유산소운동이 혈장 유리칼슘 농도 조절에 미치는 영향
The Effect of Aerobic Exercise on the Regulation of Blood Ionized Calcium Concentration
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본 연구는 30분간 60%HRmax 유산소 운동이 혈장 유리칼슘 농도 조절에 부갑상선 호르몬 혹은 pH인자 중 어떤 인자가 영향을 주는가를 알아보는데 목적이 있다. 연구 대상은 건강한 남자대학생 14명을 운동군, 대조군 각각 7명씩 무작위로 나누었고 운동군은 60%HRmax 유산소 달리기 운동을 30분간 주3회 8주간을 실시하였다. 두 군 모두 60%HRmax 일회성 유산소 달리기 운동 30분을 실시하여 운동전, 운동직후, 회복기 5분, 10분, 30분에 전완에서 10ml 혈액을 채혈하였으며 이온화 칼슘과 pH는 전해질 분석기로, 총칼슘은 자동생화학분석기로, 알부민은 생화학분석기로 분석하였다. 부갑상선호르몬은 감마 카운터로, 혈장 젖산과 암모니아의 측정은 생화학분석기로, 케톤체 측정은 Mass Selective detector로 분석하여 비교 검토한 결과는 다음과 같다. 혈장 알부민농도는 운동전에 비해 운동 직후 운동군, 대조군 모두 유의하게 증가(p<.001)하였고, 혈장 총칼슘은 두 군 모두 유의하게 증가(p<.001)하였으나, 혈장 이온화칼슘농도는 두 군 모두 유의하게 감소(p<.001)하였다. 대사산물인 혈장 젖산(p<.001)과 암모니아(p<.001)가 유의하게 증가되어 pH농도가 유의하게 저하(p<.001)되었다. 한편 부갑상선 호르몬은 두 군 모두 유의하게 증가(p<.001)하였다. 회복기에서 유리칼슘과 케톤체 농도는 5분에, 젖산은 30분에 회복되었으나 다른 변인들은 30분이 되어도 회복되지 못하였다. 이상의 결과에서 일회성 유산소 운동은 트레이닝을 한 사람이나 안 한 사람이나 혈장 유리 이온화 칼슘 농도의 조절은 부갑상선 호르몬과 pH인자 모두가 영향을 주는 것으로 시사되었다.
Abstract
The aim of the present study was to examine how the concentration of blood ionized calcium(Ca++) would change due to pH or parathyroid hormone as a single bout of aerobic exercise. The divided into two groups ; the one is exercise group(n=7), the other is control group(n=7). The exercise group was taken for 30min 60%HRmax aerobic exercise training three times in a week for eight weeks. All subjects were taken 30minute of 60%HRmax on treadmill running, Blood sampling was done pre, post and recovery (5,10 or 30min) from subjects. The plasma albumin concentrations in the both groups were significantly(p<0.001) increased immediately post-exercise compared to pre-exercise. The plasma total Ca concentrations were significantly(p<0.001) increased, while the ionized Ca++ concentrations in the all subjects were significantly(p<0.001) decreased immediately post-exercise compared to the pre-exercise. The lactate(p<0.001) and NH3 (p<0.001) concentrations were significantly in creased, because the pH was significantly(p<0.001) dropped. The plasma PTH concentration was significantly(p<0.001) increased in the exercise group than in the control group. It suggest that the pH and PTH concentration altogether gave to effect the regulation of ionized calcium concentration in a single bout of the aerobic exercise. Further study is needed to clarify the physiological implications of a intensity due to exercise and also it mechanism.
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