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KERD
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천식에서 기도 상피세포의 역할

The Role of the Epithelial Cell in Bronchial Asthma

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Although traditionally viewed as a physical barrier between the host and a variety of inhaled irritants and pathogens, it has become clear that the epithelium has a much broader functional scope. Epithelial cells are metabolically active and can play an important role in the regulation of the allergic inflammatory response. This review preview provides a consideration of the role of the epithelial cell as both a "target" for exogenous and endogenous stimuli and as an "effector" cell that is capable of producing a variety of products that can influence the inflammatory response in the airways.

Abstract

Although traditionally viewed as a physical barrier between the host and a variety of inhaled irritants and pathogens, it has become clear that the epithelium has a much broader functional scope. Epithelial cells are metabolically active and can play an important role in the regulation of the allergic inflammatory response. This review preview provides a consideration of the role of the epithelial cell as both a "target" for exogenous and endogenous stimuli and as an "effector" cell that is capable of producing a variety of products that can influence the inflammatory response in the airways.

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