화장품 소재로서 밀싹 추출물의 고온 보존이 항산화력 및 경피 수분 증발량에 미치는 영향
Impact of High Temperature Preservation of Wheat Sprout Extracts as Cosmetic Ingredient on Anti-oxidation Activity and Amount of Percutaneous Moisture Evaporation
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
목적: 본 연구는 밀싹 추출물을 활용하여 고온 보존 시 항산화력에 미치는 영향을 살펴보고, 밀싹 추출물을 함유한 크림이화 장품소재로서 활용 가능성에 대하여 확인하고자 하였다. 방법: 고온 보존된 밀싹 추출물의 항산화력 변화와 피부 경피 수분 증발량 변화를 측정하였다. 결과: 밀싹 추출물은 고온 보존 시간에 따라 항산화력이 고온 보존 전보다 감소하는 것을 확인할 수 있었다. 밀싹 추출물을 함유한크림을 인체 피부에 적용하여 인체폐쇄첩포시험을 실시한 결과 시험 기간 중 피부 이상반응을 나타나지 않았으며, 밀싹을 함유한크림은 일반 크림보다 손상된 피부 장벽 기능을 효과적으로 복원시켜 주고, 경피 수분 증발량을 효과적으로 줄여주어피 부 장벽 기능에도움을 주는 것으로 확인하였다. 결론: 본 연구결과를 바탕으로 밀싹 추출물은 고온 보존에 불안정하여 화장품 소재로 활용 시 50℃ 이하에서 유화시키는 것이 항산화력 유지에 도움이 될 것으로 사료되며, 경피 수분 증발량을 효과적으로 줄여주는 것으로 보아 화장품 소재로서의 활용 가능성이있을 것으로 사료된다.
Abstract
Purpose: One of the objects in this study is to investigate the effect of high temperature preserved wheat sprout extracts on anti-oxidant activity. The other is to confirm the feasibility of the cream containing wheat sprout extracts as cosmetic materials. Methods: We performed the anti-oxidant assay and skin clinical testing to check the anti-oxidant activity and the transepidermal water loss index, respectively. Results: The anti-oxidant activity of wheat sprout extracts was decreased after the high temperature preservation than before. In the skin clinical testing of the cream with wheat sprout extracts, we found out that the cream restored the damaged skin barrier effectively by reducing the evaporation of skin. Conclusion: Based on our findings, we suggest that wheat sprout extracts should be melted below 50 degrees Celsius to preserve the anti-oxidant activity. As the extracts reduced skin moisture loss effectively, wheat sprout extracts are considered having the potential as cosmetic materials.
참고문헌 (26)
- Aydos OS, "Antiproliferative, apoptotic and antioxidant activities of wheatgrass (Triticum aestivum L.) extract on CML (K562) cell line", Turkish Journal of Medical Sciences, 41, pp.657~663 (2011)
- Bar-Sela G, "Wheat grass juice may improve hematological toxicity related to chemotherapy in breast cancer patients: a pilot study", Nutrition and Cancer, 58, pp.43~48 (2007)
- Blois MS, "Antioxidant determinations by the use of a stable free radical", Nature, 181, pp.1199~1200 (1958)
- Bonfili L, "Wheat sprout extract-induced apoptosis in human cancer cells by proteasomes modulation", Biochimie, 91, pp.1131~1144 (2009)
- Brandner JM, "Organization and formation of the tight junction system in human epidermis and cultured keratinocytes", European Journal of Cell Biology, 81, pp.253~263 (2002)
- Calzuola I, "Short acidic peptides isolated from wheat sprout chromatin and involved in the control of cell proliferation: characterization by infrared spectroscopy and mass spectrometry", Peptides, 26, pp.2074~2085 (2005)
- Calzuola I, "Synthesis of antioxidants in wheat sprouts", Journal of Agricultural and Food Chemistry, 52, pp.5201~5206 (2004)
- Chaqour B, "Chronic UVB- and all-trans retinoic-acidinduced qualitative and quantitative changes in hairless mouse skin", Journal of Photochemistry and Photobiology B: biology, 28, pp.125~135 (1995)
- Choudhary DR, "Effect of wheat grass therapy on transfusion requirement in beta-thalassemia major", The Indian Journal of Pediatrics, 76, pp.375~376 (2009)
- Falcioni G, "Antioxidant activity of wheat sprouts extract in vitro : inhibition of DNA oxidative damage", Journal of Food Science, 67, pp.2918~2922 (2002)
- Folin O, "On phosphotungstic-phosphomolybdic compounds as color reagents", The Journal of Biological Chemistry, 12, pp.239~243 (1912)
- Gutfinger T, "Polyphenols in olive oils", Journal of the American Oil Chemists Society, 58, pp.966~968 (1981)
- 하진옥, "순무 싹의 화학성분과 생리기능성", 한국식품영양과학회지, 38(10), pp.1302~1309 (2009), 한국식품영양과학회
- Janthachotikun S, "The anti-inflammatory effects of wheat germ oil on lipopolysaccharide-activated human monocytic (THP-1) cells", The Federation of American Societies for Experimental Biology Journal, 29, pp.608.26~ (2015)
- Jungersted JM, "Skin barrier response to occlusion of healthy and irritated skin: differences in trans-epidermal water loss, erythema and stratum corneum lipids", Contact Dermatitis, 63, pp.313~319 (2010)
- 김덕숙, "새싹채소의 생리활성 특성 및 그 가공품의 제조", 한국식품조리과학회지, 26(3), pp.238~245 (2010), 한국식품조리과학회
- 김정기, "콜라겐 펩타이드의 피부 장벽 보호 효과", 한국식품과학회지, 43(4), pp.458~463 (2011), 한국식품과학회
- 김상현, "피부장벽손상이 TEWL에 미치는 영향과 호호바 오일의 피부장벽복구 역할에 대한 연구", 아시안뷰티화장품학술지, 3(1), pp.189~200 (2005), 한국피부과학연구원
- Meyerowitz S., "Wheatgrass, nature’s finest medicine: the complete guide to using grass, foods & juices to help your health", pp.53~ (1999), Sproutman Publications
- Moreno MI, "Comparison of the free radical-scavenging activity of propolis from several regions of Argentina", Journal of Ethnopharmacology, 71, pp.109~114 (2000)
- Okarter N, "Phenolic compounds from the insoluble-bound fraction of whole grains do not have any cellular antioxidant activity", Life Sciences and Medicine Research, LSMR-37 (2012)
- Reddy BS, "Preventive potential of wheat bran fractions against experimental colon carcinogenesis: implications for human colon cancer prevention", Cancer Research, 60, pp.4792~4797 (2000)
- Rissmann R, "Skin barrier disruption by acetone:observations in a hairless mouse skin model", Archives of Dermatological Research, 301, pp.609~613 (2009)
- Singh K, "Effect of wheat grass tablets on the frequency of blood transfusions in thalassemia major", The Indian Journal of Pediatrics, 77, pp.90~91 (2010)
- Tudek B, "The effect of wheat sprout extract on benzo(a)pyrene and 7,2-dimethylbenz(a)anthracene activity", Neoplasma, 35, pp.515~523 (1988)
- 유선희, "밀싹 에탄올 추출물의 항산화 및 항염증 활성", 대한미용학회지, 11(3), pp.231~238 (2015), 대한미용학회[DOI]