담치에서 분리된 장염비브리오(Vibrio parahaemolyticus)의 유전체 서열 및 특성 분석
Genome Analysis and Characterization of Vibrio parahaemolyticus Isolated from Mussels
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Vibrio species are globally well-established as significant foodborne pathogens. These halophilic bacteria inhabit marine environments and pose risks to both marine ecosystems and human health. Vibrio parahaemolyticus is a leading cause of foodborne illness in humans, primarily through the consumption of contaminated seafood, and is associated with various virulence factors. Additionally, the presence of antibiotic resistance genes constitutes a significant risk factor. This study presents a comprehensive genomic analysis of the V. parahaemolyticus VP2406_85 strain isolated from mussels using next-generation sequencing to identify functional genes and proteins. The genome of the VP2406_85 strain comprises 5,299,256 bp and encompasses the virulence genes tdh, trh, and blaCARB-43, the latter of which encodes β-lactamase, a protein associated with antibiotic resistance. Genomic analysis highlighted the presence and variability of genes and traits that potentially contribute to pathogenicity and antimicrobial resistance. These characteristics of V. parahaemolyticus VP2406_85 provide valuable insights into its pathogenic profile, aiding in the development of improved strategies for food safety and public health surveillance.
Abstract
Vibrio species are globally well-established as significant foodborne pathogens. These halophilic bacteria inhabit marine environments and pose risks to both marine ecosystems and human health. Vibrio parahaemolyticus is a leading cause of foodborne illness in humans, primarily through the consumption of contaminated seafood, and is associated with various virulence factors. Additionally, the presence of antibiotic resistance genes constitutes a significant risk factor. This study presents a comprehensive genomic analysis of the V. parahaemolyticus VP2406_85 strain isolated from mussels using next-generation sequencing to identify functional genes and proteins. The genome of the VP2406_85 strain comprises 5,299,256 bp and encompasses the virulence genes tdh, trh, and blaCARB-43, the latter of which encodes β-lactamase, a protein associated with antibiotic resistance. Genomic analysis highlighted the presence and variability of genes and traits that potentially contribute to pathogenicity and antimicrobial resistance. These characteristics of V. parahaemolyticus VP2406_85 provide valuable insights into its pathogenic profile, aiding in the development of improved strategies for food safety and public health surveillance.