방사선조사에서 나노 입자 혼합물의 영향
The Effects of Nanoparticles for Irradiation
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Background To evaluate the changes in the radiation dose and temperature distribution on irradiated egg albumin and nanoparticle (Fe3O4) powder mixed egg albumin. Methods A new type of phantom was designed by fabricating a 30×30×30cm acryl square inside a 3×3×3cm small square and dividing it into two parts. In the control group, only egg albumin was irradiated, and in the test group, 25nm 20mg/cc, 25nm 40mg/cc, and 1 um 40 mg/cc nanoparticles with egg albumin were irradiated. The radiation isodose distributions and temperature changes were then observed. Results No significant changes were observed in the radiation dose and temperature distribution. Conclusion The nanoparticles were considered not to have had any effect on the radiation dose and temperature distribution under the experimental conditions. Further studies can be conducted based on the changes in the mixture material.
Abstract
Background To evaluate the changes in the radiation dose and temperature distribution on irradiated egg albumin and nanoparticle (Fe3O4) powder mixed egg albumin. Methods A new type of phantom was designed by fabricating a 30×30×30cm acryl square inside a 3×3×3cm small square and dividing it into two parts. In the control group, only egg albumin was irradiated, and in the test group, 25nm 20mg/cc, 25nm 40mg/cc, and 1 um 40 mg/cc nanoparticles with egg albumin were irradiated. The radiation isodose distributions and temperature changes were then observed. Results No significant changes were observed in the radiation dose and temperature distribution. Conclusion The nanoparticles were considered not to have had any effect on the radiation dose and temperature distribution under the experimental conditions. Further studies can be conducted based on the changes in the mixture material.
참고문헌 (15)
- Nishiyama N, "Nanomedicine : nanocarriers shape up for long life", Nat Nanotechnol, 2, pp.203~204 (2007)
- McNeil SE, "Nanoparticle therapeutics: a personal perspective", Wiley Interdiscip Rev Nanomed Nanobiotechnol, 1, pp.264~271 (2009)
- Eifler AC, "Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study", Methods Mol Biol, 726, pp.325~338 (2011)
- Hall JB, "Characterization of nanoparticles for therapeutics", Nanomedicine (Lond), 2, pp.789~803 (2007)
- Pankhurst QA, "Applications of magnetic nanoparticles in biomedicine", J Phys D: Appl Phys, 36, pp.R167~R181 (2003)
- Lee JH, "Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging", Nat Med, 13, pp.95~99 (2007)
- Jun YW, "Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging", J Am Chem Soc, 127, pp.5732~5733 (2005)
- Montet X, "Multivalent effects of RGD peptides obtained by nanoparticle display", J Med Chem, 49, pp.6087~6093 (2006)
- Geng B, "Egg albumin as a nanoreactor for growing single-crystalline Fe3O4 nanotubes with high yields", Chem Commun (Camb), pp.5773~5775 (2008)
- Peer D, "Nanocarriers as an emerging platform for cancer therapy", Nat Nanotechnol, 2, pp.751~760 (2007)
- Schild SE, "Radiotherapy treatment planning for prostate cancer in patients with prosthetic hips", Med Dosim, 17, pp.83~86 (1992)
- Carolan M, "Effect of hip prostheses on radiotherapy dose", Australas Radiol, 44, pp.290~295 (2000)
- Srivastava PK, "shock proteins come of age: primitive functions acquire new roles in an adaptive world", Immunity, 8, pp.657~665 (1998)
- Ma M, "Size dependence of specific power absorption of Fe3O4 particles in AC magnetic field", J Magn Magn Mater, 268, pp.33~39 (2004)
- Keall PJ, "Radiotherapy dose calculations in the presence of hip prostheses", Med Dosim, 28, pp.107~112 (2003)