소아 구내염의 한약치료에 대한 임상연구 동향: 중의학 무작위대조군 임상시험을 중심으로
A Review of Recent Clinical Studies of Herbal Medicine Treatment for Children’s Stomatitis : Focusing on Randomized Controlled Trials in Traditional Chinese Medicine
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Objectives This study aims to find out the recent trend of the herbal medicine treatment in children’s stomatitis in China, and propose better methods to treat children’s stomatitis in Korea. Methods The randomized controlled trials (RCT) relevant to ‘Herbal medicine treatment on children’s stomatitis’ were searched using China Academic Journal (CAJ). The search method we used included search formula, (SU = '口內炎' + '口腔炎' + 'stomatitis') and (SU = '儿童' + '小儿' + 'children' + 'child') from 2000 to September 2021. Results A total of 9 RCTs were selected and analyzed. All reports showed that oral administration of herbal medicine were effective and improved clinical symptoms. The most-used herbal medicine category was Heat-clearing medicine (淸熱藥). Conclusions The literatures from China have shown that herbal medicine improves children’s stomatitis. These outcomes may be helpful for the treatment of children’s stomatitis in Korea. However, further studies are needed to develop treatment guidelines for children’s stomatitis.
Abstract
Objectives This study aims to find out the recent trend of the herbal medicine treatment in children’s stomatitis in China, and propose better methods to treat children’s stomatitis in Korea. Methods The randomized controlled trials (RCT) relevant to ‘Herbal medicine treatment on children’s stomatitis’ were searched using China Academic Journal (CAJ). The search method we used included search formula, (SU = '口內炎' + '口腔炎' + 'stomatitis') and (SU = '儿童' + '小儿' + 'children' + 'child') from 2000 to September 2021. Results A total of 9 RCTs were selected and analyzed. All reports showed that oral administration of herbal medicine were effective and improved clinical symptoms. The most-used herbal medicine category was Heat-clearing medicine (淸熱藥). Conclusions The literatures from China have shown that herbal medicine improves children’s stomatitis. These outcomes may be helpful for the treatment of children’s stomatitis in Korea. However, further studies are needed to develop treatment guidelines for children’s stomatitis.
참고문헌 (36)
- College of Oriental Medicine Compilation Committee of Ophthalmology & Otolaryngology & Dermatology, "Korean medicine otorhinolaryngology", pp.339~ (2016), Sunwoo
- Jeong JY, "Common skin diseases in Korea", pp.348~352 (2009), Mdworld
- National health insurance service, health insurance review & assement service, "2019 National health insurancce statistical yearbook", pp.601~ (2019), Hanaro vocational training center
- Nolan A, "Recurrent aphthous ulceration : vitamin B1, B2 and B6 status and response to replacement therapy", J Oral Pathol Med, 20(8), pp.389~391 (1991)
- Crighton AJ, "Oral medicine in children", Br Dent J, 223(9), pp.706~712 (2017)
- Gherunpong S, "The prevalence and severity of oral impacts on daily performances in Thai primary school children", Health Qual Life Outcomes, 2(1), pp.1~8 (2004)
- Department of Pediatrics Nationwide Korean Medicine College, "Pediatrics of Korean medicine", pp.109~ (2020), Uisungdang
- Eilers J, "Assessment and measurement of oral mucositis", Semin Oncol Nurs, 20(1), pp.22~29 (2004)
- Sunagawa M, "Kampo(traditional Japanese herbal)formulae for treatment of stomatitis and oral mucositis", Medicines, 5(4), pp.130~ (2018)
- Gu YH, "Vitamin B2 functionalized iron oxide nanozymes for mouth ulcer healing", Sci China Life Sci, 63(1), pp.68~79 (2020)
- Nguyen S, "Advanced drug delivery systems for local treatment of the oral cavity", Ther Deliv, 6(5), pp.595~608 (2015)
- 주경옥, "한약처방과 외용약을 병용한 口瘡 환자 치험 1례", 한방안이비인후피부과학회지, 21(2), pp.184~190 (2008), 대한한방안이비인후피부과학회
- The Korean Society of Herbal Medicine, "Bonchohak", pp.199~201 (2014), Yeongminsa
- Cai QH, "A randomized controlled, multi-center clinical study of kouyanqing granules in treatment of infantile herpetic stomatitis(syndrome of yin-deficiency and windheat)", Drug Evaluation Res, 43(9), pp.1792~1796 (2020)
- Wang HY, "Therapeutic effect of jiawei sanwu huangqin decoction on children with recurrent aphthous ulcer of heart and spleen heat accumulation syndrome", Master, pp.2019
- Fang J, "The clinical observation on the effect of qingxinpi keli in treating 63 cases of heat accumulated in heart and spleen type aphtha in children", J Pediatr of TCM, 14(3), pp.43~46 (2018)
- Zhang Y, "Observation on clinical curative effects of modified xiexin daochi decoction in herpetic stomatitis", J of Chengdu Univ of TCM, 39(2), pp.98~100 (2016)
- Zhong SX, "Clinical observation on the effect of additional xiehuang san in treating herpetic stomatitis in children (Damp-heat syndrome of spleen and stomach", Master, pp.2015
- Qian HH, "Clear mist particles in the treatment of infantile herpetic stomatitis clinical of cases of excessive heat", Master, pp.2014
- Jiang HY, "Clinical study of combination of traditional Chinese medicine with western medicine in treatment of 40 child patients with herpetic stomatitis", Forum on TCM, 29(6), pp.34~ (2014)
- Shao H, "The clinical observation on clinical curative effects of xiepishengqing decoction in 30 children with herpetic somatitis", Nei Mongol J of TCM, 33(35), pp.20~ (2014)
- Lu CF, "Clinical study of combination of traditional Chinese medicine with western medicine in treatment of 40 child patients with herpetic stomatitis", J Pediatr Pharm, 12(5), pp.55~57 (2006)
- Montgomery-Cranny JA, "Management of recurrent aphthous stomatitis in children", Dent Update, 42(6), pp.564~572 (2015)
- O’ Donnell SC, ""Surviving the sting" : the use of solicited diaries in children and young people with oral mucosal disease", Int J Paediatr Dent, 23(5), pp.352~358 (2013)
- 정한솔, "口瘡의 문헌연구", 동의생리병리학회지, 16(1), pp.5~44 (2002), 한의병리학회
- Jung JY, "A study of literature review on the etiology & pathologic mechanism and on the acupunture & moxibustion treatment for gu-chang", J of Haehwa Medicine, 13(1), pp.243~254 (2004)
- 하나연, "한약 치료를 시행한 재발성 아프타성 구내염 환자의 임상소견에 관한 추적 관찰 연구", 대한한방내과학회지, 38(5), pp.812~819 (2017), 대한한방내과학회
- 김태준, "한방 치료로 호전된 재발성 아프타성 구내염 치험 1례 - 淸熱導痰湯加減과 當歸鬚散合乳香定痛散加減 사용효과를 중점으로", 한방안이비인후피부과학회지, 33(2), pp.140~155 (2020), 대한한방안이비인후피부과학회[DOI]
- 김지환, "팔물군자탕 가미방으로 호전된 재발성 아프타성 구내염 및 한포진 환자 치험 1례", 사상체질의학회지, 32(2), pp.80~95 (2020), 사상체질의학회[DOI]
- 김주연, "재발성 아프타성 구내염 환자에 대한 가미육미지황탕의 효능", 대한한방내과학회지, 33(2), pp.231~242 (2012), 대한한방내과학회
- Oh SH, "Herpes simplex virus infection in children", Korean J of Pediatric Infectious Diseases, 4(1), pp.37~42 (1997)
- Shin MH, "Literatual study on gu-chang", J Korean Med, 13(1), pp.163~176 (1992)
- Cho G, "Seongjechongrok vol.116", pp.213~ (1977), Hanseongsa
- Quinn B, "Ensuring accurate oral mucositis assessment in the European group for blood and marrow transplantation prospective oral mucositis audit", Eur J Oncol Nur, 11(1), pp.S10~ (2007)
- Gilchrist F, "Assessment of the quality of measures of child oral health-related quality of life", BMC Oral Health, 14(1), pp.1~17 (2014)
- 오명호, "소아 임상연구에서의 의료 윤리적 고려사항", Clinical and Experimental Pediatrics, 52(1), pp.1~5 (2009), 대한소아청소년과학회
