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참꽃마리(Trigonotis radicans var. sericea) 전초 유래 페놀성 추출물의 항산화, 항염증, 피부주름 생성 억제 및 미백 효과

The inhibitory activity against oxidation, inflammation, wrinkle, and melanin production by phenolic extracts from Trigonotis radicans var. sericea

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The objective of this study was to assess the inhibition activity oxidation, inflammation, wrinkle, and melanin production of water and ethanol extracts from Trigonotis radicans var. sericea. (TRS). The antioxidant potential was measured using DPPH, ABTS, antioxidant protection factor, and TBARS assays. The extracts showed excellent antioxidant abilities at the 100 μg/mL total phenolic contents (TPC) concentration. Both distilled water extract (TRSW) and 60% ethanol extract (TRSE) showed high hyaluronidase inhibition activity at 400 μg/mL TPC concentration. The TRSW and TRSE showed 15.06% and 27.82% inhibition on elastase, 55.15% and 51.70% inhibition on collagenase at concentration of 400 µg/mL. The tyrosinase inhibition was 27.52% at 400 μg/mL phenolic extracts in TRSE. Therefore, this extract is considered to have high anti-aging effects. Furthermore, TRS extract has potential as a functional beauty food ingredient.

Abstract

The objective of this study was to assess the inhibition activity oxidation, inflammation, wrinkle, and melanin production of water and ethanol extracts from Trigonotis radicans var. sericea. (TRS). The antioxidant potential was measured using DPPH, ABTS, antioxidant protection factor, and TBARS assays. The extracts showed excellent antioxidant abilities at the 100 μg/mL total phenolic contents (TPC) concentration. Both distilled water extract (TRSW) and 60% ethanol extract (TRSE) showed high hyaluronidase inhibition activity at 400 μg/mL TPC concentration. The TRSW and TRSE showed 15.06% and 27.82% inhibition on elastase, 55.15% and 51.70% inhibition on collagenase at concentration of 400 µg/mL. The tyrosinase inhibition was 27.52% at 400 μg/mL phenolic extracts in TRSE. Therefore, this extract is considered to have high anti-aging effects. Furthermore, TRS extract has potential as a functional beauty food ingredient.

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