위상대조도 자기공명영상을 이용한 심장 혈류평가에 있어서 호흡정지기법과 비 호흡정지 기법의 비교평가
The Assessment of the Breath Hold and the Free Breath Methods about the Blood Flow Evaluation by Using Phase Contrast MRI
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자기공명영상을 이용한 심장혈류의 측정은 호흡과 심장의 불수의적인 움직임으로 인해 제한되어 왔다. 따라서 본 연구에서는 심장혈류의 측정값을 비교하여 적절한 호흡방법과 영상변수를 제시하고 위상대조도 자기공명영상을 통한 심장혈류검사의 정확성을 향상시키고자 하였다. 연구 대상자는 정상의 지원자 15명(남: 10명, 여: 5명) 평균연령: 30±5.2세를 대상으로 하였다. 상행대동맥과 하행대동맥에서 위상대조도 자기공명영상을 이용하여 각각 호흡정지 retrospective 1NEX와 비 호흡정지 retrospective 1-3NEX로 검사하여 비교하여 평가하였다. 연구 결과 상행대동맥에서 호흡정지 retrospective 1NEX의 평균혈류량/평균혈류속도는 각각 96.17±19.12ml/sec, 17.04±4.12cm/sec로 비 호흡정지 retrospective 1NEX의 72.31±13.27ml, 12.32±3.85cm/sec와는 통계적으로 유의한 차이를 보였다(p<0.05). 반면에 2NEX에서는 평균혈류량과 평균혈류속도가 101.90±24.09, 16.84±4.32, 3NEX 에서는 103.06±25.49, 16.88±4.19로 통계적으로 유의한 차이를 보이지 않았다(p>0.05). 하행대동맥에서 호흡정지 retrospective 1NEX의 평균혈류량/평균혈류속도는 76.68±19.72ml/sec, 22.23±4.8cm/sec로 비 호흡정지retrospective 1-3NEX와 비교 시 유의한 차이를 보이지 않았다. 그러므로 비 호흡정지 retrospective방법은 NEX의증가에 따라 호흡정지 retrospective방법과 비교하여 심장혈류 측정값에 유의한 차이점이 없기 때문에 숨을 잘 참지 못하거나 또는 소아환자에게 있어서 심장혈류 검사의 진단적 가치를 높여줄 것으로 사료된다.
Abstract
Measurement of cardiac blood flow using the magnetic resonance imaging has been limited due to breathing and involuntary movements of the heart. The present study attempted to improve the accuracy of cardiac blood flow testing through phase contrast magnetic resonance imaging by presenting the adequate breathing method and imaging variables by comparing the measurement values of cardiac blood flow. Each was evaluated by comparing the breath hold retrospective 1NEX and non breath hold retrospective 1-3NEX in the ascending aorta and descending aorta. As a result, the average blood flow amount/ velocity of the breath hold retrosepctive 1NEX method in the ascending aorta were 96.17±19.12ml/sec, 17.04±4.12cm/sec respectively, which demonstrates a statistically significant difference(p<0.05) with the non-breath hold retrospective method 1NEX of 72.31±13.27ml and 12.32±3.85. On the other hand, the average 2NEX blood flow and mean flow velocity is 101.90±24.09, 16.84±4.32, 3NEX 103.06±25.49,16.88±4.19 did not show statistically significant differences(p>0.05).The average blood flow amount/ velocity of the breath hold retrospective 1NEX method in the descending aorta were 76.68±19.72ml/s, and 22.23±4.8, which did not demonstrate a significant difference in comparison to non-breath hold retrospective method 1-3 NEX. Therefore, the non breath hold retrospective method does not significantly differ in terms of cardiac blood flow in comparison with the breath hold retrospective method in accordance with the increase of NEX, so pediatric patients or patients who are not able to breathe well must have the diagnostic value of their cardiac blood flow tests improved.
참고문헌 (20)
- Higgins, Charles B., "Functional evaluation of the heart with magnetic resonance imaging", Magnetic resonance in medicine, 6(2), pp.121~139 (1988)
- Zhang, Shuo, "Real-time magnetic resonance imaging of cardiac function and flow—recent progress", Quantitative imaging in medicine and surgery, 4(5), pp.313~329 (2014)
- Weiger, Markus, "Cardiac real‐time imaging using SENSE", Magnetic Resonance in Medicine, 43(2), pp.177~184 (2000)
- Maier SE, "Human abdominal aorta : comparative measurements of blood flow with MR imaging and multigated doppler US", Radiology, 171, pp.487~492 (1989)
- Donald W, "MRI From Picture to Proton", pp.269~ (2006)
- Joachim Lotz, "Cardiovascular Flow Measurement with Phase- Contrast MR Imaging : Basic Facts and Imple mentation", RSNA, 22, pp.651~671 (2002)
- O'Donnell M, "NMR blood flow using multiecho, phase contrast sequences", Med Phys, 12, pp.59~64 (1985)
- Singer JR, "Blood flow rates by NMR measurements", Science, 130, pp.1652~1653 (1959)
- Sakuma H, "MR measurement of coronary blood flow", J Magn Reson Imaging, 10, pp.728~733 (1999)
- Steffens JC, "Quantification of collateral blood flow in coarctation of the aorta by velocity encoded cine magnetic resonance imaging", Circulation, 90, pp.937~943 (1994)
- Kayser HW, "MR velocity mapping of tricuspid flow: correction for through-plane motion", J Magn Reson Imaging, 7, pp.669~673 (1997)
- Hundley WG, "Magnetic resonance imaging assessment of the severity of mitral regurgitation: comparison with invasive techniques", Circulation, 92, pp.1151~1158 (1995)
- Spritzer CE, "Rapid MR imaging of blood flow with a phase-sensitive, limited-flip-angle, gradient recalled pulse sequence: preliminary experience", Radiology, 176, pp.255~262 (1990)
- O'Donnell M, "NMR blood flow imaging using multiecho, phase contrast sequences", Med Phys, 12, pp.59~64 (1985)
- Evans AJ, "Magnetic resonance imaging of blood flow with a phase subtraction technique:In vitro and in vivo validation", Invest Radiol, 28, pp.109~115 (1993)
- Ferringno M, "Cardiac performance in humans during breath-holding", J Appl Physiol, pp.1871~2817 (1986)
- Rominger MB, "Comparison between biventricular cine MRI and MR flow quantification in ascending aorta and pulmonary outflow tract for the assessment of intracardial shunt volumes", Fortschr Rontgenstr, 174, pp.1380~1386 (2002)
- Rominger MB, "Biventricular MRvolumetric analysis and MR flow quantification in the ascending aorta and pulmonary trunk for quantification of valvular regurgitation", Fortschr Rontgenstr, 176, pp.342~349 (2004)
- "Abdominal phase-contrast MR angiography:breath-hold versus non-breath-hold techniques", J Magn Reson Imaging, 6(1), pp.94~98 (1996)
- Yang, Roberta K., "Optimizing Abdominal MR Imaging: Approaches to Common Problems 1", Radiographics, 30(1), pp.185~199 (2010)