전투 경찰에서 A형 간염 발생률과 항체 양성률
Incidence and Seroprevalence of Hepatitis A Virus among Korean Auxiliary Police Officers
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목 적 : 우리나라에서 A형 간염은 표본 감시를 통해서 질병관리본부로 보고되고 있으나 전체 모집단을 규정할 수 없어 A형 간염 발생률을 조사하기는 어렵다. 이에 저자들은 단일 집단인 전투 경찰을 대상으로 연간 현증 A형 간염의 발생률 및 항체 양성률을 조사하고자 하였다. 재료 및 방법 : 의무기록 검색을 통하여 2002년부터 2006년까지 국립경찰병원에 입원하여 현증 A형 간염으로 진단된 전투 경찰을 조사하였다. 그리고 전투 경찰 507명을 대상으로 A형 간염 바이러스 항체를 검사하였다. 결 과 : 2002년부터 2006년까지 전투 경찰에서 연간 현증 감염의 발생률은 10만 명당 10.6-14.8명이었다. 건강한 전투 경찰의 A형 간염 바이러스 항체 양성률은 0.6% (3/ 507)이었다. 결 론 : 전투 경찰에서 연간 현증 A형 간염 발생률은 10만 명당 10명 이상이며, 전투 경찰의 A형 간염 항체 양성률은 1999년 30.2%에서 현재 0.6%로 현저히 낮아졌다. 전투 경찰에서 A형 간염 백신을 기본 접종할 것을 고려해야 한다.
Abstract
Background: In Korea, cases with hepatitis A have been reported to Korea Centers for Disease Control and Prevention through the sentinel surveillance system. However, it was difficult to study the exact nation-wide incidence of hepatitis A infection. We studied the incidence of clinically apparent hepatitis A infection and the seroprevalence of anti-HAV IgG among auxiliary police officers. Materials and methods: We analyzed clinically apparent and hospitalized hepatitis A patients from 2002 to 2006 in National Police Hospital via medical records. We also measured anti-HAV IgG antibody from 507 auxiliary police officers. Results: The estimated annual incidence of clinically apparent hepatitis A infection among auxiliary police officers was 10.6-14.8 cases per 100,000 population from 2002 to 2006. The overall anti-HAV IgG seropositive rate among auxiliary police officers was 0.6% (3/507). Conclusion: Among auxiliary police officers, the estimated annual incidence of clinically apparent hepatitis A infection was above 10 cases per 100,000 population and the positive rate of anti-HAV IgG was very low. The results were comparable to those in the low endemicity countries. The routine HAV vaccination among auxiliary police officers might be suggested.
참고문헌 (10)
- Kang CI, "Incidence and Seroprevalence of Hepatitis A Virus Infections among Young Korean Soldiers", 22, pp.546~548 (2007)
- Centers for Disease Control and Prevention, "Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on Immunization Practices(ACIP)", 48(RR-12), pp.1~37 (1999)
- Wasley A, "Incidence of hepatitis A in the United states in the era of vaccination", 294, pp.194~201 (2005)
- Jeong MH, "Adult Immunization", 68, pp.S20~S39 (2005)
- Song YB, "The Age-specific seroprevalence of hepatitis A virus antibody in Korea", 13, pp.27~33 (2007)
- Cha JY, "A seroepidemiological study of anti-HAV IgG in Korean combat policeman", 57, pp.988~993 (1999)
- Centers for Disease Control and Prevention, "Prevention of hepatitis A through active or passive immunization: recommendations of the Advisory Committee on Immunization Practices(ACIP)", 55(RR-7), pp.1~30 (2006)
- Pham B, "Seroprevalence of hepatitis A infection in a low endemicity country:a systematic review", 5(56) (2005)
- Cianciara J, "Hepatitis A shifting epidemiology in Poland and Eastern Europe", 18, pp.S68~S70 (2000)
- Han SH, "An Outbreak of Hepatitis A in South Korean Military Personnel:A Clinical and Epidemiologic Study", 7, pp.392~400 (2001)