사람 면역결핍바이러스 감염과 동반된 특발 혈소판감소성 자색반병 1예
A Case of Idiopathic Thrombocytopenic Purpura in Patient with Human Immunodeficiency Virus Infection
0
조회
0
다운로드
0
인용
0
참고문헌
초록
사람 면역결핍바이러스 감염에 동반된 특발 혈소판감소성 자색반병은 약 4%에서 치명적인 출혈성 경향을 보이며 인체 면역기능의 변화로 치료를 선택함에 있어서 제약이 있을 수 있다. 본 증례의 환자는 prednisone과 IV immunoglobulin으로 치료하였으나 실패하였으며, 저자들은 항레트로바이러스제제와 prednisone을 병용투여하여 사람 면역결핍바이러스 감염에 동반된 특발 혈소판감소성 자색반병 1예를 성공적으로 치료하여 문헌고찰과 함께 보고하는 바이다.
Abstract
Thrombocytopenia is a common event in the course of human immunodef-iciency virus (HIV) infection. The maior cause of HIV virus related thrombocytopenia is idiopathic thrombocytopenic purpura (ITP). Treatment options for HIV related ITP are steroids, immunoglobulin, other immunosuppressive agents, and splenectomy. In addition, Antiretroviral agents are reported as effective treatment options in the setting of HIV-associated ITP, by enhancing CD4+ T cell counts, and reducing HIV viral loads. We report a case of HIV related ITP treated with prednisone, immunoglobulin, and highly active antiretroviral therapy (HAART).
참고문헌 (17)
- "Clinical study of hematoimmunologic features and opportunistic infetions of patients with AIDS", 52, pp.15~22 (1997)
- "Isolated thrombocytopenia in patient with HIV", 28, pp.79~84 (1988)
- "Infection of megakaryocytes by human immunodeficiency virus in seropositive patient with immune thrombocytopenic Purpura", 78, pp.1697~705 (1991)
- "Review of therapeutic options I HIV associated thrombocytopenia with emphasis on IV immunoglobulin treatment", 20, pp.223~9 (1991)
- "Hematoimmunologic findings in AIDS patients", 21, pp.65~65 (1997)
- "Hematologic abnormality in acquired immunodeficiency syndrome", 77, pp.224~8 (1984)
- "Common epitope on HIV p24 and human platelets", 342, pp.1274~5 (1993)
- "Initial observations on the efficacy of highly active antiretroviral therapy in the treatment of HIV associated autoimmune thrombocytopenia", 320, pp.117~23 (2000)
- "Anti-huma immunodeficiency virus type 1 antibody complex on platelets of seropositive thrombocytopenic homosexuals and narcotic addicts", 85, pp.9763~ (1988)
- "Anti-F(ab')2 antibodies in thrombocytopenic patient at risk for acquired immunodeficiency syndrome", 77, pp.1756~ (1986)
- "Presence of cross-reactive antibody between human immunodeficiency virus(HIV)and glycoproteins in HIV related immune thrombocytopenic purpura", 80, pp.162~9 (1992)
- "Cecil textbook of medicine" (2004)
- "Hemorrhagic sequelae of immune thrombocytopenic purpura in human immunodeficiency virus-infected hemophiliacs", 75, pp.1267~72 (1990)
- "Zidovudine for thrombocytopenic purpura related to human immunodeficiency virus(HIV)infection", 110, pp.365~8 (1989)
- "Treatment with megesterol acetate improves human immunodeficiency virus associated immune thrombocytopenia", 9, pp.583~7 (2002)
- "Rifampicin-induced thrombocytopenia", 56, pp.59~60 (1980)
- "Thrombocytopenic purpura associated with millary tuberculosis", 86, pp.976~980 (2003)