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Vitamin A: a key coordinator of host-microbe interactions in the intestine

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초록

The human intestine is home to a dense community of microbiotathat plays a key role in human health and disease. Nutrientsare essential regulators of both host and microbial physiologyand function as key coordinators of host-microbe interactions. Therefore, understanding the specific roles and underlying mechanismsof each nutrient in regulating the host-microbe interactionswill be essential in developing new strategies for improvinghuman health through microbiota and nutrient intervention. This review will give a basic overview of the role of vitaminA, an essential micronutrient, on human health, and highlightrecent findings on the mechanisms by which it regulatesthe host-microbe interactions.

Abstract

The human intestine is home to a dense community of microbiotathat plays a key role in human health and disease. Nutrientsare essential regulators of both host and microbial physiologyand function as key coordinators of host-microbe interactions. Therefore, understanding the specific roles and underlying mechanismsof each nutrient in regulating the host-microbe interactionswill be essential in developing new strategies for improvinghuman health through microbiota and nutrient intervention. This review will give a basic overview of the role of vitaminA, an essential micronutrient, on human health, and highlightrecent findings on the mechanisms by which it regulatesthe host-microbe interactions.

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