본문 바로가기
KERD
논문KCI 등재

조직은행에서 채취한 동종조직의 세균 배양 평가

Interpretation of bacterial contamination of allogeneic tissues obtained from cadaveric and living donors

0

조회

0

다운로드

1

인용

0

참고문헌

주제분류치의학

초록

Abstract

Thorough screening of donors medical and social history, extensive serological and bacterial screening combined with developed processing and sterilization methods have improved the safety of the allogeneic tissues in recent decades. The risk of bacterial infection through allogenic tissue transplantation is one of the major problems facing tissue banks. The purpose study is to report the contamination rate in 363 retrieved tissues obtained strictly aseptic conditions, between 2001 and 2002 in Korea Tissue Bank. Samples from 9 donors(total 13 donors) were used in blood culture, and in 7 donors the blood culture were negative. Of the 363 tissues cultured in their entirety, 186(51.2%) were initially culture negative and 177(48.8%) were positive. Organism low pathogenicity were cultures from 20.2% of the tissues. To minimize the bacterial load, donors should be obtain in operating rooms, using aseptic techniques with only a few personnel for procurement. The procurement cultures from donors and retrieved tissues with multiple should be carefully interpreted. Blood cultures should be taken account, since these can help to find contamination not detect swab culture. A prospective cohort study is needed to determine which of the varied processing and sterilization methodologies gives the best quality.

참고문헌 (29)

  1. "Reconstruction of massive bone defects with allograft in revision total knee arthroplasty", 79-a(1), pp.17~25 (1997)
  2. "Classification and reconstruction in revision acetabular arthroplasty with bone stock deficiency", 324, pp.98~107 (1996)
  3. "Impacted cancellous allografts and cement for revision total hip arthoplasty", 75-b, pp.14~21 (1993)
  4. "Results of onlay allografts", pp.108~12 (2000)
  5. "Revision of failed lumbar fusions A comparison of anterior autograft and allograft", pp.2748~55 (1997)
  6. "treatment with freeze-dried crushed cortical-bone allograft A review of one hundred and forty-four cases", pp.58 636~41
  7. "Infection in bone allografts", pp.70 369~76, Incidence
  8. "A study of the clinical incidence and causes of infection associated with their use", pp.72 1137~43
  9. "Abstract in New Millennium Workshop for Bone and Tissue Bank" (2000)
  10. "Microbiological monitoring of bone grafts:two years experience at a tissue bank", 38, pp.261~71 (1998)
  11. "The bacteriology of bone allografts", 74-b(3), pp.398~9 (1992)
  12. "Microbiologic and clinical value of primary broth cultures of wound specimens collected with swabs", 35(8), pp.2003~6 (1997)
  13. "Common standards for musculo-skelectal tissue banking" (1997)
  14. "High incidence of pathogenic microorganisms in bone allografts explanted in the morgue", 69(3), pp.311~4 (1998)
  15. "Sensitivity and negative predictive value of swab cultures in musculoskeletal allograft procurement", 300, pp.259~63 (1994)
  16. "sensitivity and negative predictive value of swab cultures in musculoskeletal allograft procurement", 300, pp.259~63 (1994)
  17. "임상병리검사지침", pp.37~38 (1998), 아주대학교병원 임상병리과
  18. "Clinical significance of microorganism recovered at autopsy", pp.28~40, Koneman EW
  19. "Selection of cases for culture", pp.17~23, Konema EW Minckler TM
  20. "Studies in postmortem bacteriology Necropsy sterility in three patients ad long ad thirty-five days postmortem", pp.12~6
  21. "Postmortem bacteriology", 1(1), pp.5~23 (1970)
  22. "Bacterial Contamination of Bone Allografts" (2002)
  23. "Dispersal of skin microorganisms", 93(4), pp.477~85 (1975)
  24. "A comparative study of blood and bone marrow cultures in cadaveric bone donation", 43(4), pp.305~8 (1999)
  25. "Transmission of disease through transplantation of musculoskeletal allogrfts", pp.77 1742~54
  26. "A review of allograft processing and sterilization techniques and their role in transmission of the human immunodeficiency virus", 21(2), pp.170~5
  27. "The effects of processing and low dose irradiation on cortical bone grafts", 375, pp.275~85 (2000)
  28. "Complication of irradiated allografts in orthopaedic tumor surgery", pp.214~7 (2000)
  29. "Intra-articular reaction associated with the use of freeze-dried ethylene oxide-sterilized bone-patella tendon-bone allografts in the reconstruction of the anterior cruciate ligament", pp.1~10

관련 논문AI추천

이 간행물의 다른 논문 (12건)