홍삼농축액과 제주 용암해수 혼합시료의 항염 및 항산화 효능
Anti-inflammatory and Anti-oxidant of the Mixture of Jeju Lava Seawater and Red Ginseng Extracts
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With increasing interest in wellness, health, and functional cosmetics, Jeju lava seawater and red ginseng are widely used in many industrial products as foods and cosmetics. In this study, analysis of the amount of inflammatory cytokine production was performed using various cells of HaCaT, Hs68, and THP-1 in order to confirm the broad anti-inflammatory effect of a mixture of Jeju lava seawater and red ginseng extract. The results of experiments showed that expression of inflammatory cytokines (IL-6, IL-8, TNF-α) increased by LPS in the epidermis, dermis, and immune cells was significantly inhibited by the mixture of Jeju lava seawater and red ginseng extract. In addition, an antioxidant effect of the mixture was demonstrated, with results showing a significant inhibitory effect in a dose- dependent manner. These results demonstrated the potential of the mixture of Jeju lava seawater and red ginseng extract as an effective substance that may have an antioxidant effect and provide relief from inflammation.
Abstract
With increasing interest in wellness, health, and functional cosmetics, Jeju lava seawater and red ginseng are widely used in many industrial products as foods and cosmetics. In this study, analysis of the amount of inflammatory cytokine production was performed using various cells of HaCaT, Hs68, and THP-1 in order to confirm the broad anti-inflammatory effect of a mixture of Jeju lava seawater and red ginseng extract. The results of experiments showed that expression of inflammatory cytokines (IL-6, IL-8, TNF-α) increased by LPS in the epidermis, dermis, and immune cells was significantly inhibited by the mixture of Jeju lava seawater and red ginseng extract. In addition, an antioxidant effect of the mixture was demonstrated, with results showing a significant inhibitory effect in a dose- dependent manner. These results demonstrated the potential of the mixture of Jeju lava seawater and red ginseng extract as an effective substance that may have an antioxidant effect and provide relief from inflammation.
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