Anti-wrinkle Effects of Impatiens textori Methanol Extract
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초록
We evaluated the anti-wrinkle effects of Impatiens textori methanol extract (ITME). ITME treatment at 10 mg/mL decreased collagenase and elastase activity by 50.4% and 54.9%, respectively. In tests of human dermal fibroblast cytotoxicity, the maximum permissible level of ITME treatment was greater than 200 μg/mL. When compared to a control: i) treatment with 200 μg/mL of ITME significantly increased type I procollagen synthesis by 36.7% (p<0.05), and ii) treatment with 100 μg/mL ITME significantly decreased MMP-1 mRNA and protein expression by 23.1% and 35.3%, respectively (p< 0.01). Treatment with ITME resulted in a promotion of collagen synthesis and inhibition of collagen degradation in human dermal fibroblasts. Collectively, these results suggest that ITME could be used as functional cosmetic material to prevent or alleviate skin wrinkles induced by ultraviolet rays.
Abstract
We evaluated the anti-wrinkle effects of Impatiens textori methanol extract (ITME). ITME treatment at 10 mg/mL decreased collagenase and elastase activity by 50.4% and 54.9%, respectively. In tests of human dermal fibroblast cytotoxicity, the maximum permissible level of ITME treatment was greater than 200 μg/mL. When compared to a control: i) treatment with 200 μg/mL of ITME significantly increased type I procollagen synthesis by 36.7% (p<0.05), and ii) treatment with 100 μg/mL ITME significantly decreased MMP-1 mRNA and protein expression by 23.1% and 35.3%, respectively (p< 0.01). Treatment with ITME resulted in a promotion of collagen synthesis and inhibition of collagen degradation in human dermal fibroblasts. Collectively, these results suggest that ITME could be used as functional cosmetic material to prevent or alleviate skin wrinkles induced by ultraviolet rays.
참고문헌 (27)
- Almine JF, "Elastin-based materials", Chem Soc Rev, 39, pp.3371~3379 (2010)
- Aström A, "Molecular cloning of two human cellular retinoic acid-binding proteins (CRABP). Retinoic acid-induced expression of CRABP-II but not CRABP-I in adult human skin in vivo and in skin fibroblasts in vitro", J Biol Chem, 266, pp.17662~17666 (1991)
- Berneburg M, "How best to halt and", or revert UV-induced skin ageing: strategies, facts and fiction, 2008, pp.17, 228~229
- Brennan M, "Matrix metalloproteinase-1 is the major collagenolytic enzyme responsible for collagen damage in UV-irradiated human skin", Photochem Photobiol, 78, pp.43~48 (2003)
- Bruckner-Tuderman L, "Tissue form of type VII collagen from human skin and dermal fibroblasts in culture", Eur J Biochem, 165, pp.607~611 (1987)
- Chen CL, "Protective effects of chlorella-derived peptide on UVB-induced production of MMP-1and degradation of procollagen genes in human skin fibroblasts", Regul Toxicol Pharmacol, 60, pp.112~119 (2011)
- Di Lullo GA, "Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen", J Biol Chem, 277, pp.4223~4231 (2002)
- El-Domyati M, "Intrinsic aging vs. photoaging: a comparative histopathological, immunohistochemical, and ultrastructural study of skin", Exp Dermatol, 11, pp.398~405 (2002)
- Fisher GJ, "Molecular basis of sun-induced premature skin ageing and retinoid antagonism", Nature, 379, pp.335~339 (1996)
- Fisher GJ, "Looking older: fibroblast collapse and therapeutic implications", Arch Dermatol, 144, pp.666~672 (2008)
- Gordon MK, "Collagens", Cell Tissue Res, 339, pp.247~257 (2010)
- 황지연, "인체피부섬유아세포에서 자주달개비 메탄올 추출물의 항노화 효능", 대한미용학회지, 11(1), pp.25~32 (2015), 대한미용학회[DOI]
- 황지연, "인체피부섬유아세포에서 초석잠 에탄올 추출물의 주름형성 억제 효능", 대한미용학회지, 11(4), pp.293~301 (2015), 대한미용학회[DOI]
- Kang S, "Application of retinal to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation", J Invest Dermatol, 105, pp.549~556 (1995)
- 김수은, "Anti-wrinkle Efficacy of Oenothera laciniata Methanol Extract in Human Dermal Fibroblasts", 대한미용학회지, 12(3), pp.197~203 (2016), 대한미용학회
- Kligman AM, "Topical retinoid improves cellulite", J Dermatolog Treat, 10, pp.119~125 (1999)
- Kondo S, "The roles of cytokines in photoaging", J Dermatol Sci, 23, pp.S30~S36 (2000)
- Losso JN, "Inhibition of matrix metalloproteinase-1 activity by the soybean Bowman-Birk inhibitor", Biotechnol Lett, 26, pp.901~905 (2004)
- Massova I, "Matrix metalloproteinases:structures, evolution, and diversification", FASEB J, 12, pp.1075~1095 (1998)
- Murray AA, "Role of ascorbic acid in promoting follicle integrity and survival in intact mouse ovarian follicles in vitro", Reproduction, 121, pp.89~96 (2001)
- 박별례, "Utility of Impatiens textori Methanol Extract as an Antioxidant and Natural Preservative for Cosmetics", 대한미용학회지, 12(4), pp.299~303 (2016), 대한미용학회[DOI]
- Pfeffer F, "Modulation of 72-kilodalton type IV collagenase (matrix metalloproteinase-2) by ascorbic acid in cultured human amnion-derived cells", Biol Reprod, 59, pp.326~329 (1998)
- Son ED, "Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice", Biol Pharm Bull, 30, pp.1395~1399 (2007)
- Talwar HS, "Reduced type I and type III procollagens in photodamaged adult human skin", J Invest Dermatol, 105, pp.285~290 (1995)
- Ueda Y, "Effects on blood pressure decrease in response to PAF of Impatiens textori MIQ", Biol Pharm Bull, 26, pp.1505~1507 (2003)
- Wiedow O, "Elafin: an elastase-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence", J Biol Chem, 265, pp.14791~14795 (1990)
- Yaar M, "Aging versus photoaging: postulated mechanisms and effectors", J Investig Dermatol Symp Proc, 3, pp.47~51 (1998)