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Evaluation of antimicrobial effects of commercial mouthwashes utilized in South Korea

김재홍|이아라|오세환|전준호|백순영|양수정|한상하|손미원
생화학분자생물학회 (Korean Society Of Biochemistry And Molecular Biology)|2015.01|BMB Reports|제48권 제1호|pp. 42-47

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참고문헌

키워드

Antibacterial activityStreptococcus mutansMouthwashesCetylpyridinium chloride
주제분류화학

초록

Streptococcus mutans is frequently associated with dentalcaries. Bacterial fermentation of food debris generates anacidic environment on the tooth surface, ultimately resulting intooth deterioration. Therefore, various mouthwashes havebeen used to reduce and prevent Streptococcus mutans. Theaim of this study was to evaluate the antimicrobial activities of4 commercial mouthwashes and those of 10% and 20%ethanol solutions (formula A, B, C, D, E and F) againstStreptococcus mutans using biofilm and planktonic methods. The range of reduction in the viable cell count of Streptococcusmutans as estimated by the biofilm and planktonic methodswas 0.05-5.51 log (P ≤ 0.01) and 1.23-7.51 log (P ≤ 0.001)compared with the negative control, respectively, indicatingthat the planktonic method had a stronger antibacterial effectagainst S. mutans. Among the tested formulations, formula A(Garglin regularⓇ mouthwash) was the most effective againstStreptococcus mutans (P ≤ 0.001).

Abstract

Streptococcus mutans is frequently associated with dentalcaries. Bacterial fermentation of food debris generates anacidic environment on the tooth surface, ultimately resulting intooth deterioration. Therefore, various mouthwashes havebeen used to reduce and prevent Streptococcus mutans. Theaim of this study was to evaluate the antimicrobial activities of4 commercial mouthwashes and those of 10% and 20%ethanol solutions (formula A, B, C, D, E and F) againstStreptococcus mutans using biofilm and planktonic methods. The range of reduction in the viable cell count of Streptococcusmutans as estimated by the biofilm and planktonic methodswas 0.05-5.51 log (P ≤ 0.01) and 1.23-7.51 log (P ≤ 0.001)compared with the negative control, respectively, indicatingthat the planktonic method had a stronger antibacterial effectagainst S. mutans. Among the tested formulations, formula A(Garglin regularⓇ mouthwash) was the most effective againstStreptococcus mutans (P ≤ 0.001).

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