Effects of Korean Citrus junos and Medicinal Herbs on Liver protection and lipid metabolism of Alcohol Fed rats
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Abstract
- In order to investigate whether or not the alcohol -treated rat liver cells canbe protected by Korean Citrus junos and medicinal herbs, We compared the serumbiochemistry of rats administered both alcohol and the complex of Korean Citrus junosand medicinal herbs to control rats treated with alcohol alone. The activities of Aspar-tate aminotransferase(AST) and Alanine aminotransferase(ALT) in the citron 3(Citron3, less mellowed citron which was ripened for three months) ± Phellinus linteus, Alnusjaponica, Dendropanax morbifera and citron 4 (Citron 4, completely mellowed citronwhich was ripened for four months) ± Phaseolus radiatus, Cordyceps militaris groupwere significantly low when compared with the negative control group (p 0.05). Thelevels of triglyceride (TG) in all experimental groups were significantly lower than thenegative control group (p 0.05). The concentrations of total cholesterol in the citron3± Phellinus linteus, Alnus japonica, Dendropanax morbifera and citron 4 ± Phaseolusradiatus, Cordyceps militaris, Phellinus linteus were lower than the negative controlgroup (p 0.05). The activities of alcohol dehydrogenase (ADH) in all experimentalgroups were significantly high when compared with the normal control group (p 0.05).These results suggest that the complex of Korean Citrus junos and medecinal herbscould be an excellent candidate for protecting rat liver cell damage induced by alcohol.
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