본문 바로가기
KERD
논문KCI 등재

돌연변이체로부터 α-glucosidase 저해활성이 높은 계통의 선발

Screening of High α-Glucosidase Inhibitor Line in Pepper (Capsicum annuum L.) Mutants

2

조회

0

다운로드

0

인용

0

참고문헌

주제분류농학

초록

Abstract

This study was carried out to screen high α-glucosidase inhibitor (AGI) activity pepper lines from EMS treated mutants of pepper. The optimal concentration of EMS for inducing mutants to pepper was 0.15M and the optimal treatment time of EMS was 2 hours. With this condition, many mutants which have high AGI activity were screened and especially leaf of two lines were showed 27 times inhibitory activity on α-glucosidase comparing with control. There is no difference between mutants and nornmal plant in growth. These results indicated that AGI activity of pepper leaf would be increased by mutation.

참고문헌 (21)

  1. De Fronzo RA, "Pharmacologic therapy for type 2 diabetes mellitus", 131, pp.281~303 (1999)
  2. Govindarajan, "Capsicum-production, technology, chemistry, and quality. part Ⅲ. chemistry of the color, aroma, and pungency stimuli, CRC Crit", pp.245~355
  3. Gray DM, "Carbohydrate digestion and absorption role of small intestine", 29, pp.1225~1230 (1995)
  4. "and Koinvistoninen P. 1982. Food technological evaluation of xylitol. Adv. Food. Res.", pp.373~403
  5. "and Jentzsci K. 1979. Identification of cultivated YAXA of capsicum-taxanomy anatomy and composition of pungent principles. plant. Med. Plant RES. 35", pp.174~181
  6. Kim KJ, "Production of α-Glucosidase inhibitor by β-Glucosidase inhibitor-producing Bacillus lentimorbus B-6.", 12, pp.895~900 (2002)
  7. Kim SH, "Comparision of glucose-lowering activity of the extracts from Kangwon-do mountain mulberry leaves (Moli foliam) and silk worm", 25, pp.391~395 (1997)
  8. Kim SK, "Studies on the inhibitory effect of Eugenia aromaticum extract on pancreatic lipase", 48(2), pp.84~88 (2005)
  9. Kim YM, "Inhibitory effect of pine extract on α-glucosidase activity and postprandial hyperglycemia", 21, pp.756~761 (2005)
  10. Krentz AJ, "Oral antidiabetic agents: Current role in type 2 diabetes mellitus", 65, pp.385~411 (2005)
  11. Kwon YI, "Clonal herbs of Lamiaceae species against diabetes and hypertension", 15, pp.107~118 (2006)
  12. McCue P, "Inhibitory effects of rosmarinic acid extracts on porcine pancreatic amylase in vitro.", 13, pp.101~106 (2004)
  13. "Moore FW. 1970. Food habits in non-industrial societies in dimensions of Nutrition. Dupnt. J. Ed. Colorado Associated University press."
  14. In, "Pickersgill B. 1969. The domestication of chilli peppers in the domestication and exploitation of plants and animals"
  15. Puls HP, "and Thomas G. 1984. Inhibitors of the rate of carbohydrate and lipid absorption by the intestine. Int. J. Obesity. 8"
  16. Bay d7791, "Puls W and Keup U. 1973. Influence of an α-amylase inhibitor serum insulin and NEFF in starch loading tests in rats", pp.97~101
  17. Rury RH, "A randomized double-blind trial of Acarbose in type 2 diabetes shows improved glycaemic control over 3 years", 22, pp.960~964 (1999)
  18. Saito N, "Effect of a α-glucosidase inhibitor (Voglibose)", 26, pp.219~232 (1998)
  19. "Singh RK. 1994. Research direction for food engineering. J. Food Eng.", pp.491~499
  20. "Tattersall R. 1993. α-glucosidase inhibition as an adjunt to the treatment of type I diabetes. Diabetic medicine. 10", pp.668~672
  21. Toeller M, "Nutritional intake of 2868 IDDM patients from 30 centres in Europe", 39, pp.929~939 (1996)

관련 논문AI추천

이 간행물의 다른 논문 (37건)