A Case of Therapy-Related Acute Leukemia With Mixed Phenotype With BCR-ABL1 After Treatment of Diffuse Large B-Cell Lymphoma
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Dear Editor, Although therapy-related acute leukemia (tAL) is a well-recognized clinical syndrome and is increasing owing to the prolonged survival of patients treated with chemoradiotherapy [1], tAL with mixed phenotype is extremely rare. Only four cases of tAL with mixed phenotype have been reported worldwide; among them, only one case occurred after hematologic malignancy [2, 3]. Here, we report a rare case of tAL with mixed phenotype with BCR-ABL1 after achieving complete remission (CR) of diffuse large B-cell lymphoma (DLBCL).
Abstract
Dear Editor, Although therapy-related acute leukemia (tAL) is a well-recognized clinical syndrome and is increasing owing to the prolonged survival of patients treated with chemoradiotherapy [1], tAL with mixed phenotype is extremely rare. Only four cases of tAL with mixed phenotype have been reported worldwide; among them, only one case occurred after hematologic malignancy [2, 3]. Here, we report a rare case of tAL with mixed phenotype with BCR-ABL1 after achieving complete remission (CR) of diffuse large B-cell lymphoma (DLBCL).
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