환아의 혈액과 변에서 분리된 Shigella flexneri의 생화학적 성상, 항균제 감수성 및 Pulsed-Field Gel Electrophoresis 분석
Biochemical Characteristics, Antimicrobial Susceptibility and Pulsed-Field Gel Electrophoresis Patterns of Shigella flexneri Isolated from Blood and Fecal Specimens of Pediatric Patients
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Abstract
Shigellosis is the most common bacterial gastroenteritis both in developing and developed countries, but bacteremia due to Shigella spp. is very rare. In developed countries recent shigellosis is mostly caused by S. sonnei, but S. flexeri infection is rare. We had rare cases of S. flexeri infections in a family in the Jeonbuk Province: an 8-year-old boy with bacteremic shigellosis and 10- and 12-year-old brothers with diarrhea. The isolates had identical biochemical characteristics, and were resistant to ampicillin, chloramphenicol, and co-trimoxazole. PFGE pattern of NotⅠ-restricted genomic DNA suggested that the isolate from blood was closely related to the two strains isolated from stool which had an identical PFGE pattern.