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논문KCI 등재

소아 장간막 림프절염의 경구 한약 치료에 대한 최신 중의학 임상연구 동향: 체계적 문헌고찰

Recent Trends in Traditional Chinese Medicine Clinical Research of Oral Herbal Medicine Treatment for Mesenteric Lymphadenitis in Children: A Systemic Review

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Objectives The purpose of this study is to analyze the trends of Chinese clinical research in the last 4 years of Chinese herbal medicine treatment for mesenteric lymphadenitis in children. Methods From 2020 to 2023, published literature was searched by China National Knowledge Infrastructure. Demographic data, duration of illness, diagnostic method, intervention, treatment duration, outcome, and adverse events were analyzed. Results A total of 19 RCTs were analyzed. In all studies that conducted the total efficacy rate of the treatment group was significantly higher than that of the control group. In addition, we compared laboratory tests, the diameter of lymph nodes using ultrasound, the duration of major symptom disappearance, chinese symptom score, and recurrence rate before and after treatment. In general, the treatment group showed a statistically significant treatment effect than the control group (p < 0.05). Conclusions In all studies, herbal medicine treatment was effective in treating pediatric mesenteric lymphadenitis, but more elaborately designed studies are needed for efficacy and safety assessment.

Abstract

Objectives The purpose of this study is to analyze the trends of Chinese clinical research in the last 4 years of Chinese herbal medicine treatment for mesenteric lymphadenitis in children. Methods From 2020 to 2023, published literature was searched by China National Knowledge Infrastructure. Demographic data, duration of illness, diagnostic method, intervention, treatment duration, outcome, and adverse events were analyzed. Results A total of 19 RCTs were analyzed. In all studies that conducted the total efficacy rate of the treatment group was significantly higher than that of the control group. In addition, we compared laboratory tests, the diameter of lymph nodes using ultrasound, the duration of major symptom disappearance, chinese symptom score, and recurrence rate before and after treatment. In general, the treatment group showed a statistically significant treatment effect than the control group (p < 0.05). Conclusions In all studies, herbal medicine treatment was effective in treating pediatric mesenteric lymphadenitis, but more elaborately designed studies are needed for efficacy and safety assessment.

참고문헌 (42)

  1. Park CH, "Clinical observation of mesenteric lymphadenitis in children", Korean J Pediatr, 47(1), pp.31~35 (2004)
  2. Koo EJ, "Hanbangsoacheongsonyeonuihak", pp.352~353 (2020), Ui Sung Dang Publishing Co
  3. Helbling R, "Acute nonspecific mesenteric lymphadenitis : more than"no need for surgery"", Biomed Res Int, 2017(1), pp.1~2 (2017)
  4. Özdamar MY, "Acute mesenteric lymphadenitis in children : findings related to differential diagnosis and hospitalization", Arch Med Sci, 16(2), pp.313~320 (2018)
  5. Doğan O, "Evaluation of children diagnosed with mesenteric lymphadenitis by ultrasonography", Acad J Health, 1(1), pp.9~15 (2023)
  6. Vinay SSG, "Mesenteric lymphadenopathy in children with chronic abdominal pain-a single center retrospective case control study from a tertiary care center in puducherry", J Evid Based Med Healthc, 8(21), pp.1664~1667 (2021)
  7. Lee JH, "The etiology and clinical characteristics of mesenteric adenitis in Korean adults", J Korean Med Sci, 12(2), pp.105~110 (1997)
  8. Xu KS, "Clinical efficacy of modified qiwei baizhu powder in treatment of mesenteric lymphadenitis in children : an analysis of 36 case", J Anhui Univ Chin Med, 35, pp.33~35 (2016)
  9. Chen LF, "Clinical observation of wangshi baochi pill in the treatment of children with mesenteric lymphadenitis", Shanghai Med Pharm J, 23, pp.40~42 (2023)
  10. Zhai CT, "Effect of xiangsha pingwei powder on infantile mesenteric lymphadenitis(syndrome of milk and food retention and stagnation)", Health Med Res Prac, 20(5), pp.69~72 (2023)
  11. Fang JQ, "Efficacy observation of baohe pills combined with amoxicillin and clavulanate potassium in the treatment of children with mesenteric lymphadenitis", Chin J Mod Drug Appl, 17(22), pp.115~118 (2023)
  12. Lin YC, "Curative effect of modified guizhi decoction combined with antibiotic therapy on preschool children with mesenteric lymphadenitis", Liaoning J Tradit Chin Med, 50(5), pp.101~104 (2023)
  13. Chen K, "Clinical observation on 42 cases of mesenteric lymph nodes in children with syndrome of cold and heat complex treated by modified banxia xiexin tang as adjuvant therapy", J Pediatrics TCM, 18(1), pp.71~74 (2022)
  14. Wang C, "Clinical efficacy of xiangsha pingwei powder in the treatment of infantile mesenteric lymphadenitis", J Changchun Univ Chin Med, 38(4), pp.424~427 (2022)
  15. Yi XL, "Modified bupleurum relieving liver-qi powder combined with western medicine in treatment of 60cases of children with mesenteric lymphadenitis", Smart healthcare, 15, pp.88~90 (2022)
  16. Li YY, "Efficacy observation of weichangan pill combined with cefixime in the treatment of children with mesenteric lymphadenitis", Chin J Mod Drug Appl, 26(18), pp.136~138 (2022)
  17. Huang CY, "Clinical study of hehe xiaoxuan powder combined with 654-2 tablets in the treatment of mesenteric lymphadenitis in children", J China & Foreign Med Treatment, 32, pp.31~34 (2021)
  18. Chen YH, "Clinical effect of sanjie zhitong prescription in the treatment of mesenteric lymphadenitis in children", J Clin Res Pract, 6(22), pp.122~124 (2021)
  19. Zhao YL, "Clinical effect of modified chaihu guizhi decoction in the treatment of mesenteric lymphadenitis in children with spleen-stomach damp-heat syndrome", J Clin Res Pract, 6(31), pp.141~143 (2021)
  20. Zhao Y, "Analysis of therapeutic effect of wumei decoction on children mesenteric lymphadenitis", Contemp Med, 27(20), pp.86~87 (2021)
  21. Zhang L, "Curative effect observation of modified chaihu guizhi decoction on mesenteric lymphadenitis in children", J Liaoning Univ TCM, 23(12), pp.208~211 (2021)
  22. Wang XM, "A clinical efficacy study on modified chaihu shugan powder in the treatment of infantile mesenteric lymphadenitis(pattern of qi stagnation and blood stasis)", Jilin J Chin Med, 41(12), pp.1620~1623 (2021)
  23. Xu SS, "Clinical research of modified yueju pill combined with amoxicillin and clavulanate potassium for mesenteric lymphadenitis in children", Hebei J TCM, 43(8), pp.1323~1326 (2021)
  24. Chen Y, "Effects of chaihu guizhi decoction on patients with mesenteric lymphadenitis(dampness-heat syndromes in spleen and stomach)", World Chin Med, 15(9), pp.1335~1338 (2020)
  25. Wang ZM, "Clinical observation of modified shenling baizhu powder on mesenteric lymphadenitis in children", Shanxi J TCM, 36(11), pp.14~16 (2020)
  26. Chang WL, "Effect of zhongsan combined with cefaclor chewable tablets on mesenteric lymphadenitis and digestive function in children", Chin J Integr Trad West Med Dig, 28(6), pp.449~453 (2020)
  27. Liang R, "Clinical study on baoji oral liquid for mesenteric lymphadenitis in children", J New Chin Med, 52(12), pp.11~12 (2020)
  28. Yoo JS, "Clinical characteristics of acute surgical abdomen and mesenteric lymphadenitis in children with acute abdominal pain", Kyung Hee Med J, 22(1), pp.43~51 (2006)
  29. Ianiro G, "Antibiotics as deep modulators of gut microbiota : between good and evil", Gut, 65(11), pp.1906~1915 (2016)
  30. Wang B, "New compilation of huangjenaegyeongsomun", pp.244~ (1999), Daeseong Munhwasa
  31. Li C, "Uihagimmun", pp.150~ (1990), Daeseong Munhwasa
  32. Heo J, "Dongui bogam", pp.696~1711 (1999), Bobin Munhwasa
  33. Kim DG, "Dongui Pediatrics", pp.294~298 (2002), Jeongdam
  34. Jung JH, "A case report of mesenteric lymphadenitis with diarrhea", J Pediatr Korean Med, 22(3), pp.75~82 (2008)
  35. Wang Q, "Efficacy of thunder-fire moxibustion combined with xiaojianzhong decoction on pediatric abdominal pain of cold in the middle abdomen type", Mod Chin Clin Med, 28(3), pp.1~5 (2021)
  36. Sheng HY, "Clinical curative effect of abdominal pain medicine powder acupoint in the treatment of mesenteric lymphadenitis in children", China Health Standard Management, 8(6), pp.75~76 (2017)
  37. Wang C, "Clinical study on modified xiangsha pingwei powder combined with infantile massage in the treatment of children with mesenteric lymphadenitis", Hebei J TCM, 42(5), pp.677~681 (2020)
  38. Hu YM, "Zhu futang practical pediatrics", pp.1362~ (2002), People's Med Pub House Co
  39. Wang SC, "Chinese pediatrics", pp.166~167 (2009), People's Med Pub House Co
  40. Kim JE, "Mesenteric lymph nodes identified on us : clinical significance in symptomatic and asymptomatic children", USG, 19(4), pp.305~309 (2000)
  41. Zhang ZJ, "Geumgweyoryakbyeonseok", pp.265~266 (2012), Hanui Pub Co
  42. Lee SH, "4 cases of chronic abdominal pain children treated by sihogyeji-tanggagam with acupuncture and moxibustion treatment", J Physiol & Pathol Korean Med, 35(6), pp.261~266 (2021)

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