쥐의 교정적 치아이동에 있어서 발치와의 의도적 드릴링에 의한 조직학적 효과
Histologic effects of intentional drilling on extraction socket in orthodontic movements in rats
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The application of surgical method in orthodontic tooth movement is known to accelerate tooth movement by inducing Regional acceleratory phenomenon(RAP) that activates the remodeling of periodontal tissue on damaged site. The aim of this study is to histologically evaluate the effect of the elimination of periodontal ligament(PDL) by drilling the extraction socket on osteoclastic activity during orthodontic tooth movement in rats. Twenty-four Spraque-Dawley rats with an average weight of 400 g were used in this study. Both of the first molar were extracted, then the socket was drilled in experimental group. A traction force(100g) was applied to the second molar with coiled spring. After the sacrifice on 3rd, 7th, 10th, and 14th day, H&E staining and Tartrate-resistant acid phosphatase (TRAP) staining were performed. The bone resorption at compression side in experimental group was observed earlier and continued longer than that of control group. Osteoclast count and the results of immunohistochemical analysis suggested elevated bone remodeling activity in both groups, especially in experimental group. Thus, intentional drilling on extraction socket to eliminate PDL is considered effective in rapid orthodontic treatment.
Abstract
The application of surgical method in orthodontic tooth movement is known to accelerate tooth movement by inducing Regional acceleratory phenomenon(RAP) that activates the remodeling of periodontal tissue on damaged site. The aim of this study is to histologically evaluate the effect of the elimination of periodontal ligament(PDL) by drilling the extraction socket on osteoclastic activity during orthodontic tooth movement in rats. Twenty-four Spraque-Dawley rats with an average weight of 400 g were used in this study. Both of the first molar were extracted, then the socket was drilled in experimental group. A traction force(100g) was applied to the second molar with coiled spring. After the sacrifice on 3rd, 7th, 10th, and 14th day, H&E staining and Tartrate-resistant acid phosphatase (TRAP) staining were performed. The bone resorption at compression side in experimental group was observed earlier and continued longer than that of control group. Osteoclast count and the results of immunohistochemical analysis suggested elevated bone remodeling activity in both groups, especially in experimental group. Thus, intentional drilling on extraction socket to eliminate PDL is considered effective in rapid orthodontic treatment.
참고문헌 (22)
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