[DOI]
  44. Zhang SP, "Effects of different dietary lipid level on the growth, survival and immune-relating genes expression in Pacific white shrimp, Litopenaeus vannamei", Fish Shellfish Immunol, 34, pp.1131~1138 (2013)[DOI]

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