파장가변 빛간섭단층촬영기와 저간섭성 반사계, 초음파, 자동굴절검사기로 측정한 안구계측 비교
Comparison of Ocular Biometric Measurements Using New Swept-source Optical-coherence Tomography, Low-coherence Reflectometry, A-Scan Biometry, and Autokeratometry
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초록
목적: Anterion®으로 측정한 안구 생체계측과 Lenstar LS900®, Essilor AKR 750®, PacScan300A®로 측정한 안구계측을 비교하여Anterion®의 유용성을 알아보고자 하였다. 대상과 방법: 환자 47명, 86안을 선정하여 Anterion®, Lenstar®로 안축장, 수정체두께, 중심각막두께, 전방깊이, 각막곡률, AKR 750® 으로 각막곡률, PacScan 300A®로 안축장을 측정 후, 차이값과 상관관계를 확인했으며, 급내상관계수와 Bland-Altman plot으로 일치도를 분석하였다. 결과: Anterion®, Lenstar®로 측정한 안축장, 수정체두께, 중심각막두께, 전방깊이, 각막윤부직경은 -0.02 ± 0.08, 0.08 ± 0.13, -2.66 ± 11.12, 0.05 ± 0.12, 0.08 ± 0.26으로 유의미한 차이를 보였다. Anterion®과 Lenstar®로 측정한 평균 각막굴절력은 -0.08 ± 0.47로 유의미한 차이를 보인 반면, AKR 750®와 비교했을 때는 차이가 없었다. Anterion®의 측정값은 다른 기기의 측정값과 피어슨상관계수를 검증했을 때 강한 양의 상관관계를 보였고 급내상관계수, Bland-Altman plot에서 높은 일치도를 보였다. 결론: Anterion®은 기존 기기들과 비교했을 때 차이의 절대값은 크지 않으나, Lenstar®의 경우 통계적으로 유의한 차이를 보인 지표들이 있었다. 백내장수술에서 인공수정체를 결정하는 등 임상 적용 시 기존 기기와 다른 결과를 만들 수 있기 때문에 주의할 필요가있다.
Abstract
Purpose: We compared optical biometric measurements made using new swept-source optical-coherence tomography, low-coherence reflectometry, autokeratometry, and A-scan biometry. Methods: In total, 86 eyes of 47 patients were included. Axial length, lens thickness, central corneal thickness, anterior chamber depth, and corneal curvature were measured using the Anterion® (Heidelberg Engineering, inc., Heidelberg, Germany) and Lenstar LS 900® (Haag-Streit AG, Koeniz, Switzerland) platforms. Corneal curvature and axial length were measured using the Essilor AKR 750® (Essilor instruments, France, Charenton-le-Pont) and PacScan 300A® (Sonomed Inc., Chicago, IL, USA) platforms, respectively. The evaluated biometric parameters were compared and verified; intraclass correlation coefficients and Bland-Altman plots were used to analyze statistical agreement. Results: The differences between the Anterion® and Lenstar LS 900® platforms in terms of axial length, lens thickness, central corneal thickness, anterior chamber depth, and white-to-white diameter were -0.02 ± 0.08, 0.08 ± 0.13, -2.66 ± 11.12, 0.05 ± 0.12, and 0.08 ± 0.26, respectively. All values were statistically significant. The mean corneal curvature between Anterion® and Lenstar LS 900® had a statistically significant difference of -0.08 ± 0.47, while the difference between the Anterion® and AKR 750® platforms was not significant. Biometric parameters measured using an Anterion® and other devices showed a strong positive correlation when assessed using Pearson’s correlation analysis; there was good agreement between the results when analyzed using intraclass correlation coefficients and Bland-Altman plots. Conclusions: Optical biometric measurements made using the Anterion® platform were not significantly different from those obtained using other devices, but there were significant differences compared to the Lenstar LS 900® platform. Since these significant differences could influence decision making during intraocular lens selection for cataract surgery, the values are clinically useful for reference.
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