토모테라피에서 쌀 볼루스 팬텀의 유용성 평가: 팬텀연구
Evaluating the Usefulness of Rice Bolus Phantom in Tomotherapy: Phantom Study
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
The purpose of this study was to evaluate the usefulness of the rice bolus for upper-lower extremity radiation therapy by Tomotherapy. The computed tomography images were obtained for air, water, and rice bolus. The average and standard deviation of the Hounsfield unit (HU) were measured for image evaluation. The conformity index (CI) and homogeneity index (HI) were calculated for dose distribution of the planning target volume (PTV) which was treated by direct mode with gantry angle (90 and 270 angle). The point dose of a total of ten axial planes was measured to confirm the different regions. The mean of HU was -999.72 ± 0.72 at the air. The water and rice bolus were -0.13 ± 1.65 and -170 ± 27.2, respectively. The CI (HI) of PTV was 0.96 (1.36) at the air. 0.95 (1.04) at the water bolus, and 0.95 (1.04) at the rice bolus. The maximum dose for air was 136 cGy which is about 32% higher than 103 cGy for water and 104 cGy for rice bolus. There was a statistical difference for point dose between air and water including rice bolus (p=0.04), however, no statistical difference between water and rice bolus (p=0.579).The rice bolus phantom for extremities radiation therapy could be not only the optimized dose distribution but also the convenience and equipment safety at Tomotherapy. However, additional research will be necessary to more accurately verify the clinical usefulness of rice bolus phantom due to not enough examination.
Abstract
The purpose of this study was to evaluate the usefulness of the rice bolus for upper-lower extremity radiation therapy by Tomotherapy. The computed tomography images were obtained for air, water, and rice bolus. The average and standard deviation of the Hounsfield unit (HU) were measured for image evaluation. The conformity index (CI) and homogeneity index (HI) were calculated for dose distribution of the planning target volume (PTV) which was treated by direct mode with gantry angle (90 and 270 angle). The point dose of a total of ten axial planes was measured to confirm the different regions. The mean of HU was -999.72 ± 0.72 at the air. The water and rice bolus were -0.13 ± 1.65 and -170 ± 27.2, respectively. The CI (HI) of PTV was 0.96 (1.36) at the air. 0.95 (1.04) at the water bolus, and 0.95 (1.04) at the rice bolus. The maximum dose for air was 136 cGy which is about 32% higher than 103 cGy for water and 104 cGy for rice bolus. There was a statistical difference for point dose between air and water including rice bolus (p=0.04), however, no statistical difference between water and rice bolus (p=0.579).The rice bolus phantom for extremities radiation therapy could be not only the optimized dose distribution but also the convenience and equipment safety at Tomotherapy. However, additional research will be necessary to more accurately verify the clinical usefulness of rice bolus phantom due to not enough examination.
참고문헌 (25)
- Khan FM, "Khan’s the physics of radiation therapy", pp.1~570 (2014), Lippincott Williams & Wilkins
- 김성우, "Clinical Implementation of 3D Printing in the Construction of Patient Specific Bolus for Photon Beam Radiotherapy for Mycosis Fungoides", 의학물리, 28(1), pp.33~38 (2017), 한국의학물리학회[DOI]
- Majithia L, "Treating cutaneous T-cell lymphoma with highly irregular surfaces with photon irradiation using rice as tissue compensator", Front Oncol., 5(49) (2015)
- Nicolini G, "Critical appraisal of volumetric-modulated arc therapy compared with electrons for the radiotherapy of cutaneous Kaposi's sarcoma of lower extremities with bone sparing", Br J Radiol, 86(1023), pp.20120543~ (2013)
- 서정민, "사지의 방사선 치료에 사용하는 water bolus의 적용 시 치료부위의 위치 변화에 따른 방사선 선량분포의 민감도 연구", 대한안전경영과학회지, 17(4), pp.199~206 (2015), 대한안전경영과학회[DOI]
- Lee HH, "Evaluation of a colloid gell(Slime) as a body compensator for radiotherapy", J Korea Soc Radiat Ther, 30(1,2), pp.191~199 (2018)
- Butson MJ, "Effects on skin dose from unwanted air gaps under bolus in photon beam radiotherapy", Radiat Meas, 32(3), pp.201~204 (2000)
- 안승권, "사지에 발병한 카포시육종의 방사선치료를 위한 물볼루스 기구의 유용성 고찰", Radiation oncology journal, 26(3), pp.189~194 (2008), 대한방사선종양학회
- Jeon DM, "Evaluation of the usefulness of a rice compensator fixing device applied to the treatment of chloroma metastasized to the upper extremity", Korean Associ Radiat Protec, pp.20~21 (2011)
- Lee H, "Water bath radiation for extensive, extremity-based cutaneous disease of mycosis fungoides", Adv Radiat Oncol, 5(6), pp.1370~1374 (2020)
- 조강철, "토모테라피를 이용한 3차원 입체 조형 치료의 임상적 적용 분석", 방사선기술과학, 36(4), pp.327~335 (2013), 대한방사선과학회
- 강동진, "비 인두암 체적 조절 호형 방사선 치료의 선량 계산 격자 크기에 따른 선량 체적 지수와 방사선 생물학적 지수의 평가", 방사선기술과학, 43(4), pp.265~272 (2020), 대한방사선과학회
- Kim TW, "Evaluation of the usefulness for VMAT of multiple brain metastasis using jaw tracking", J Korea Soc Radiat Ther, 30, pp.73~81 (2018)
- Lim JH, "Comparison and evaluation of radiotherapy plans by multi leaf collimator types of linear accelerator", J Korea Soc Radiat Ther, 30(1,2), pp.129~138 (2018)
- Xu Y, "Dosimetric comparison of the helical Tomotherapy, Volumetric-modulated arc therapy and fixed-field intensity-modulated radiotherapy for stage IIB-IIIB non-small cell lung cancer", Sci Rep, 7(1), pp.1~9 (2017)
- Kataria T, "Homogeneity Index : An objective tool for assessment of conformal radiation treatments", J Med Phys, 37(4), pp.207~213 (2012)
- Podgorsak EB, "Radiation Physics for Medical Physicists. Vol. 1" (2006), Springer
- Moyer RF, "A surface bolus material for high-energy photon and electron therapy", Radiology, 146(2), pp.531~532 (1983)
- Bahhous K, "Enhancing benefits of bolus use through minimising the effect of air-gaps on dose distribution in photon beam radiotherapy", Journal of Radiotherapy in Practice, 20(2), pp.210~216 (2021)
- Miescke A, "Bolus in radiation therapy : The versatility of water", Radiat Therap, 25(1), pp.22~27 (2016)
- 서정민, "사지의 방사선치료에 사용되는 쌀 볼루스의 품종에 따른 방사선량분포의 민감도 연구", 한국방사선학회논문지, 14(6), pp.741~746 (2020), 한국방사선학회[DOI]
- Borca VC, "Does TomoDirect 3DCRT represent a suitable option for post-operative whole breast irradiation? A hypothesis-generating pilot study", Radiat Oncol, 7(1), pp.1~10 (2012)
- Kim SW, "Clinical implementation of a wide-field electron arc technique with a scatterer for widespread Kaposi's sarcoma in the distal extremities", Scientific Reports, 10(1), pp.1~11 (2020)
- Potter A, "A technique for treating extended skin field cancerisation using volumetric modulated arc therapy", Int J Radiol Radiat Ther, 6(4), pp.111~119 (2019)
- Obeid JP, "Volumetric modulated arc therapy and 3-dimensional printed bolus in the treatment of refractory primary cutaneous gamma delta lymphoma of the bilateral legs", Prac Radiat Oncol, 9(4), pp.220~225 (2019)